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The map label for this gene is virB6

Identifier: 163844262

GI number: 163844262

Start: 61014

End: 62057

Strand: Reverse

Name: virB6

Synonym: BSUIS_B0068

Alternate gene names: 163844262

Gene position: 62057-61014 (Counterclockwise)

Preceding gene: 163844263

Following gene: 163844261

Centisome position: 4.43

GC content: 55.56

Gene sequence:

>1044_bases
ATGGTTAATCCTGTAATCTTTGAGTTCATCGGCACTTCGATCCACAACCAGTTGAACAATTACGTGACTATGGTGGCATC
CAACACCATGAATATGATTGCCACGACTGCTGTCCTCGCCGGTGGCCTCTACTATACCGCCATGGGCATATTGATGTCTG
TGGGGCGGATCGAAGGGCCGTTTTCGCAACTCGTCATAAGCTGTATTAAATTCATGCTGATTGCTGCTTTTGCGCTCAAT
ATCAGCACCTATTCGGAGTGGGTGATCGATACGGTGCACAACATGGAGTCCGGATTTGCCGACGCCTTTGCCGGCAATCA
CGGCACCCCTTCCAGCACGATCTACCAGACCCTCGACAATTCGTTGGGCAAGGGGTGGAACATCGCAGCCATGCTCTTTG
AGAAAGGCGATAATCGCGGCCTGACCCAGATCGTGCAGGGCTTTTCAGAACTGTTACTGTCATTCCTGGTAGCCGGCTCA
ACGCTTATCCTTGCAGGCCCGACTGGTGCGATGATCGTCGCAACCAATGCGGTGATCGCGATCCTGCTCGGAATCGGCCC
TCTCTTCATCCTCGCCCTTGGCTGGGCGCCGACAAGGGGCTTCTTCGATCGCTGGTTCGGGGCCATCGTCACATCGATCC
TTCAGGTCGCGCTTTTGTCGGCCGTGCTATCTATATCGAGTGCAATCTTCAGCCGCATGGTGGCGGCCATCAATTTGGCT
TCCGCAACACAAAGCACGCTCTTTTCCTGCCTCTCACTGACCGCTGTAACGATTGTCATGCCGTATATGATGTACAAGGT
CTATGAATACGGTGGCATCCTGGGCAGCAGCATATCGGCGGCCACGATCTCCCTCGGCTCACTTGCAGTCAATACCGCGA
CATCTGGTGGTGGCGCTATGACGAGCATATTCAGCGGATCATCCGGCGGCGGGGGTTCCGGCTCGGCGAAGGCGGGCGGG
GAAAGCAGTTATTCGGCTGGTGGCAACGCCATGTGGAGCCCGGCTTACCGGCAACACGTGCTCGGCCAGTTCAACAGGGA
TTAG

Upstream 100 bases:

>100_bases
ATCCATAATCATATTTGCAAATGAATACTTGATGAGTCTCTGGCTGGTTGGGGTAACCCCCAACCACGCCTAATCGGAAC
CGGGGTGAAGGAGTTTCGTG

Downstream 100 bases:

>100_bases
GGCCTTACACGCGGCGGCTTCGCCGCAGAATCCCGATCTTCGCGGCTACCCATGTCTGGCACATCATGGGCGACCTTTTT
GCAACGCTAAAGCGAAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD

Sequences:

>Translated_347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD
>Mature_347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice

COG id: COG3704

COG function: function code U; Type IV secretory pathway, VirB6 components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbL/virB6 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VIRB6_BRUA2 (Q2YJ76)

Other databases:

- EMBL:   AF226278
- EMBL:   AM040265
- RefSeq:   YP_418308.1
- STRING:   Q2YJ76
- GeneID:   3827977
- GenomeReviews:   AM040265_GR
- KEGG:   bmf:BAB2_0063
- eggNOG:   COG3704
- HOGENOM:   HBG365988
- OMA:   YQSQVVT
- ProtClustDB:   CLSK884265
- BioCyc:   BMEL359391:BAB2_0063-MONOMER
- GO:   GO:0009405
- InterPro:   IPR007688

Pfam domain/function: PF04610 TrbL

EC number: NA

Molecular weight: Translated: 36134; Mature: 36134

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x235d6c5c)-; HASH(0x22b6c980)-; HASH(0x22fac204)-; HASH(0x234a0af8)-; HASH(0x23368958)-; HASH(0x22ce7170)-; HASH(0x235d0ef8)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGP
CCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHH
SLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIA
HCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
ILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHEEECCCCCCCHH
TSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH
>Mature Secondary Structure
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGP
CCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHH
SLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIA
HCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
ILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHEEECCCCCCCHH
TSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027