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The map label for this gene is flhA [H]

Identifier: 163845450

GI number: 163845450

Start: 1313800

End: 1315899

Strand: Reverse

Name: flhA [H]

Synonym: BSUIS_B1359

Alternate gene names: 163845450

Gene position: 1315899-1313800 (Counterclockwise)

Preceding gene: 163845451

Following gene: 163845449

Centisome position: 93.94

GC content: 57.86

Gene sequence:

>2100_bases
ATGAAACAAACACTTGGAGCGGTTCCAGCGGCCCGTTTAACTGGAACCGGCCCAATGTCCGTCGCGAAACAGGAGGCGGA
TGTGCAGCAGGCTGCGGCAAAACCTTTCATAAAAGGCAAATTTCTGACCGGCAGCGATATCGGGCTCGCCTTTTCCATCG
CCTTTTCCGTGCTGATCCTGATGGTTGCGCTATGGATCCAGCGCCCGCTCGATTTTTCGGCCTTTCCGACCGTTCTGCTG
ATTGCAACCATGATGCGATTGTCGCTCAATATTGCGACGACGCGCGTGATTCTCACCCACGGCAATGAGGGCTATCTGGC
GGCGGGTCATGTGATCCACGGCTTTTCGCAGTTCGTGATGGGCGGCGATTTCGTTATCGGCCTGGTCGTCTTCGCCATTC
TCATCATCGTCAATTTTCTGGTCATCACCAAGGGTGCGACCCGTATCGCGGAAGTGGGCGCGCGCTTCACGCTCGATGCT
ATTCCCGGCAAGCAGATGGCCATCGATGCCGATCTTTCATCGGGCCTGATCGATGAAAAGGAGGCGCAGCGCCGCCGCCG
TGAACTGGAGGAGGAAAGCTCTTTCTTTGGTTCCATGGATGGCGCGTCGAAATTCGTACGCGGCGATGCGATTGCCGGTC
TCATAATCACGGCCGTCAATATTTTTGGCGGCATCGTCATTGGTGCGACCCGCCATGGGATGGATATTTCGCAGGCCGCC
GATGTTTTCACCAAACTGTCGGTGGGCGATGGTCTGGTAACACAGATTCCGGCTCTGATCGTTTCGCTCGCTGCCGGGCT
TCTCGTGTCGAAAGGCGGCACGCGCGGCTCTGCCGATCAGGCGATTTTCGGCCAGCTTGGCGCTTATCCGAAGGCGCTTT
TGATTGCGGCGCTCCTGCTTTTCATTCTGGGCGTCATGCCGGGCCTTCCGGCCTTTCCGTTCTTCCTGCTCGGCGGCGCA
ATGGCGTTCGTCGGCATTGCCGTGCCGCGCCGCCAGGCGCGCCAGCGCGAGGCCGATGCCGCCGAAGCGGGCAAGAAGCA
GCGCGAGGCGGAAGAGCAGGAACCCAATTCGGTCAAGGCTTCGCTGGAAACCAACCAGATCGAGCTTTGCCTGGGCAAGC
AGCTTTCTGCCCGGCTGATCGCCTCGCAAGAGGAACTGGCGCACCGCGTCAACAAGATGCGCCGCAAATTTGCGCAGGAA
TACGGTTTCGTCATCCCCGAAATCAAGGTCACGGATGATATCGCGCTACCGCCGAAAAGCTATCGCATTAAAATTCACGG
CACAGCGGTTGCAAGCCATGAATTGCGTGTGGGCGAAATTCTGGTCGTGCTGGGCGAACGTCCGGTTCCATCCGTGCCGG
GTGAGGAAGTGCGTGAGCCTGCTTTCGGCATGCGTGCTTATTCGGTGCCGGAAACCTTCACTGCCGATTTGCGCCGCGAA
GGTTACATGACGGTGGATAATCTGTCGGTCCTGCTGACGCATTTGAGCGAGATCGTCCGTAACAATCTGGCGCAGCTTCT
TTCCTATAAGGATATGCGCATCCTGCTTGACCGGCTCGGGCCGGAATATCGCAAATTGCTGGAAGATATCTGCCCCGCAC
ATATTTCCTATTCCGGTTTGCAGGCGGTGCTGAAGCTTCTTTTGGCAGAGCGCATTTCCATCCGCAATCTGCATCTGATA
CTCGAAGCGATTGCCGAAATTGCGCCGCTCGTTCGCCGCCCGGAAATGATTGTCGAGCATGTGCGGATGCGCATGGCCCA
GCAGATTTGCGGTGACCTTTCCGATAATGGCGTGCTCAATGTCCTGCGCCTTGGCAACCGCTGGGATCTGGTCTTCCACC
AAAGCCTCAAACGCGACGCCAAGGGCGAAATCGTGGAATTCGATATCGATCCGCGCCTTCTGGAACAGTTCGGCACGGAG
GCCTCCGCCGCCATTCGCAAGCATTTCGATAATGGCGAGCGATTCGTACTGGTCTCCTCGCCGGAGGCGCGGCCCTATAT
TCGCATGATTATCGAACGCCTGTTCGCCACGCTGCCCGTGCTTTCGCATGTCGAAATCGCCCGTGGCGTGGAGGTGAAAT
CGCTCGGCGCGATTTCCTGA

