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The map label for this gene is qorA [H]

Identifier: 163845314

GI number: 163845314

Start: 1182744

End: 1183748

Strand: Reverse

Name: qorA [H]

Synonym: BSUIS_B1212

Alternate gene names: 163845314

Gene position: 1183748-1182744 (Counterclockwise)

Preceding gene: 163845319

Following gene: 163845313

Centisome position: 84.5

GC content: 61.79

Gene sequence:

>1005_bases
ATGATGGCCGAATTGCCCTCCCTGATGACCGCTATCGAAATCACCGAGCCCGGCGGCGCCTACATGCTGCGCCCGGCGCA
GCGCGCGGTGCCGGAGCCGAAGGAGGGTGAAATTCTGGTGCGGGTGCGCGCGGCCGGCGTCAACCGGCCCGACGTGTTGC
AGCGGCAGGGCCAATATGCACCCCCGCCGGGGGCTTCCGATATTCCGGGGCTGGAAATTGCCGGTGACATCGTCGCCCTT
GGGCATGGGGTGAAGCGGTTCAGGAAGGGCGATCAGGTCGTGGCCCTTTTGGCTGGCGGTGGCTATGCCGAATATGCCGT
GGTGCATGAAAGCAATGCGCTGCCGCTGCCATCGGGGTTTGGCTATATCGAAGCGGCGGCGATCCCGGAAACCTTCTTCA
CCGTCTGGCATAATGTTTTCGAGCGCGGGGGGCTTAAGGAGGGAGAGGTTTTTCTGGTTCATGGCGGCTCGTCCGGTATC
GGCACGACTGCGATCCAGCTTGCCAAGGCTTTTGGCGCGACGGTCATCACCACCGCAGGATCGAAGGAAAAATGCGACGC
CTGCGTGAAGCTTGGCGCAGACCGAGCCATCAATTATCACGAGGAGGATTTTGTCGCGGTTGTGAAAGAGATGACCGGCG
GCAAGGGCGTGGATGTGATTCTGGACATGGTGGGTGGCGATTATGTCGAGCGCAATTACAAGGCTGCCGCCGAGGATGGG
CGCATCGTGCAGATTGCTTTCCTGAACGGGGCCAAGGCAACGGCCAATTTCGCGATTCTGATGACCAAGCGGCTGACCCA
TACCGGCTCCACGCTGCGCCCGCGCCCGGTGGCGTTCAAGGCGGGTATCGCCAGAGAACTGGAGGCCAAGGTTTGGCCGC
TTCTGGCGCAGCGCCGTGTCGCGCCTGTGATGGATATGATTTTTTCGCTGAAAGATGCCTGGCGGGCGCATGAGCGCATG
GAGGAGGGGCGCCATATCGGCAAGATCGTGCTGGACATAGCGTAG

Upstream 100 bases:

>100_bases
TAACAACTTTCTTGCATCCGGCGATGGGCATTTTTGCGGCCTTTATTGGACGGGCCGATGTCCATATAAAAATCAAGAAA
TATGAACGGAGTTTTTGACA

Downstream 100 bases:

>100_bases
AATATCGACATAGAGCCATTCTTGCTCTGGCGACAAAAAACCTATATACAAGCCATGATTTCCCGGAAATTGTGGTTTTG
CCCACGTCCCGCGCCACCGG

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MMAELPSLMTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVAL
GHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGI
GTTAIQLAKAFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDG
RIVQIAFLNGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERM
EEGRHIGKIVLDIA

Sequences:

>Translated_334_residues
MMAELPSLMTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVAL
GHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGI
GTTAIQLAKAFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDG
RIVQIAFLNGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERM
EEGRHIGKIVLDIA
>Mature_334_residues
MMAELPSLMTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDIPGLEIAGDIVAL
GHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGI
GTTAIQLAKAFGATVITTAGSKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDG
RIVQIAFLNGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIFSLKDAWRAHERM
EEGRHIGKIVLDIA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=40, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=40, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI194239674, Length=338, Percent_Identity=30.7692307692308, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI13236495, Length=338, Percent_Identity=30.7692307692308, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI24308257, Length=347, Percent_Identity=29.971181556196, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI194239676, Length=217, Percent_Identity=35.0230414746544, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=26.2135922330097, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI28557745, Length=319, Percent_Identity=33.8557993730408, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=28.125, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI47519420, Length=332, Percent_Identity=27.4096385542169, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=321, Percent_Identity=35.202492211838, Blast_Score=147, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17507255, Length=333, Percent_Identity=27.6276276276276, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=316, Percent_Identity=26.8987341772152, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=200, Percent_Identity=26.5, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71987554, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=29.6511627906977, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=360, Percent_Identity=25, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=24.5508982035928, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=300, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581345, Length=300, Percent_Identity=27.3333333333333, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19920632, Length=300, Percent_Identity=27.3333333333333, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI221330659, Length=300, Percent_Identity=27.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550423, Length=156, Percent_Identity=27.5641025641026, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35826; Mature: 35826

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAELPSLMTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYA
CCCCHHHHHEEEEEECCCCCEEECCHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
PPPGASDIPGLEIAGDIVALGHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGF
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
GYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAKAFGATVITTAG
CCEEEHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDG
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCHHHCCCC
RIVQIAFLNGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRV
CEEEEEEECCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
APVMDMIFSLKDAWRAHERMEEGRHIGKIVLDIA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure
MMAELPSLMTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYA
CCCCHHHHHEEEEEECCCCCEEECCHHHCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
PPPGASDIPGLEIAGDIVALGHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGF
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
GYIEAAAIPETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAKAFGATVITTAG
CCEEEHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SKEKCDACVKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDG
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCHHHCCCC
RIVQIAFLNGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRV
CEEEEEEECCCCCCCCEEEEEEEHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
APVMDMIFSLKDAWRAHERMEEGRHIGKIVLDIA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]