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The map label for this gene is agcS [H]

Identifier: 163844646

GI number: 163844646

Start: 467076

End: 468509

Strand: Reverse

Name: agcS [H]

Synonym: BSUIS_B0483

Alternate gene names: 163844646

Gene position: 468509-467076 (Counterclockwise)

Preceding gene: 163844647

Following gene: 163844645

Centisome position: 33.44

GC content: 55.93

Gene sequence:

>1434_bases
ATGGCGACAATCATTGATTTTCTGAATAATGTTTTCTGGAATTATGTTCTAGTTTATGGGCTGCTTGCAGTCGGACTTTT
CTTTACAATCCGGCTGAAATTTGTCCAGTTCGTTCATTTTCCTGAACTTTTCAGAGTCGTTTTTGCCGCCGGCAGGCGTG
ATGAAGCCGGTATTTCTCCGTTTCAGGCTCTCACCATCAGCATTGCCTCGCGCGTTGGTACCGGCAACATTACGGGCGTT
GCTGTTGCACTCTATCTTGGCGGGCCCGGCGCAATTTTCTGGATGTGGATAGTGGCGCTTGTAGGGCTTGCAACCGCCTA
TTCGGAAAGTGCGCTGGCGCAACTTTATAAAATCCGCAGTCAGGATGGCCAGTATCGCGGCGGCCCTGCCTTCTATATTG
CGTGCGGCCTCGGCCTGCCATGGGCTGGCGCCTTGTTTTCCATCTGCCTCATCCTTTCCTTCGGCCTTGTTTTCAATGCG
GTGCAGGCCAACGCCATTGCCGATTCCATGGTTATGGCTTTCAACATGCCCAAGCTTGGCACGGGTATCGTGCTCGCCAT
TCTTTCGGGCGTGGTGATTTTCGGCGGTATCCGCCAGATCGCGCGCGTGGCTGAAGTGGTCGTGCCTTTCATGGCCTTCG
CCTATATCCTGATGGCAATCTGCATTCTTGCAATCAACTTCCAAGCGGTCCCGTCGACAATCGCACTGATCTTCTCCAGT
GCCTTTGGCCTGCATGAAGCAGTGGGCGGTGTGACGGGCGGCATTACCGCGGCCATGCTCAATGGCGTAAAGCGCGGTCT
TTTCTCCAACGAGGCGGGCATGGGTTCTGCCCCCAATACTGCCGCCGTGGCGACACCTGCGCCGCACCATCCCTCCTCGC
AGGGCTTCGTACAATCGCTTGGCGTCTTCATCGATACGATTCTGGTCTGCACGGCGACGGCGATCATGATCCTCTTGTCC
GGCATTCTGGAGCCCGGTTCAGGCCTCGCCGGCACGCAACTCACCCAAATGGCAATGACCCATCATATCGGTGACGTGGG
CGTTTATTTCATCGCCGCCGCGATCTTCTTCTTCGCCTTCACCTCCATCATCGGCAATTATTCCTATGCGGAAAGCGCCA
TGACCTTTCTGGGGCTTGGCGGCAAGGTGCCGATCACCATTCTGCGCTGCGCGCTTCTCGCCATGGTCGTCTGGGGCGCT
TATGAAAGCATCCATACCGTGTTTGACGCGGCCGATGCCTCGATGGGCCTGATGGCGACGATCAACCTGATTGCCATCGT
TCTGCTTTCGGGAACGGTGAAGAAGCTCACGGTTGACTATTTCGCGCAGAGGCGCGCGGGGCAGGTTCCCACCTTCCACG
CCGCCGATTACCCGGAACTGCAAGGCCAGATCGACATGGAAATCTGGTCTGAACAGAATACGACGAACAAGTAA

Upstream 100 bases:

>100_bases
CCAGCGCGCGCGTTCCACATTATCAAAATCAAAATTTCCGTCAGGACTCGACAGAAGCCCATGATTATCGTTAAACCGCC
CCACCAAACGAGGATTTTTC

Downstream 100 bases:

>100_bases
CGTCATCGCAATTTCCATAGGCTACCTCCAGCCGACGGAACCAAGCATGCAACCGCGCGTTTCCCTTCATGCCCCGCCTG
TGCTTCGTGCAACGGCGGGC

Product: amino acid carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MATIIDFLNNVFWNYVLVYGLLAVGLFFTIRLKFVQFVHFPELFRVVFAAGRRDEAGISPFQALTISIASRVGTGNITGV
AVALYLGGPGAIFWMWIVALVGLATAYSESALAQLYKIRSQDGQYRGGPAFYIACGLGLPWAGALFSICLILSFGLVFNA
VQANAIADSMVMAFNMPKLGTGIVLAILSGVVIFGGIRQIARVAEVVVPFMAFAYILMAICILAINFQAVPSTIALIFSS
AFGLHEAVGGVTGGITAAMLNGVKRGLFSNEAGMGSAPNTAAVATPAPHHPSSQGFVQSLGVFIDTILVCTATAIMILLS
GILEPGSGLAGTQLTQMAMTHHIGDVGVYFIAAAIFFFAFTSIIGNYSYAESAMTFLGLGGKVPITILRCALLAMVVWGA
YESIHTVFDAADASMGLMATINLIAIVLLSGTVKKLTVDYFAQRRAGQVPTFHAADYPELQGQIDMEIWSEQNTTNK

Sequences:

>Translated_477_residues
MATIIDFLNNVFWNYVLVYGLLAVGLFFTIRLKFVQFVHFPELFRVVFAAGRRDEAGISPFQALTISIASRVGTGNITGV
AVALYLGGPGAIFWMWIVALVGLATAYSESALAQLYKIRSQDGQYRGGPAFYIACGLGLPWAGALFSICLILSFGLVFNA
VQANAIADSMVMAFNMPKLGTGIVLAILSGVVIFGGIRQIARVAEVVVPFMAFAYILMAICILAINFQAVPSTIALIFSS
AFGLHEAVGGVTGGITAAMLNGVKRGLFSNEAGMGSAPNTAAVATPAPHHPSSQGFVQSLGVFIDTILVCTATAIMILLS
GILEPGSGLAGTQLTQMAMTHHIGDVGVYFIAAAIFFFAFTSIIGNYSYAESAMTFLGLGGKVPITILRCALLAMVVWGA
YESIHTVFDAADASMGLMATINLIAIVLLSGTVKKLTVDYFAQRRAGQVPTFHAADYPELQGQIDMEIWSEQNTTNK
>Mature_476_residues
ATIIDFLNNVFWNYVLVYGLLAVGLFFTIRLKFVQFVHFPELFRVVFAAGRRDEAGISPFQALTISIASRVGTGNITGVA
VALYLGGPGAIFWMWIVALVGLATAYSESALAQLYKIRSQDGQYRGGPAFYIACGLGLPWAGALFSICLILSFGLVFNAV
QANAIADSMVMAFNMPKLGTGIVLAILSGVVIFGGIRQIARVAEVVVPFMAFAYILMAICILAINFQAVPSTIALIFSSA
FGLHEAVGGVTGGITAAMLNGVKRGLFSNEAGMGSAPNTAAVATPAPHHPSSQGFVQSLGVFIDTILVCTATAIMILLSG
ILEPGSGLAGTQLTQMAMTHHIGDVGVYFIAAAIFFFAFTSIIGNYSYAESAMTFLGLGGKVPITILRCALLAMVVWGAY
ESIHTVFDAADASMGLMATINLIAIVLLSGTVKKLTVDYFAQRRAGQVPTFHAADYPELQGQIDMEIWSEQNTTNK

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=472, Percent_Identity=42.5847457627119, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 50542; Mature: 50411

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIIDFLNNVFWNYVLVYGLLAVGLFFTIRLKFVQFVHFPELFRVVFAAGRRDEAGISP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
FQALTISIASRVGTGNITGVAVALYLGGPGAIFWMWIVALVGLATAYSESALAQLYKIRS
HHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QDGQYRGGPAFYIACGLGLPWAGALFSICLILSFGLVFNAVQANAIADSMVMAFNMPKLG
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TGIVLAILSGVVIFGGIRQIARVAEVVVPFMAFAYILMAICILAINFQAVPSTIALIFSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AFGLHEAVGGVTGGITAAMLNGVKRGLFSNEAGMGSAPNTAAVATPAPHHPSSQGFVQSL
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHH
GVFIDTILVCTATAIMILLSGILEPGSGLAGTQLTQMAMTHHIGDVGVYFIAAAIFFFAF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIIGNYSYAESAMTFLGLGGKVPITILRCALLAMVVWGAYESIHTVFDAADASMGLMAT
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
INLIAIVLLSGTVKKLTVDYFAQRRAGQVPTFHAADYPELQGQIDMEIWSEQNTTNK
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEECCCCCCCC
>Mature Secondary Structure 
ATIIDFLNNVFWNYVLVYGLLAVGLFFTIRLKFVQFVHFPELFRVVFAAGRRDEAGISP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
FQALTISIASRVGTGNITGVAVALYLGGPGAIFWMWIVALVGLATAYSESALAQLYKIRS
HHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QDGQYRGGPAFYIACGLGLPWAGALFSICLILSFGLVFNAVQANAIADSMVMAFNMPKLG
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TGIVLAILSGVVIFGGIRQIARVAEVVVPFMAFAYILMAICILAINFQAVPSTIALIFSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AFGLHEAVGGVTGGITAAMLNGVKRGLFSNEAGMGSAPNTAAVATPAPHHPSSQGFVQSL
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHH
GVFIDTILVCTATAIMILLSGILEPGSGLAGTQLTQMAMTHHIGDVGVYFIAAAIFFFAF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIIGNYSYAESAMTFLGLGGKVPITILRCALLAMVVWGAYESIHTVFDAADASMGLMAT
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
INLIAIVLLSGTVKKLTVDYFAQRRAGQVPTFHAADYPELQGQIDMEIWSEQNTTNK
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969507; 9384377; 7710280 [H]