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The map label for this gene is infC [H]

Identifier: 16273648

GI number: 16273648

Start: 1395026

End: 1395568

Strand: Direct

Name: infC [H]

Synonym: HI1318m

Alternate gene names: 16273648

Gene position: 1395026-1395568 (Clockwise)

Preceding gene: 16273229

Following gene: 16273679

Centisome position: 76.23

GC content: 39.96

Gene sequence:

>543_bases
ATTAAAACCGTAAAAAAAGCACCGGCAGTAAATCGCCCAAACCGTATCAATGAAGAGATTCGTGTAAAAGAAGTTCGTTT
AATTGACCAAAATGGTGAACAAGCAGGGATTGTTTCTATTCAACAAGCCCTAGAAATGGCAGAGCAAGCAGAGCTTGATC
TTGTTGAAATTAGCCCAAATGCAGAGCCGCCGGTTTGTCGCATTATGAACTACGGTAAATTCCTTTACGAAAAAAGTAAA
ACCGCTAAAGAACAAAAGAAAAAACAAAAAGTTGTCCAAGTTAAGGAAATTAAATTCCGCCCAGGCACAGACGAAGGTGA
CTATCAAGTTAAATTACGTAGCTTAATCCGTTTCTTAGAAGACGGTGACAAAGCGAAAATTACCGTGCGTTTCCGCGGTC
GTGAAATGGCTCATCAAGACATCGGTTTAGATGTGTTAGAGCGCGTAAAAAATGATTTAGCTGAAATTTCAGTGGTTGAA
TCTGCACCAGGTAAATTAGAAGGCCGTCAGGCTGTAATGGTGTTAGCACCGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
AATTCGCGAGACTTTGCTCGTTCCTTGCGGGCAACAAATTTGAAATCTTTTATTTTTAGCGAAAAGATTTTTACTATTAA
CCAATAGAAGGAATACGATT

Downstream 100 bases:

>100_bases
GAATTTTGCTGAGATTTTTCAGCAAATCTTTTTGTTTAAGTTTGACTTAAATGAAAAGACAACTGCATGTTGGGCACACT
ACGCAGCCTAACTGCTTTTG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKTVKKAPAVNRPNRINEEIRVKEVRLIDQNGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKSK
TAKEQKKKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVE
SAPGKLEGRQAVMVLAPKKK

Sequences:

>Translated_180_residues
MKTVKKAPAVNRPNRINEEIRVKEVRLIDQNGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKSK
TAKEQKKKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVE
SAPGKLEGRQAVMVLAPKKK
>Mature_180_residues
MKTVKKAPAVNRPNRINEEIRVKEVRLIDQNGEQAGIVSIQQALEMAEQAELDLVEISPNAEPPVCRIMNYGKFLYEKSK
TAKEQKKKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLEDGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVE
SAPGKLEGRQAVMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=169, Percent_Identity=79.8816568047337, Blast_Score=251, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20423; Mature: 20423

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVKKAPAVNRPNRINEEIRVKEVRLIDQNGEQAGIVSIQQALEMAEQAELDLVEISPN
CCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCC
AEPPVCRIMNYGKFLYEKSKTAKEQKKKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
DGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVESAPGKLEGRQAVMVLAPKKK
CCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHEEHCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKTVKKAPAVNRPNRINEEIRVKEVRLIDQNGEQAGIVSIQQALEMAEQAELDLVEISPN
CCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCC
AEPPVCRIMNYGKFLYEKSKTAKEQKKKQKVVQVKEIKFRPGTDEGDYQVKLRSLIRFLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
DGDKAKITVRFRGREMAHQDIGLDVLERVKNDLAEISVVESAPGKLEGRQAVMVLAPKKK
CCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHEEHCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]