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The map label for this gene is tmcA [H]

Identifier: 16273173

GI number: 16273173

Start: 1329939

End: 1331000

Strand: Direct

Name: tmcA [H]

Synonym: HI1254

Alternate gene names: 16273173

Gene position: 1329939-1331000 (Clockwise)

Preceding gene: 16273172

Following gene: 16273174

Centisome position: 72.67

GC content: 39.74

Gene sequence:

>1062_bases
ATGCCATCTCGCCAGCTTCAAATTTTAATCAGAAAAACTTTGCCGCTTGTGCCTGATCACGTATTAATTATCGGCGAAAG
TGGCATTGCTTTTTCTAAAGCAACGAATTTGCTCGGGCAAGAATTTGAACATATTTTATTTGATGGACGAAATGGCATTC
ATCTTGAAGCACTGGCTATTGCAGCTGGAACACTGAAAATGGGCGGCACACTTTGTTTAGTGTTATCTGATTGGGAAAAT
TTATCTCAGCAGCCTGATCAAGATAGTTTACGTTGGAATGGAAATCAGTCAGCTATCGCCACGCCTAATTTTATTTATCA
TTTCAAACAGTGCATTGAACGTTATCATTTCCCCATTTTAAGAGAGGAAAGTGCGGTTGAATTTCCTACGGTTTTTTATT
CTAACGAACATCACAAAAATGCTACGTTAGCGCAACAACAAATTATCGAGAATATTTTACAGGCCGAGCAGGATATTTAT
TTTCTAACCGCCAAGCGGGGAAGAGGAAAATCCGCATTATTGGGTATGCTTGCTAACCAAATTCAAGCACCAGTTTATCT
CACCGCACCGAATAAAAGTGCGGTGCATTCCGTTATTGAATTTTCAGAAGGGGACATTGAATTTATTGCGCCAGATGAAT
TGGCTTTGACGTTACAAACTGAACCCGAATTTAGTCAATCTGCTTGGTTGCTGGTAGATGAAGCGGCGATGATCCCATTG
CCGTTATTGCAAGAATATTCTCGATATTTTCAACATATTGTCTTTAGTACTACAATTCATAGCTACGAAGGTACGGGGCG
TGGTTTCGAATTAAAATTTAAACGGAAAATTCACCGCACTTTTCAGCATTTTGAGCTTAAACAGCCTCTACGTTGGCAAG
AAAATGATCCGTTAGAACATTTTATTGATGATCTTTTATTGCTAAATGCCGAAGATGATTTTCAGCACTTTGACTATAGC
AATATTACTTATAACATAGAGGAAAACGCTAAAAATCTTTCCTTCCCCTGCTTGCGGGGGAAGGTGCCCGAAGGGCCGAA
GGGGGGATTTAGATATAGCTAG

Upstream 100 bases:

>100_bases
TTTTTCAGTAAAAAAGTTTCTCAACCCAAAAGCATTTTCTTTTGGCTTGCTTGCGTAAGTTTTATTGGTGCGATGTTAAT
TGCCTATTTAAAATAAAACG

Downstream 100 bases:

>100_bases
CCTCCCTCAAGCTTTGGAGGCTCTCCTCACAAGTAAGGGGAGTGAAGGAAAATATAATCGTCAATTTTTCTTTCGAGATT
TTTATGGGCTAATGACGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPSRQLQILIRKTLPLVPDHVLIIGESGIAFSKATNLLGQEFEHILFDGRNGIHLEALAIAAGTLKMGGTLCLVLSDWEN
LSQQPDQDSLRWNGNQSAIATPNFIYHFKQCIERYHFPILREESAVEFPTVFYSNEHHKNATLAQQQIIENILQAEQDIY
FLTAKRGRGKSALLGMLANQIQAPVYLTAPNKSAVHSVIEFSEGDIEFIAPDELALTLQTEPEFSQSAWLLVDEAAMIPL
PLLQEYSRYFQHIVFSTTIHSYEGTGRGFELKFKRKIHRTFQHFELKQPLRWQENDPLEHFIDDLLLLNAEDDFQHFDYS
NITYNIEENAKNLSFPCLRGKVPEGPKGGFRYS

Sequences:

>Translated_353_residues
MPSRQLQILIRKTLPLVPDHVLIIGESGIAFSKATNLLGQEFEHILFDGRNGIHLEALAIAAGTLKMGGTLCLVLSDWEN
LSQQPDQDSLRWNGNQSAIATPNFIYHFKQCIERYHFPILREESAVEFPTVFYSNEHHKNATLAQQQIIENILQAEQDIY
FLTAKRGRGKSALLGMLANQIQAPVYLTAPNKSAVHSVIEFSEGDIEFIAPDELALTLQTEPEFSQSAWLLVDEAAMIPL
PLLQEYSRYFQHIVFSTTIHSYEGTGRGFELKFKRKIHRTFQHFELKQPLRWQENDPLEHFIDDLLLLNAEDDFQHFDYS
NITYNIEENAKNLSFPCLRGKVPEGPKGGFRYS
>Mature_352_residues
PSRQLQILIRKTLPLVPDHVLIIGESGIAFSKATNLLGQEFEHILFDGRNGIHLEALAIAAGTLKMGGTLCLVLSDWENL
SQQPDQDSLRWNGNQSAIATPNFIYHFKQCIERYHFPILREESAVEFPTVFYSNEHHKNATLAQQQIIENILQAEQDIYF
LTAKRGRGKSALLGMLANQIQAPVYLTAPNKSAVHSVIEFSEGDIEFIAPDELALTLQTEPEFSQSAWLLVDEAAMIPLP
LLQEYSRYFQHIVFSTTIHSYEGTGRGFELKFKRKIHRTFQHFELKQPLRWQENDPLEHFIDDLLLLNAEDDFQHFDYSN
ITYNIEENAKNLSFPCLRGKVPEGPKGGFRYS

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=312, Percent_Identity=37.5, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 40331; Mature: 40200

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRQLQILIRKTLPLVPDHVLIIGESGIAFSKATNLLGQEFEHILFDGRNGIHLEALAI
CCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
AAGTLKMGGTLCLVLSDWENLSQQPDQDSLRWNGNQSAIATPNFIYHFKQCIERYHFPIL
EHHHEECCCEEEEEEECCHHHCCCCCCCCCEECCCCCCEECCHHHHHHHHHHHHHCCCEE
REESAVEFPTVFYSNEHHKNATLAQQQIIENILQAEQDIYFLTAKRGRGKSALLGMLANQ
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
IQAPVYLTAPNKSAVHSVIEFSEGDIEFIAPDELALTLQTEPEFSQSAWLLVDEAAMIPL
HCCCEEEECCCHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCH
PLLQEYSRYFQHIVFSTTIHSYEGTGRGFELKFKRKIHRTFQHFELKQPLRWQENDPLEH
HHHHHHHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FIDDLLLLNAEDDFQHFDYSNITYNIEENAKNLSFPCLRGKVPEGPKGGFRYS
HHHHHEEECCCCCHHHCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSRQLQILIRKTLPLVPDHVLIIGESGIAFSKATNLLGQEFEHILFDGRNGIHLEALAI
CCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
AAGTLKMGGTLCLVLSDWENLSQQPDQDSLRWNGNQSAIATPNFIYHFKQCIERYHFPIL
EHHHEECCCEEEEEEECCHHHCCCCCCCCCEECCCCCCEECCHHHHHHHHHHHHHCCCEE
REESAVEFPTVFYSNEHHKNATLAQQQIIENILQAEQDIYFLTAKRGRGKSALLGMLANQ
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
IQAPVYLTAPNKSAVHSVIEFSEGDIEFIAPDELALTLQTEPEFSQSAWLLVDEAAMIPL
HCCCEEEECCCHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCH
PLLQEYSRYFQHIVFSTTIHSYEGTGRGFELKFKRKIHRTFQHFELKQPLRWQENDPLEH
HHHHHHHHHHHHHHHHHEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FIDDLLLLNAEDDFQHFDYSNITYNIEENAKNLSFPCLRGKVPEGPKGGFRYS
HHHHHEEECCCCCHHHCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]