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The map label for this gene is ilvH

Identifier: 16273478

GI number: 16273478

Start: 1651323

End: 1651814

Strand: Reverse

Name: ilvH

Synonym: HI1584

Alternate gene names: 16273478

Gene position: 1651814-1651323 (Counterclockwise)

Preceding gene: 16273479

Following gene: 16273476

Centisome position: 90.26

GC content: 36.79

Gene sequence:

>492_bases
ATGCGTAGAATTTTATCTGTTTTACTCGAAAATGAATCGGGAGCATTGTCGCGTGTTGTTGGTTTATTCTCTCAACGTGC
CTTTAATATTGAAAGTTTGACGGTTGCACCAACGGATGATCCAACGCTTTCTCGAATGACCATTGAAGCTGTGGGCGATG
CTCAGGCATTGGAGCAAATCGAAAAACAACTTCATAAATTAGTGGATGTGTTTAAAGTGGTTAATTTAAGTGAGCAGGAA
CATATAGAACGAGAAATTGTTTTAGCGAAAGTAAGAGCAGTAGGTTCATCTCGCGATGAAATTAAACGATTAGCAGATAT
TTTCCGCGGTCAAATTGTAGATGTAACACCAAAGTCTTACACAATTCAATTAAGCGGTACAAATGATAAAGTTGATGCGT
TTATTTCTGCATTGAAAGAAGAAACTACATTGTTAGAAATTGTTCGTTCTGGATTGATTAGTGTGTCTCGTGGAGAAAAG
AATATTCTTTAA

Upstream 100 bases:

>100_bases
ATATTAATGTAGATGAATCTGAACACGTTTATCCAATGCAAATTCGTGGTGGTGCAATGAATGAAATGATTTTAAGTAAA
CCTCAAGAGGAGACAAACTA

Downstream 100 bases:

>100_bases
AGTAGGGGCGTAAAGTGCGGAAATATTTTAATAGAATTTTACCGCACTTTATTAGAAATATATTTGTTTTTAGTTTTTTT
ATAAAAAAATCGTGACCAAG

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQIEKQLHKLVDVFKVVNLSEQE
HIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSYTIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEK
NIL

Sequences:

>Translated_163_residues
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQIEKQLHKLVDVFKVVNLSEQE
HIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSYTIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEK
NIL
>Mature_163_residues
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQIEKQLHKLVDVFKVVNLSEQE
HIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSYTIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEK
NIL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=160, Percent_Identity=66.25, Blast_Score=229, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=28.2926829268293, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_HAEIN (P45260)

Other databases:

- EMBL:   L42023
- PIR:   B64131
- RefSeq:   NP_439729.1
- ProteinModelPortal:   P45260
- SMR:   P45260
- GeneID:   950447
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1584
- TIGR:   HI_1584
- HOGENOM:   HBG335310
- OMA:   IERELAM
- ProtClustDB:   PRK11895
- BioCyc:   HINF71421:HI_1584-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 18087; Mature: 18087

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQI
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHH
EKQLHKLVDVFKVVNLSEQEHIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCEE
TIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEKNIL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQI
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHH
EKQLHKLVDVFKVVNLSEQEHIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCEE
TIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEKNIL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800