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The map label for this gene is bioC

Identifier: 16273451

GI number: 16273451

Start: 1621835

End: 1622617

Strand: Reverse

Name: bioC

Synonym: HI1551

Alternate gene names: 16273451

Gene position: 1622617-1621835 (Counterclockwise)

Preceding gene: 16273452

Following gene: 16273450

Centisome position: 88.66

GC content: 40.74

Gene sequence:

>783_bases
ATGGGATCATTAACTTCCGTAGATAAATCGCGCATTCGGCAGGCTTTCCAAAAAGCATTAAACGATTATGACAGGCACGC
CTTAATCCAACAGAAAATGACGATTAATTTAATGGCGCATTTGCAAGACTATTTACCAAATGGGTCACTAGATAGTGTTT
TGGAGCTTGGTTGCGGGTCTGGTATGTTGAGTTCATTGTTGCAAAAACAGATTTCAGCGGATTATTGGTTATTTAATGAT
TTGTGCGATGTGCAGACCCAACTGGCTGAAAAATTGCCGCAATCCTTTGATTTTTATTGCGGCGATGCCGAACATTTCCT
TTTTTTGCAACAATTTGACTTAATCGCAAGCGCATCCGCCGTGCAATGGTTTCACCAACCCGACGCTTTTATCGCCCATT
GCAAAACAGGCTTGAAAACAAACGGATTATTGGCGGTTGCAACCTTTGGCGAAGACAATTTAAAAGAAGTCCGCCAGATC
ACAAATATAGGCTTAAATTACCCGACTTTATCCCAATGGCAGACTTGGTTAGCCAAAGATTTTGAGCTTTTATGGTGTGA
GGATTTTAAGGTAATACTAGACTTTGATACGCCGTTAGATGTACTCAAACACCTTAAATATACAGGCGTAACAGCCACGA
ACCAAAAAAATTGGACAAGAAAAAATCTCAATGGATTTATTGGCGATTACTTGTCGGCGTTTGGTATGCCGTCGGGCAAA
GTGCGCCTGACTTATCATCCGTTATTTTTTATCGCACGCTATTCTCACATAGAAAATCAGTAA

Upstream 100 bases:

>100_bases
CGCCAGCTAATCAGCACCAATATTGGGCATTGCGTTGTGCAGTTCAGGAAATAGAGGGTGAGCATTATGTGTTTTCAAGA
TTTACCCACTGGTCGGCATT

Downstream 100 bases:

>100_bases
GGAATATTTATGGGAAAGGTTATTTTTATATCTGGCATTGATACTGATGTGGGAAAAACGATTGCAACAGGCATTTATGC
TAAAAAGTTGATGGAACAAG

Product: biotin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGSLTSVDKSRIRQAFQKALNDYDRHALIQQKMTINLMAHLQDYLPNGSLDSVLELGCGSGMLSSLLQKQISADYWLFND
LCDVQTQLAEKLPQSFDFYCGDAEHFLFLQQFDLIASASAVQWFHQPDAFIAHCKTGLKTNGLLAVATFGEDNLKEVRQI
TNIGLNYPTLSQWQTWLAKDFELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNWTRKNLNGFIGDYLSAFGMPSGK
VRLTYHPLFFIARYSHIENQ

Sequences:

>Translated_260_residues
MGSLTSVDKSRIRQAFQKALNDYDRHALIQQKMTINLMAHLQDYLPNGSLDSVLELGCGSGMLSSLLQKQISADYWLFND
LCDVQTQLAEKLPQSFDFYCGDAEHFLFLQQFDLIASASAVQWFHQPDAFIAHCKTGLKTNGLLAVATFGEDNLKEVRQI
TNIGLNYPTLSQWQTWLAKDFELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNWTRKNLNGFIGDYLSAFGMPSGK
VRLTYHPLFFIARYSHIENQ
>Mature_259_residues
GSLTSVDKSRIRQAFQKALNDYDRHALIQQKMTINLMAHLQDYLPNGSLDSVLELGCGSGMLSSLLQKQISADYWLFNDL
CDVQTQLAEKLPQSFDFYCGDAEHFLFLQQFDLIASASAVQWFHQPDAFIAHCKTGLKTNGLLAVATFGEDNLKEVRQIT
NIGLNYPTLSQWQTWLAKDFELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNWTRKNLNGFIGDYLSAFGMPSGKV
RLTYHPLFFIARYSHIENQ

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOC_HAEIN (P45249)

Other databases:

- EMBL:   L42023
- PIR:   C64129
- RefSeq:   NP_439700.1
- ProteinModelPortal:   P45249
- GeneID:   950415
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1551
- NMPDR:   fig|71421.1.peg.1478
- TIGR:   HI_1551
- HOGENOM:   HBG296726
- OMA:   TWLAKDF
- ProtClustDB:   CLSK870661
- BioCyc:   HINF71421:HI_1551-MONOMER
- InterPro:   IPR011814
- InterPro:   IPR013216
- TIGRFAMs:   TIGR02072

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 29676; Mature: 29545

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSLTSVDKSRIRQAFQKALNDYDRHALIQQKMTINLMAHLQDYLPNGSLDSVLELGCGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
GMLSSLLQKQISADYWLFNDLCDVQTQLAEKLPQSFDFYCGDAEHFLFLQQFDLIASASA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHH
VQWFHQPDAFIAHCKTGLKTNGLLAVATFGEDNLKEVRQITNIGLNYPTLSQWQTWLAKD
HHHHCCCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
FELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNWTRKNLNGFIGDYLSAFGMPSGK
CEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
VRLTYHPLFFIARYSHIENQ
EEEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800