Click here to switch to the map view.

The map label for this gene is oxyR [H]

Identifier: 163844530

GI number: 163844530

Start: 336646

End: 337599

Strand: Reverse

Name: oxyR [H]

Synonym: BSUIS_B0359

Alternate gene names: 163844530

Gene position: 337599-336646 (Counterclockwise)

Preceding gene: 163844541

Following gene: 163844529

Centisome position: 24.1

GC content: 55.66

Gene sequence:

>954_bases
ATGTTTACAGTCCGTCAAATACGCTATTTCGATGCGCTTGCCTCTACCCTGCATTTTCGCAAGGCCGCCGAACTGGCCCA
TGTTTCACAACCAGCACTCTCCGCCCAGATTGCAGAAATGGAGGCAATCGCGGGTGCACCGCTTTTCGAGCGCTCGCAGC
GGCAGGTTATCATGACCGAGCTTGGAAAGCACCTTTATCCTGGCATCAAGGCCATCCTGCGCGAATTACAGAAGCTGGAG
GAAATAGCCGCACAAAGCCGTGGCGTGCTGCAAACGGGCATAAAGCTCGGGATCATTCCCACCGTCGCGCCCTATCTCGT
GCCGGTTCTCATTCCCCTGCTGCACGAACAGCATCCATCTTTCCGCCTACAGTTGCGCGAGAGCGTCACGGCAAAATTGC
TGGAAGAACTGCACGCTGGCGATCTGGACACCATTGTTGCCGCCTTGCCGATCGATGACGAGAAGCTTAGCCACCAGAAG
CTTTTCGACGACCGTTTTCTCATCGCCACCTCCACCAACGACCATACGGTTCTCGCCTCGCCGATGACGCAGAACCATGC
CGCGCTGGAACGACTTCTGCTGCTGGAGGAAGGCCATTGCATGCGCGACCAGGCGCTCGCCGTTTGCACCCTGCCCTCCC
AGCGGCAACTGGTGAAATACGGCGCAACCAGCATGAGCACGCTTTTGCAGATGGTCAGCCATGGCATGGGGCTGACGCTG
ATCCCCGAAATTGCCGTTCGTGCCGAAGCGCGCAGCAACCATATGCGCATCGTGCCTTTCGAGGGGGAACAACCCAAGCG
CGAGATTGCACTTTTCTGGCGGCGGCAAAGCATGCGCGGGAAAGGTTTTCGAGCGCTCGCCGAATGTATTGCAGAAAGTG
CTAATAAACTAAAGATAGATCCTTCCAAGATTGATACTTTATTGGATAACCCTTCTACCCCTTCATATTCTTAA

Upstream 100 bases:

>100_bases
GAAACATCACACCGGGGCGAAACCATTTGTCTCAATTAGACCTATTCCAATAATAATCTCCAATTGCTTTTTTTGTTATT
ATTGATAAGATTTTCCTATC

Downstream 100 bases:

>100_bases
TGTTACATTAAGCCTGAAAGTATAGCCCCCAAATGTTTTGATTCCAAAACACATATATGGAGGGAATAATGAGGTGGTCC
GATGTGGGGATCTATGGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDTIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKGFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS

Sequences:

>Translated_317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDTIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKGFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS
>Mature_317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDTIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKGFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=37.0242214532872, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1788887, Length=283, Percent_Identity=25.7950530035336, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=28.5123966942149, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787601, Length=168, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=28.7162162162162, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693105, Length=257, Percent_Identity=24.124513618677, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=28.968253968254, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367136, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081904, Length=303, Percent_Identity=23.4323432343234, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790783, Length=258, Percent_Identity=26.3565891472868, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=309, Percent_Identity=22.6537216828479, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35318; Mature: 35318

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGKHLYPGIKAILRELQKLEEIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
FRLQLRESVTAKLLEELHAGDLDTIVAALPIDDEKLSHQKLFDDRFLIATSTNDHTVLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHCCCCEEEEECCCCCEEEEC
PMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEEE
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKGFRALAECIAESANKLKID
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEECC
PSKIDTLLDNPSTPSYS
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGKHLYPGIKAILRELQKLEEIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
FRLQLRESVTAKLLEELHAGDLDTIVAALPIDDEKLSHQKLFDDRFLIATSTNDHTVLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHCCCCEEEEECCCCCEEEEC
PMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEEE
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKGFRALAECIAESANKLKID
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEECC
PSKIDTLLDNPSTPSYS
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]