Click here to switch to the map view.

The map label for this gene is aaeA [H]

Identifier: 163844887

GI number: 163844887

Start: 726596

End: 727462

Strand: Reverse

Name: aaeA [H]

Synonym: BSUIS_B0750

Alternate gene names: 163844887

Gene position: 727462-726596 (Counterclockwise)

Preceding gene: 163844888

Following gene: 163844886

Centisome position: 51.93

GC content: 58.25

Gene sequence:

>867_bases
ATGAAAAAGCTCCTTGCACATTCCGGCCGGGTTTTTCTCACCCTCGTCATGGTTGTTATGGCGGGGCTGCTCGGCTGGCA
TCTCTGGGATTATTACATGAATGCGCCGTGGACCCGTGACGGCAAAATCCGTGCCGATGTGGTGCGCATTGCGCCCGATG
TCTCGGGCCTTGTGAGCGAGGTTCTGGTGCATGACAACCAGACGGTCCATAAAGGCGATGTGATTTTCCGCATCGACCAG
GCGCGCTACAAGCTTGCTTTGCAGACTGCTGAGGCCAAGGCTGACAGCAGCAAGGCAGCACTGGACATGGCCAATCGTGA
TCTTGTCCGCTATCGCCAGCTCAACGATACGACCGTGACGCGCCAGAAACTGGAACAGGTAGAAACCGCAGCCCAGCAGG
CAGAGGCCGCCCACCGCCAGGCCGAACTCGACCGCGATCTGGCTGCGCTTAATATGGAGCGTTCGTCTATCAAGGCTCCG
GTCAATGGCGTTATCACCAATTTCTCGCTTCAGCCGGGCGATTATGTTTCGGCGGGTTCGGCCGTTACGGCGCTGGTCGA
TACGGATTCCTATTATGTCTCCGGTTATTTTGAGGAAAACAAGCTGGAGCGTATCCATATCGGTGATCCGGTGGTGGTCG
ATGTGATGGGCAGCAAGGTGCAGCTCAAGGGTAAGGTGGAAGGTATTGCGGGCGGCATCGAGGATCGCGAGCGCAGCGAT
TCCCAAAGCCTGCTCGCCAATGTCTCGCCGACGTTCAACTGGGTGCGCCTTGCGCAGCGCGTGCCGGTGCGTGTGAAACG
GGAAGATGTGCCGCAAGGCATCCATCTGGTGGCAGGCCGCACGGTGAGCGTTTCGGTGGTGGATTGA

Upstream 100 bases:

>100_bases
TGCATTTCTACCGTTTTGTGTGGCATCGCCCGCTTTTCGATGCCGCCATGTATTTCTGCATTCTCGGCGTTGCTGCCGTC
CTCTTGAATGGAATCCCCCT

Downstream 100 bases:

>100_bases
TGGCCCGGCCGCGCCACTGGCGGGCATGCTACCAGAATAGCTCCGGTTAAAACGGTATCGCCTCTCTTATCTTGGGGGCA
AGGGAATGGCTGCCGCGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKREDVPQGIHLVAGRTVSVSVVD

Sequences:

>Translated_288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKREDVPQGIHLVAGRTVSVSVVD
>Mature_288_residues
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSEVLVHDNQTVHKGDVIFRIDQ
ARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVTRQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAP
VNGVITNFSLQPGDYVSAGSAVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
SQSLLANVSPTFNWVRLAQRVPVRVKREDVPQGIHLVAGRTVSVSVVD

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=279, Percent_Identity=39.7849462365591, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789637, Length=286, Percent_Identity=37.7622377622378, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1790519, Length=286, Percent_Identity=29.7202797202797, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789041, Length=299, Percent_Identity=25.4180602006689, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788711, Length=312, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790024, Length=274, Percent_Identity=25.9124087591241, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082036, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 31820; Mature: 31820

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHH
VLVHDNQTVHKGDVIFRIDQARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVT
HHHCCCCEEECCCEEEEECCHHEEEEEEHHHHCCCCCHHHHHHHCCHHHHHHHCCCHHHH
RQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAPVNGVITNFSLQPGDYVSAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCCCC
AVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
EEEEEEECCCEEEEEEEECCCCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCHHCCCC
SQSLLANVSPTFNWVRLAQRVPVRVKREDVPQGIHLVAGRTVSVSVVD
HHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCEEEEECCEEEEEEEC
>Mature Secondary Structure
MKKLLAHSGRVFLTLVMVVMAGLLGWHLWDYYMNAPWTRDGKIRADVVRIAPDVSGLVSE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHH
VLVHDNQTVHKGDVIFRIDQARYKLALQTAEAKADSSKAALDMANRDLVRYRQLNDTTVT
HHHCCCCEEECCCEEEEECCHHEEEEEEHHHHCCCCCHHHHHHHCCHHHHHHHCCCHHHH
RQKLEQVETAAQQAEAAHRQAELDRDLAALNMERSSIKAPVNGVITNFSLQPGDYVSAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCCCCCCC
AVTALVDTDSYYVSGYFEENKLERIHIGDPVVVDVMGSKVQLKGKVEGIAGGIEDRERSD
EEEEEEECCCEEEEEEEECCCCCEEECCCCEEEEECCCEEEEEEEECCCCCCCCHHCCCC
SQSLLANVSPTFNWVRLAQRVPVRVKREDVPQGIHLVAGRTVSVSVVD
HHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA