Click here to switch to the map view.

The map label for this gene is bioD [H]

Identifier: 163844653

GI number: 163844653

Start: 473515

End: 474153

Strand: Reverse

Name: bioD [H]

Synonym: BSUIS_B0490

Alternate gene names: 163844653

Gene position: 474153-473515 (Counterclockwise)

Preceding gene: 163844654

Following gene: 163844652

Centisome position: 33.85

GC content: 59.31

Gene sequence:

>639_bases
ATGAATTCCCGTTTGATCGTTACCGGCACGGATACTGGCATCGGCAAGACCGTGTTCAGCGCGGCGCTCTGCCATGCCTT
GGGGGCCGCCTATTGGAAACCCGTTCAATCGGGCCTTGAAGAAGAAACCGACAGCGAGATCGTCGCGCGTCTGGCACAGG
CTTCGCCTCAGCGTATCCTGCCGGAGGCATGGCGCCTGAATACACCAGCCTCGCCGCATCTTTCCGCCCGCCTCGATGGC
GTCGAGATCCGGCCGGAAGAGATGCATATTCCCGCAACCTCGCTGCCGCTCGTCATCGAGGGCGCAGGCGGATTGCTGGT
GCCATTAAACGATAAAACCCTCTTCGCAGATCTTTTCGCAATCTGGCGCATTCCCGCCATTCTTTGCGCGCGCGCAGCCC
TTGGCACCATCAATCATACACTCCTCTCGCTGGAAGCCATGCGCAGCCGCGATATTCCGGTCCTGGGTGTCGCCTTCATC
GGTGAAGCGAACGAAGACACGGAAACCACGATCGCCCATCTTGGCCGGGTGAAACGGTTGGGCCGCCTGCCGCTTCTCGA
TGATCTTTCGCCGGAAAAGCTGCATCACAGCTTTGCCCGGAATTTCCACATTGACGATTTCGCAGGAGTGGCACGATGA

Upstream 100 bases:

>100_bases
GCACGGCGCGCCTGCGCATTTCCATCACGCTCAATGTCGGTCTCGCCGACATCGACCGCATGGTTGAAACGCTTTCCTAC
GCGACTTTTAGAGAAGCAGC

Downstream 100 bases:

>100_bases
ACCCGAACACCTCGCCCGTCTGGCACCCCTTTACCCAGCACAGGCTGGAGCCGCGCCCGGACCGGATCGTCCGCACCGAA
GGCGCCTATCTTTTTCGTGA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDG
VEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFI
GEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR

Sequences:

>Translated_212_residues
MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDG
VEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFI
GEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
>Mature_212_residues
MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDG
VEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFI
GEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=217, Percent_Identity=30.8755760368664, Blast_Score=78, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324385, Length=191, Percent_Identity=36.1256544502618, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22989; Mature: 22989

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRIL
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCC
PEAWRLNTPASPHLSARLDGVEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFA
CHHHCCCCCCCCCCHHCCCCCEECHHHEECCCCCCCEEEECCCCEEEECCCCHHHHHHHH
IWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFIGEANEDTETTIAHLGRVKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
GRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure
MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRIL
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCC
PEAWRLNTPASPHLSARLDGVEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFA
CHHHCCCCCCCCCCHHCCCCCEECHHHEECCCCCCCEEEECCCCEEEECCCCHHHHHHHH
IWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFIGEANEDTETTIAHLGRVKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
GRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
CCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA