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The map label for this gene is ffh [H]

Identifier: 163845404

GI number: 163845404

Start: 1266490

End: 1268061

Strand: Reverse

Name: ffh [H]

Synonym: BSUIS_B1304

Alternate gene names: 163845404

Gene position: 1268061-1266490 (Counterclockwise)

Preceding gene: 163845406

Following gene: 163845403

Centisome position: 90.52

GC content: 60.31

Gene sequence:

>1572_bases
ATGTTTGAAACACTTCAGGAGCGTCTTGGCTCCATCCTGAACGGCCTTACCGGACGCGGCGCTCTTTCAGAAAGCGACGT
GACGGCGGCGCTGCGCGAAGTGCGCCGTGCGCTGATCGAGGCGGATGTTTCGCTGGAAGTGGTTCGTTCCTTTACCGATC
GCGTGCGCGAAAAGGCGGTTGGTGCGGAAATCCTGAAAAGCATCAAGCCCGGCCAGATGGTCGTCAAAATCGTCCATGAC
GAGCTTGTCGAAATGCTGGGCACCGAAGGCGTTGCTATTGATCTGAACGCGCCTGCGCCCGTCGTCATCATGATGGTGGG
CTTGCAGGGTTCGGGCAAGACGACCACCACCGGCAAGATCGCCAAGCGCCTGACCGAGCGCCAGCGCAAACGCGTGCTGA
TGGCTTCGCTCGATACGCGCCGTCCGGCTGCGCAGGAGCAGCTTCGCCAGTTGGGGCTTCAGACCGGCGTGGATACGCTG
CCGATCATCGCAGGCCAGTCGCCGGTGGAGATCGCAAGGCGCGCCGTTCAGGCCGCAAAGCTTGGCGCGCATGATGTCGT
TATTCTCGATACGGCAGGCCGCACGCATATTGATGAGCCGCTGATGGTGGAAATGGCGGATATCCGCAAGGCCGCCAATC
CGCATGAAATCCTGCTCGTCGCCGATAGCCTCACCGGTCAGGACGCCGTCAATCTGGCGCGTAATTTCGATGAACGTGTG
GGCATTACCGGCATTGTGCTTACCCGCATGGATGGCGATGGACGCGGTGGCGCTGCTCTTTCCATGCGCGCCATCACCGG
CAAGCCGATCAAGCTGATCGCCACCGGCGAAAAGATGGATGCGCTGGAGGAATTCTATCCCAAGCGCATTGCCGACCGTA
TTCTCGGCATGGGCGACATTGTTTCGCTGGTCGAAAAGGCTGCCGAAAACATCGATGCGGAAAAAGCCGCGGCGATGGCC
AGGAAGATGCAGTCGGGCAAGTTCGATCTCAACGATCTTGCCGAGCAGCTCAAGCAGATGAAGAAGCTTGGCGGCATGGG
CGGCATCATGGGCATGATGCCCGGTATGGCCAAGATGAAGGATCAGGTGGCCGCTTCCGGTCTGGATGACAAGGTGTTCG
ACCGCCAGCTTGCCATCATCGGTTCGATGACCAAGGCCGAACGCGCCAATCCGGACCTTTTGAAGCATAGCCGCAAGCAG
CGCATAGCCAAAGGTTCGGGCACGAATGCCGCTGACATCAACAAGCTTCTCAAGATGCATCGCCAGATGGCCGACATGAT
GAAAATCATGGGCAAGGGCAAGGGCGGAATGATGAAGCAGATGATGGGTGGCCTTGCCAGCAAGATGGGGCTGGGCGGCC
TTGGCGGTGGTCTGGGTGGTATGCCTGACCTTTCCAAGATGGACCCGAAGCAACTTGAGGCGCTGGCCAAGCAGGCGGAA
GCAGCCGGACTCACCAAGGGTGGCCTTGGTGGCGGCTTGGGCGGTCTACCCGGCGGTGGCCTGTCCGGTTTGGGAGGCCC
GAAGCTTCCCGGCCTTGGCGGTGGCCTTCCGGGCCTGCCGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
GTGCCGTGACCCTATGGTTGCTTCCTGAACTGGCAGATGTGCGGGACGATCTATCCCGGACGAGCTTTCCATCTCATCCC
GGATAAGCCAAGGAAAATCG

Downstream 100 bases:

>100_bases
GCAGCATGAGCAACGAGCAGAACACCATACCCGCTGAGCTTCTGGCGTTGCGTGCATCGATCGACAATATCGACGCTGCC
CTCATTCATATGTTGGCCGA

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MFETLQERLGSILNGLTGRGALSESDVTAALREVRRALIEADVSLEVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELVEMLGTEGVAIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTERQRKRVLMASLDTRRPAAQEQLRQLGLQTGVDTL
PIIAGQSPVEIARRAVQAAKLGAHDVVILDTAGRTHIDEPLMVEMADIRKAANPHEILLVADSLTGQDAVNLARNFDERV
GITGIVLTRMDGDGRGGAALSMRAITGKPIKLIATGEKMDALEEFYPKRIADRILGMGDIVSLVEKAAENIDAEKAAAMA
RKMQSGKFDLNDLAEQLKQMKKLGGMGGIMGMMPGMAKMKDQVAASGLDDKVFDRQLAIIGSMTKAERANPDLLKHSRKQ
RIAKGSGTNAADINKLLKMHRQMADMMKIMGKGKGGMMKQMMGGLASKMGLGGLGGGLGGMPDLSKMDPKQLEALAKQAE
AAGLTKGGLGGGLGGLPGGGLSGLGGPKLPGLGGGLPGLPKKK

Sequences:

>Translated_523_residues
MFETLQERLGSILNGLTGRGALSESDVTAALREVRRALIEADVSLEVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELVEMLGTEGVAIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTERQRKRVLMASLDTRRPAAQEQLRQLGLQTGVDTL
PIIAGQSPVEIARRAVQAAKLGAHDVVILDTAGRTHIDEPLMVEMADIRKAANPHEILLVADSLTGQDAVNLARNFDERV
GITGIVLTRMDGDGRGGAALSMRAITGKPIKLIATGEKMDALEEFYPKRIADRILGMGDIVSLVEKAAENIDAEKAAAMA
RKMQSGKFDLNDLAEQLKQMKKLGGMGGIMGMMPGMAKMKDQVAASGLDDKVFDRQLAIIGSMTKAERANPDLLKHSRKQ
RIAKGSGTNAADINKLLKMHRQMADMMKIMGKGKGGMMKQMMGGLASKMGLGGLGGGLGGMPDLSKMDPKQLEALAKQAE
AAGLTKGGLGGGLGGLPGGGLSGLGGPKLPGLGGGLPGLPKKK
>Mature_523_residues
MFETLQERLGSILNGLTGRGALSESDVTAALREVRRALIEADVSLEVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELVEMLGTEGVAIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTERQRKRVLMASLDTRRPAAQEQLRQLGLQTGVDTL
PIIAGQSPVEIARRAVQAAKLGAHDVVILDTAGRTHIDEPLMVEMADIRKAANPHEILLVADSLTGQDAVNLARNFDERV
GITGIVLTRMDGDGRGGAALSMRAITGKPIKLIATGEKMDALEEFYPKRIADRILGMGDIVSLVEKAAENIDAEKAAAMA
RKMQSGKFDLNDLAEQLKQMKKLGGMGGIMGMMPGMAKMKDQVAASGLDDKVFDRQLAIIGSMTKAERANPDLLKHSRKQ
RIAKGSGTNAADINKLLKMHRQMADMMKIMGKGKGGMMKQMMGGLASKMGLGGLGGGLGGMPDLSKMDPKQLEALAKQAE
AAGLTKGGLGGGLGGLPGGGLSGLGGPKLPGLGGGLPGLPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=438, Percent_Identity=32.4200913242009, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI226371618, Length=374, Percent_Identity=33.4224598930481, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI23308697, Length=312, Percent_Identity=30.1282051282051, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI295424842, Length=312, Percent_Identity=30.1282051282051, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=34.5911949685535, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=52.2144522144522, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1789874, Length=254, Percent_Identity=37.4015748031496, Blast_Score=139, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17539958, Length=425, Percent_Identity=30.8235294117647, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=32.2147651006711, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=483, Percent_Identity=31.055900621118, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=27.1293375394322, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17647949, Length=445, Percent_Identity=30.7865168539326, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=30.8970099667774, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 55103; Mature: 55103

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFETLQERLGSILNGLTGRGALSESDVTAALREVRRALIEADVSLEVVRSFTDRVREKAV
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GAEILKSIKPGQMVVKIVHDELVEMLGTEGVAIDLNAPAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCHHHHH
AKRLTERQRKRVLMASLDTRRPAAQEQLRQLGLQTGVDTLPIIAGQSPVEIARRAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHH
LGAHDVVILDTAGRTHIDEPLMVEMADIRKAANPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGIVLTRMDGDGRGGAALSMRAITGKPIKLIATGEKMDALEEFYPKRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEKAAAMARKMQSGKFDLNDLAEQLKQMKKLGGMGGIMGMMPGMAKMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHH
DQVAASGLDDKVFDRQLAIIGSMTKAERANPDLLKHSRKQRIAKGSGTNAADINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RQMADMMKIMGKGKGGMMKQMMGGLASKMGLGGLGGGLGGMPDLSKMDPKQLEALAKQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AAGLTKGGLGGGLGGLPGGGLSGLGGPKLPGLGGGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFETLQERLGSILNGLTGRGALSESDVTAALREVRRALIEADVSLEVVRSFTDRVREKAV
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GAEILKSIKPGQMVVKIVHDELVEMLGTEGVAIDLNAPAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCHHHHH
AKRLTERQRKRVLMASLDTRRPAAQEQLRQLGLQTGVDTLPIIAGQSPVEIARRAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHH
LGAHDVVILDTAGRTHIDEPLMVEMADIRKAANPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGIVLTRMDGDGRGGAALSMRAITGKPIKLIATGEKMDALEEFYPKRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHH
VSLVEKAAENIDAEKAAAMARKMQSGKFDLNDLAEQLKQMKKLGGMGGIMGMMPGMAKMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHH
DQVAASGLDDKVFDRQLAIIGSMTKAERANPDLLKHSRKQRIAKGSGTNAADINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RQMADMMKIMGKGKGGMMKQMMGGLASKMGLGGLGGGLGGMPDLSKMDPKQLEALAKQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AAGLTKGGLGGGLGGLPGGGLSGLGGPKLPGLGGGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA