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The map label for this gene is moaC [H]

Identifier: 16273562

GI number: 16273562

Start: 1743650

End: 1744132

Strand: Reverse

Name: moaC [H]

Synonym: HI1675

Alternate gene names: 16273562

Gene position: 1744132-1743650 (Counterclockwise)

Preceding gene: 16273563

Following gene: 16273561

Centisome position: 95.3

GC content: 41.82

Gene sequence:

>483_bases
ATGACTACATTTACACATATCAATTCTCAAGGCGAAGCCAATATGGTGGATGTTTCTGCTAAAGCGGAAACTGTTCGTGA
AGCTCGTGCTGAAGCCATTGTAACTATGTCAAAAGAAACCCTTTCCATGATCGTGGAAGGTAAACATCACAAAGGCGATG
TATTTGCTACTGCTCGTATTGCGGGTATTCAAGCCGCAAAACGCACTTGGGAGCTTATCCCACTTTGCCATCCATTGTTA
CTTTCTAAAGTAGAAGTGAATTTAGAACCGTTACTCGAAACCAACCAAGTTCGCATTCAATCTCTTTGCAAATTAACTGG
AAAAACTGGCGTAGAAATGGAAGCACTAACTGCGGCAAGCGTAGCAGCCTTAACCATTTACGATATGTGTAAAGCCGTAC
AAAAAGACATAGTGATTGAGCACGTTCGCCTGTTAGAAAAGAGCGGTGGAAAATCAGGCCATTTTATTGCGGAGGAAAAA
TAA

Upstream 100 bases:

>100_bases
GGTGGCTAAAAAGCAAAGTGAGATGAATGGTAATATTCATCTGCTTCCTTTTGTCGCTTATTTAAAACATTCAATATTTT
AACCGCACTTTTATTATATT

Downstream 100 bases:

>100_bases
GATGTTAAATGTTTTATTTTTTGCTCAAACTCGTGAATTAATTGGCGTTGATGCCATTCAATTAGAAGATGATTTTGCCA
CTGCGGAAGCGGTGCGTGAA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLSMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVNLEPLLETNQVRIQSLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEHVRLLEKSGGKSGHFIAEEK

Sequences:

>Translated_160_residues
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLSMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVNLEPLLETNQVRIQSLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEHVRLLEKSGGKSGHFIAEEK
>Mature_159_residues
TTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLSMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLL
SKVEVNLEPLLETNQVRIQSLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEHVRLLEKSGGKSGHFIAEEK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=80.379746835443, Blast_Score=262, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI32566331, Length=157, Percent_Identity=40.7643312101911, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28574490, Length=151, Percent_Identity=56.953642384106, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=57.5342465753425, Blast_Score=148, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17468; Mature: 17336

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLSMIVEGKHHKGDVFATARI
CCCEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVNLEPLLETNQVRIQSLCKLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEHVRLLEKSGGKSGHFIAEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure 
TTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLSMIVEGKHHKGDVFATARI
CCEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVNLEPLLETNQVRIQSLCKLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEHVRLLEKSGGKSGHFIAEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA