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The map label for this gene is aroG

Identifier: 16273447

GI number: 16273447

Start: 1617864

End: 1618952

Strand: Reverse

Name: aroG

Synonym: HI1547

Alternate gene names: 16273447

Gene position: 1618952-1617864 (Counterclockwise)

Preceding gene: 16273448

Following gene: 16273445

Centisome position: 88.46

GC content: 39.03

Gene sequence:

>1089_bases
ATGGCTAAAGAGAAAATTGAAATTGTCGTGGCAAACGACGATACGCGAATTGAAAAAGTCGATCAGGTGTTACCACCCAT
TGCCTTATTAGAAAAATACCCAGCAAGTGAACAGGCTGCGGCGTTAGTGAAGCAAACTCGTCATGAGGCACATAATATTA
TTCATGGTAAAGATGATCGTTTATTAGTCGTGATTGGGCCTTGCTCTATTCATGATCCGAAAGCAGCCATTGAATATGCG
ACTCGTTTAAAACCATTACGTGAAAAATACAAAGATAGCCTTGAAATTATTATGCGTGTGTATTTTGAGAAACCGCGTAC
AACGGTGGGTTGGAAAGGTTTAATTAATGAACCATATTTGAATGATACTTATCGTTTAAATGATGGGTTACGTATTGCAC
GGAAATTACTTTCAGATATTAATGATCTTGGTGTGCCTGCAGCGGGCGAGTTTTTAGATATGATTACACCTCAGTATTTG
GCAGATTTTATGAGCTGGGGGGCGATTGGGGCTAGAACAACAGAATCACAAGTTCATCGTGAGTTGGCTTCAGGTTTATC
TTGTGCTGTTGGGTTTAAAAATGCCACTAATGGTGGTGTGAAAGTCGCTTTAGATGCAATTGGTGCAGCGGAAGCTCCTC
ACTATTTCTTATCTGTCACTAAATTTGGTCATTCTGCAATTGTTTCTACAAAAGGGAATGAAGATTGCCATATTATTTTA
CGAGGTGGAGATAAAGGCCCTAACTATAGTGCTGAAGATGTAGAAAAAGTTTGTGCTGATATTGAAAAAACAGGGCGTAT
TCCACACGTTATGGTTGATTTTAGCCATGCAAACAGCAGTAAACAATATAAAAAGCAAATGGATGTTTGCCAAGACGTAT
GTAATCAGATTGCATTTGGTTCTAAACAAATCTTTGGCGTAATGGTGGAAAGCCATTTAGTGGAAGGTCGTCAAGATTTA
GTTGATGGCAAAGCACAGACTTATGGACAAAGTATTACGGATGCGTGCATTGGATGGGAAGATTCTGAAAGATTATTGCA
ACAACTTTCTGATGCAGTTATTGCTAGACGTAAAGCGACGAGTAATTAA

Upstream 100 bases:

>100_bases
TTATTCTAAAAAAACATATCGAACTAGTTTACTAGTACAAAAATAAGTGTAGATTAGCTACATAATTTAAACACAACATT
TGAAAGCAAGAGAGTAATGT

Downstream 100 bases:

>100_bases
TTGAAATATAATCTAGATACTAGATAGAAGTGCGGTTGATTTTCACCGCACTTTTTTATTTGCTTTTAACTACGCTGCCC
ATTTCATTTTATCGCGACGT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDRLLVVIGPCSIHDPKAAIEYA
TRLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYLNDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYL
ADFMSWGAIGARTTESQVHRELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
RGGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFGSKQIFGVMVESHLVEGRQDL
VDGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKATSN

Sequences:

>Translated_362_residues
MAKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDRLLVVIGPCSIHDPKAAIEYA
TRLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYLNDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYL
ADFMSWGAIGARTTESQVHRELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
RGGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFGSKQIFGVMVESHLVEGRQDL
VDGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKATSN
>Mature_361_residues
AKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDRLLVVIGPCSIHDPKAAIEYAT
RLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYLNDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYLA
DFMSWGAIGARTTESQVHRELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIILR
GGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFGSKQIFGVMVESHLVEGRQDLV
DGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKATSN

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family

Homologues:

Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=71.9653179190751, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=54.4927536231884, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788953, Length=328, Percent_Identity=50, Blast_Score=340, Evalue=8e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=53.1428571428571, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=50, Blast_Score=353, Evalue=2e-98,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROG_HAEIN (P44303)

Other databases:

- EMBL:   L42023
- PIR:   I64128
- RefSeq:   NP_439696.1
- ProteinModelPortal:   P44303
- SMR:   P44303
- GeneID:   950411
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1547
- NMPDR:   fig|71421.1.peg.1474
- TIGR:   HI_1547
- HOGENOM:   HBG670536
- OMA:   MDNSFKL
- ProtClustDB:   PRK09261
- BioCyc:   HINF71421:HI_1547-MONOMER
- BRENDA:   2.5.1.54
- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR21225
- PIRSF:   PIRSF001361
- TIGRFAMs:   TIGR00034

Pfam domain/function: PF00793 DAHP_synth_1

EC number: =2.5.1.54

Molecular weight: Translated: 39937; Mature: 39806

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDR
CCCCEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LLVVIGPCSIHDPKAAIEYATRLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYLADFMSWGAIGARTTESQVHR
CCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHH
ELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
HHHCCCEEEECCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEE
RGGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFG
ECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
SKQIFGVMVESHLVEGRQDLVDGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKAT
CHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
SN
CC
>Mature Secondary Structure 
AKEKIEIVVANDDTRIEKVDQVLPPIALLEKYPASEQAAALVKQTRHEAHNIIHGKDDR
CCCEEEEEEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LLVVIGPCSIHDPKAAIEYATRLKPLREKYKDSLEIIMRVYFEKPRTTVGWKGLINEPYL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NDTYRLNDGLRIARKLLSDINDLGVPAAGEFLDMITPQYLADFMSWGAIGARTTESQVHR
CCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHH
ELASGLSCAVGFKNATNGGVKVALDAIGAAEAPHYFLSVTKFGHSAIVSTKGNEDCHIIL
HHHCCCEEEECCCCCCCCCEEEEEEHHCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEE
RGGDKGPNYSAEDVEKVCADIEKTGRIPHVMVDFSHANSSKQYKKQMDVCQDVCNQIAFG
ECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
SKQIFGVMVESHLVEGRQDLVDGKAQTYGQSITDACIGWEDSERLLQQLSDAVIARRKAT
CHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
SN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800