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The map label for this gene is glmU [H]

Identifier: 163844735

GI number: 163844735

Start: 566511

End: 567875

Strand: Reverse

Name: glmU [H]

Synonym: BSUIS_B0579

Alternate gene names: 163844735

Gene position: 567875-566511 (Counterclockwise)

Preceding gene: 163844736

Following gene: 163844734

Centisome position: 40.54

GC content: 58.97

Gene sequence:

>1365_bases
ATGACTGACCGTACATGCCTTTCCATCGTGCTTGCCGCTGGCGAAGGCACGCGCATGAAATCGAATTTGCCGAAAGTGCT
GCATCGCGTGGCAGGCCTGCCGCTGGTATGCCATGTGGTCAATGCGGTGCGGGGCACCGGCAAAAGCGACGTTGCGCTTG
TGGTCGGCCGCGGTGCGGAAGACGTGCGCAGCGCGGTGGAGAAAATCGCCGGGCCGGTTTCGGCCTTCGAGCAGAAGGAA
AGGCTTGGCACGGCGCACGCTGTTCTTGCCGCGCGCGAAGCCATTGCGCGTGGCTATGACGACCTTCTGATCGTTTTTGG
CGATACGCCGCTGATCGAGGCGCAATCGCTTCTGGCCGCGCGTGAGCGGCTGGCGCAAGGGGCAGACCTTGTCGTGATCG
GTTTTCGCCCGGCCAGCCCGCACGGCTATGGCCGCCTGATCGAAGAAGGCGGGCAGCTTGTCGCGATTATCGAGGAAAAA
GAGGCGACCGACGAACAGAAGAAAATCGGCTTCTGCAATGGCGGCCTCATGGCGTTGCGCGGACAACACGCGCTGGCGCT
GCTCGATGCCGTTGGCAATGACAATGCGAAGGGCGAATATTACCTCACTGATATTGTTGCAATCGCGCACGGCAAGGGGC
TGAACGTCACGGCCATCGAAGTGCCGGTCGATAATGTCATCGGCATCAACAATCGCGCCGAACTGGCCGAGGCCGAAACC
ATCTGGCAAAACCGCAAGCGTCGGGAGCTTATGCTTTCCGGTGTGACGCTGATCGCACCTGAAACAGTCTTCTTTTCATA
TGACACGGTGATTGAGCCCGATGTTGTGATCGAACCGAACGTCTTCTTCGGCCCTTCGGTGCATGTCGCATCGGGTGCGC
TCATCCATTCCTTCTCGCATCTGGAAGGGGCGCAGGTGGGTGAAAAGGCCGAGATCGGGCCATTTGCCCGGCTTCGCCCC
GGCGCCGATCTGGCGGAAAAATCCAAGGTCGGCAATTTCTGCGAAGTAAAGAACGCGAAGGTTGGCAAGGGCGCAAAGAT
CAATCACCTGACCTATATTGGCGATGCGGTCATCGGCGCTTCCAGCAATATTGGTGCGGGCACGATCACCTGTAATTATG
ATGGCTACAACAAGTTCAAGACCATCATCGGCGACAATGCCTTTATCGGCTCCAACAGTTCGCTCGTTGCGCCGGTGGAA
ATCGGCGACAACGCCTATATCGCCTCCGGCAGCGTCATCACGGCAGACGTTCCAGCCGATGCGCTGGCCCTTGGCCGCGC
CCGTCAGGAGACGAAGGAAGGCCGGGCAAAGATCCTGCGGGAGAAGTATGCCGCCATCAAAGCGGCTAAAAGCGTTTCAA
AGTAA

Upstream 100 bases:

>100_bases
ACTGGGGCGCTTGGGCTAAAACTGTGCCAGCAATCCGTAAGCTTCCATATACGCTTTGATGCTATGTGCGTATAAGTCTT
CAAAAAATTCGGACAACACC

Downstream 100 bases:

>100_bases
TTGAACGGATGGAGGCTTTTACGGCAACAAGTCCGGGTGCCGTAAAGCTTTCAAGCCTTTAAAGCCTGCAATAGGCCAGA
CTTTCTATTTGGAGCATGCA

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKE
RLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEK
EATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAET
IWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRP
GADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVE
IGDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK

Sequences:

>Translated_454_residues
MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKE
RLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEK
EATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAET
IWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRP
GADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVE
IGDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK
>Mature_453_residues
TDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKER
LGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKE
ATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAETI
WQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRPG
ADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEI
GDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=460, Percent_Identity=41.304347826087, Blast_Score=341, Evalue=6e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47935; Mature: 47804

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAE
CCCHHEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHH
DVRSAVEKIAGPVSAFEQKERLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
RERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKEATDEQKKIGFCNGGLMALR
HHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHCEEECCCEEEEC
GQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAET
CCHHEEEEEHHCCCCCCCCEEEEEEEEEECCCCCEEEEEEECCCCEECCCCCHHHHHHHH
IWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSH
HHHHHHHHHHHHCCEEEEECCEEEEEECCEECCCEEECCCEEECCCCCHHCCHHHHHHHH
LEGAQVGEKAEIGPFARLRPGADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGA
CCCCCCCCCCCCCCCHHCCCCCCHHHHHCCCCEEECCCCCCCCCCEEEEEEEECCEEECC
SSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEIGDNAYIASGSVITADVPAD
CCCCCCEEEEEECCCCHHHHHHCCCCEEECCCCCEEEEEEECCCEEEECCCEEEECCCHH
ALALGRARQETKEGRAKILREKYAAIKAAKSVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAE
CCHHEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHH
DVRSAVEKIAGPVSAFEQKERLGTAHAVLAAREAIARGYDDLLIVFGDTPLIEAQSLLAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
RERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKEATDEQKKIGFCNGGLMALR
HHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHCEEECCCEEEEC
GQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAET
CCHHEEEEEHHCCCCCCCCEEEEEEEEEECCCCCEEEEEEECCCCEECCCCCHHHHHHHH
IWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSH
HHHHHHHHHHHHCCEEEEECCEEEEEECCEECCCEEECCCEEECCCCCHHCCHHHHHHHH
LEGAQVGEKAEIGPFARLRPGADLAEKSKVGNFCEVKNAKVGKGAKINHLTYIGDAVIGA
CCCCCCCCCCCCCCCHHCCCCCCHHHHHCCCCEEECCCCCCCCCCEEEEEEEECCEEECC
SSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEIGDNAYIASGSVITADVPAD
CCCCCCEEEEEECCCCHHHHHHCCCCEEECCCCCEEEEEEECCCEEEECCCEEEECCCHH
ALALGRARQETKEGRAKILREKYAAIKAAKSVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA