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The map label for this gene is lepB [H]

Identifier: 167038702

GI number: 167038702

Start: 30895

End: 31425

Strand: Direct

Name: lepB [H]

Synonym: Teth514_0027

Alternate gene names: 167038702

Gene position: 30895-31425 (Clockwise)

Preceding gene: 167038698

Following gene: 167038703

Centisome position: 1.26

GC content: 32.02

Gene sequence:

>531_bases
ATGAGCAAAAACATAAAAAAGGAAATATTAAGCTGGATATTTACTATAGCTCTTGCTTTTTTGATTGCACTGTTTATAAG
GACTTATGTTTTTGAATTGGTAGATGTACCCACAGGTTCAATGTTAAATACTATTCAAATAAATGATAAATTCATTGTAA
ACAAGTTTATATACAGGTTTGAACCTGTAAAACGAGGAGATATTGTAGTATTTCGCTTTCCTGACGACCCAAAAGTTAAT
TTTGTAAAAAGAGTTATTGGCATTGGTGGAGATGTGATTGAAATAAAAAATGGTCAGTTAATAAGAAATGGAAAAGTAGT
TAAGGAGCCCTATATAAAAGAACCTATGAAAGGCAATTTTGGACCATATGTCGTTCCACCGGGTCATTATTTTATGTTAG
GTGATAATAGAAATGAGTCTATGGACAGTAGATTTTGGCAGCACAAGTATGTATCAAAAGACCAAATTTTGGGCAAAATA
GTTTTTAGAATTTGGCCTCCTGATCGAATTGGTTCTATGTCTGGAAAATAG

Upstream 100 bases:

>100_bases
TGACATATATTAGAAAAATATGCATACAAAATAAAAAAATTAGAATTTGTTTGAAGTTTATGCTATAATATCACTGTACT
TTTAAGTGAGGAGAGAAAAT

Downstream 100 bases:

>100_bases
TTATTGAAAGTAGTGTTATAAAGTAGTATAATATTAAAAAACATAATATTGTCGGCAATGAAGGGACGAGTAGTAAGTAT
AAACTTTTAAGAGAGCTGGT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSKNIKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRFEPVKRGDIVVFRFPDDPKVN
FVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKI
VFRIWPPDRIGSMSGK

Sequences:

>Translated_176_residues
MSKNIKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRFEPVKRGDIVVFRFPDDPKVN
FVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKI
VFRIWPPDRIGSMSGK
>Mature_175_residues
SKNIKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRFEPVKRGDIVVFRFPDDPKVNF
VKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKIV
FRIWPPDRIGSMSGK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=97, Percent_Identity=38.1443298969072, Blast_Score=71, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323800, Length=156, Percent_Identity=32.6923076923077, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20388; Mature: 20257

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNIKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHC
EPVKRGDIVVFRFPDDPKVNFVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNF
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEEEECCCEECCCCCCCCCCCCC
GPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKIVFRIWPPDRIGSMSGK
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHEEECCCHHCCCCCCC
>Mature Secondary Structure 
SKNIKKEILSWIFTIALAFLIALFIRTYVFELVDVPTGSMLNTIQINDKFIVNKFIYRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHC
EPVKRGDIVVFRFPDDPKVNFVKRVIGIGGDVIEIKNGQLIRNGKVVKEPYIKEPMKGNF
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEEEECCCEECCCCCCCCCCCCC
GPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKIVFRIWPPDRIGSMSGK
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHEEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]