Click here to switch to the map view.

The map label for this gene is kicA

Identifier: 16273284

GI number: 16273284

Start: 1465106

End: 1465837

Strand: Direct

Name: kicA

Synonym: HI1373

Alternate gene names: 16273284

Gene position: 1465106-1465837 (Clockwise)

Preceding gene: 30995445

Following gene: 16273285

Centisome position: 80.05

GC content: 40.16

Gene sequence:

>732_bases
ATGACAGATATTCAAGATGTAATTTCCCCAAAACTCGCTGTGGCGATTGCAAATCCAATATTTCCAGCGGTGGATAGTTT
ATTGCGCTCGGGTCGCCATATCAGCACGGAACATTTAGATAATCACGCATTTTTAATGGATTTCCAAAATGAATTGGACG
GTTTTTATCGTCGCTATAACGTGGAACTAATTCGTGCGCCAGAAGGATTCTTCTATCTTCGCCCGAAAGCAACGACATTA
ATTGCGCGTTCAGTACTTTCTGAGTTGGAAATGCTTGTTGGTAAAGTGCTTTGTTATCTTTATTTAAGCCCAGAACGTTT
AGCCCAACAGGGCATTTTTAGTACGCAAGAAGTGTATGATGAATTATTAAATCTTGCCGATGAAGGAAAATTATTAAAAG
CAGTTAATCAGCGTTCAAGTGGTTCTGACTTAGATAAACAAAAATTGGCAGAAAAAGTGCGGGCTGCAATTGGTCGTTTA
CGTCGTCTAGGTATGATTCAAACTGTTGGTGAACAAAATAGTGGGAAATTTACGATTTCTGAATCTGTATTTCGTTTTGG
TGCGGAAGTACGTAGCGGAGATGATCCATTAGAGTCCCAAGCTAGACTCATTCGTGATGGGGAAGCCGCAACACCTGATT
CCTTAGCGTTGGAAAAACAAGCGCAATTAATGGAAAACGATACGAAAAGTGCGGATGAAATTGACGAAGAATTTGACGGA
GAACAAGAATAA

Upstream 100 bases:

>100_bases
GCAATTAATAAACGTGGCGCAGAAGTGCAAGCGCATGTGATTGATAAGTATTGATTTCGTGGCTTATTAAAAAACGAATT
TATAAAATGAGAAATTAACC

Downstream 100 bases:

>100_bases
TGTCTGATGTTTTTGAATTAGAAAATGAAATCGAATTAGAGAGCGATGAAGTCATTCTGGAAAATGAAAACGTCGAAGAA
ATCGTTGATGCACCTATACC

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTDIQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATTL
IARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRL
RRLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLESQARLIRDGEAATPDSLALEKQAQLMENDTKSADEIDEEFDG
EQE

Sequences:

>Translated_243_residues
MTDIQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATTL
IARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRL
RRLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLESQARLIRDGEAATPDSLALEKQAQLMENDTKSADEIDEEFDG
EQE
>Mature_242_residues
TDIQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYNVELIRAPEGFFYLRPKATTLI
ARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYDELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRLR
RLGMIQTVGEQNSGKFTISESVFRFGAEVRSGDDPLESQARLIRDGEAATPDSLALEKQAQLMENDTKSADEIDEEFDGE
QE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family

Homologues:

Organism=Escherichia coli, GI226510932, Length=242, Percent_Identity=65.702479338843, Blast_Score=315, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKE_HAEIN (P45186)

Other databases:

- EMBL:   L42023
- PIR:   C64120
- RefSeq:   NP_439525.1
- GeneID:   950288
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1373
- NMPDR:   fig|71421.1.peg.1310
- TIGR:   HI_1373
- HOGENOM:   HBG296837
- OMA:   GKVLCYL
- ProtClustDB:   PRK05256
- BioCyc:   HINF71421:HI_1373-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01802
- InterPro:   IPR007385

Pfam domain/function: PF04288 MukE

EC number: NA

Molecular weight: Translated: 27229; Mature: 27098

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYN
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHC
VELIRAPEGFFYLRPKATTLIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYD
EEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
ELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRLRRLGMIQTVGEQNSGKFTIS
HHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ESVFRFGAEVRSGDDPLESQARLIRDGEAATPDSLALEKQAQLMENDTKSADEIDEEFDG
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
EQE
CCC
>Mature Secondary Structure 
TDIQDVISPKLAVAIANPIFPAVDSLLRSGRHISTEHLDNHAFLMDFQNELDGFYRRYN
CCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHC
VELIRAPEGFFYLRPKATTLIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFSTQEVYD
EEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
ELLNLADEGKLLKAVNQRSSGSDLDKQKLAEKVRAAIGRLRRLGMIQTVGEQNSGKFTIS
HHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHH
ESVFRFGAEVRSGDDPLESQARLIRDGEAATPDSLALEKQAQLMENDTKSADEIDEEFDG
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCC
EQE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800