Upstream 100 bases:

>100_bases
CGCATCGAAAAGGGTTTTTAAGAGCGTAGCCTTCGCGCAAGCTTCGCGAGGTAGAGCATTTCCAGCAAAAGTGTGAAGCG
GTTTTGCGTTGAAAAATGCG

Downstream 100 bases:

>100_bases
CCGGGAGAGACCCCGTTGCCTGTCACGCAACTGCCGCTCAACGAAATCATCCTGGCCGCCGTGCTGGCGTTTTGCCGCAT
TGGCGCATGTCTCATGCTGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAFSIAFSVLILMVALWIQRPLDFSAFPTVLL
IATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVMGGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDA
IPGKQMAIDADLSSGLIDEKEAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAA
DVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLLFILGVMPGLPAFPFFLLGGA
MAFVGIAVPRRQARQREADAAEAGKKQREAEEQEPNSVKASLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQE
YGFVIPEIKVTDDIALPPKSYRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRRE
GYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGLQAVLKLLLAERISIRNLHLI
LEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLNVLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTE
ASAAIRKHFDNGERFVLVSSPEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS

Sequences:

>Translated_699_residues
MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAFSIAFSVLILMVALWIQRPLDFSAFPTVLL
IATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVMGGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDA
IPGKQMAIDADLSSGLIDEKEAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAA
DVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLLFILGVMPGLPAFPFFLLGGA
MAFVGIAVPRRQARQREADAAEAGKKQREAEEQEPNSVKASLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQE
YGFVIPEIKVTDDIALPPKSYRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRRE
GYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGLQAVLKLLLAERISIRNLHLI
LEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLNVLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTE
ASAAIRKHFDNGERFVLVSSPEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS
>Mature_699_residues
MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAFSIAFSVLILMVALWIQRPLDFSAFPTVLL
IATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVMGGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDA
IPGKQMAIDADLSSGLIDEKEAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAA
DVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLLFILGVMPGLPAFPFFLLGGA
MAFVGIAVPRRQARQREADAAEAGKKQREAEEQEPNSVKASLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQE
YGFVIPEIKVTDDIALPPKSYRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRRE
GYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGLQAVLKLLLAERISIRNLHLI
LEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLNVLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTE
ASAAIRKHFDNGERFVLVSSPEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS

Specific function: Required for formation of the rod structure of the flagellar apparatus. May constitute the export apparatus of flagellin. The flagellum is required to cause a persistent disease in a murine model of infection [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=659, Percent_Identity=38.2397572078907, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76225; Mature: 76225

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAFSIAFSVLIL
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHH
MVALWIQRPLDFSAFPTVLLIATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEHHHHHHHHHHHHH
GGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDAIPGKQMAIDADLSSGLIDEK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCHH
EAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHH
DVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
FILGVMPGLPAFPFFLLGGAMAFVGIAVPRRQARQREADAAEAGKKQREAEEQEPNSVKA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEE
SLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQEYGFVIPEIKVTDDIALPPKS
ECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
YRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRRE
EEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHCCHHCCCCCCCCHHHHHHHHHC
GYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGL
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHCCHHHH
QAVLKLLLAERISIRNLHLILEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEE
VLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTEASAAIRKHFDNGERFVLVSS
HEECCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHCCCCCEEEEEEC
PEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKQTLGAVPAARLTGTGPMSVAKQEADVQQAAAKPFIKGKFLTGSDIGLAFSIAFSVLIL
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHH
MVALWIQRPLDFSAFPTVLLIATMMRLSLNIATTRVILTHGNEGYLAAGHVIHGFSQFVM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEEHHHHHHHHHHHHH
GGDFVIGLVVFAILIIVNFLVITKGATRIAEVGARFTLDAIPGKQMAIDADLSSGLIDEK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCHH
EAQRRRRELEEESSFFGSMDGASKFVRGDAIAGLIITAVNIFGGIVIGATRHGMDISQAA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHH
DVFTKLSVGDGLVTQIPALIVSLAAGLLVSKGGTRGSADQAIFGQLGAYPKALLIAALLL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
FILGVMPGLPAFPFFLLGGAMAFVGIAVPRRQARQREADAAEAGKKQREAEEQEPNSVKA
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEE
SLETNQIELCLGKQLSARLIASQEELAHRVNKMRRKFAQEYGFVIPEIKVTDDIALPPKS
ECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
YRIKIHGTAVASHELRVGEILVVLGERPVPSVPGEEVREPAFGMRAYSVPETFTADLRRE
EEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHCCHHCCCCCCCCHHHHHHHHHC
GYMTVDNLSVLLTHLSEIVRNNLAQLLSYKDMRILLDRLGPEYRKLLEDICPAHISYSGL
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHCCHHHH
QAVLKLLLAERISIRNLHLILEAIAEIAPLVRRPEMIVEHVRMRMAQQICGDLSDNGVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEE
VLRLGNRWDLVFHQSLKRDAKGEIVEFDIDPRLLEQFGTEASAAIRKHFDNGERFVLVSS
HEECCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHCCCCCEEEEEEC
PEARPYIRMIIERLFATLPVLSHVEIARGVEVKSLGAIS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]