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The map label for this gene is trpG [C]

Identifier: 16273095

GI number: 16273095

Start: 1241359

End: 1241940

Strand: Direct

Name: trpG [C]

Synonym: HI1171

Alternate gene names: 16273095

Gene position: 1241359-1241940 (Clockwise)

Preceding gene: 16273092

Following gene: 16273096

Centisome position: 67.83

GC content: 35.4

Gene sequence:

>582_bases
ATGAAATTACTCATCATTAATAATCACGATTCTTTTACTTTTAACTTGGTGGATTTAATTCGAAAATTAAATGTGCCTTA
TGATGTTTTAAACGTAGAAGATTTGAAAGAAAATACAGCGGAAAATTATAGCCATATATTGATTTCGCCAGGGCCTGATA
TACCACGCGCTTATCCACAACTTTTTTCCATGTTGGAAAAATATTATCAGCAAAAATCTATTTTAGGTGTGTGTTTAGGG
CATCAAACCTTATGTGAATTTTTTGGTGGTACATTGTATAACTTAGAGAATGTTCGTCACGGGCAGAAACGAACATTAAA
AGTGCGGTCAAATTCTCCATTGTTTTTTGATCTTCCAACTGAATTTAATATCGGGCTATATCATTCTTGGGGCGTACAGG
AAGAAGATTTTCCTGATTGCCTAGAAATCACCGCACTTTGTGATGAAGATGTAGTGATGGCGATGCAACATAAATCTTTG
CCAATTTATAGTGTCCAGTTTCATCCAGAATCTTATATGTCAGACTTTGGCGAGAAAATTTTGCGTAATTGGTTGGCGAT
TCCTCCCACAACTAACCCATAA

Upstream 100 bases:

>100_bases
CGTTGTTTGCCATAATGATTAGCCTGTTCAATAAAATGTTGCATTGTGCTTTGTGCCATTTTGCGTAAAATGACCTGATT
ATAACGAATACCGAACTGTT

Downstream 100 bases:

>100_bases
TACCGCTTGCTTATTAAGCAAAAATGCGTATTATAGCCGTCTATACGTCAATACATCCAAATTTAAAAGAAGAAGAGAGA
AAATATGTCTAGTTATTTAT

Product: putative anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKLLIINNHDSFTFNLVDLIRKLNVPYDVLNVEDLKENTAENYSHILISPGPDIPRAYPQLFSMLEKYYQQKSILGVCLG
HQTLCEFFGGTLYNLENVRHGQKRTLKVRSNSPLFFDLPTEFNIGLYHSWGVQEEDFPDCLEITALCDEDVVMAMQHKSL
PIYSVQFHPESYMSDFGEKILRNWLAIPPTTNP

Sequences:

>Translated_193_residues
MKLLIINNHDSFTFNLVDLIRKLNVPYDVLNVEDLKENTAENYSHILISPGPDIPRAYPQLFSMLEKYYQQKSILGVCLG
HQTLCEFFGGTLYNLENVRHGQKRTLKVRSNSPLFFDLPTEFNIGLYHSWGVQEEDFPDCLEITALCDEDVVMAMQHKSL
PIYSVQFHPESYMSDFGEKILRNWLAIPPTTNP
>Mature_193_residues
MKLLIINNHDSFTFNLVDLIRKLNVPYDVLNVEDLKENTAENYSHILISPGPDIPRAYPQLFSMLEKYYQQKSILGVCLG
HQTLCEFFGGTLYNLENVRHGQKRTLKVRSNSPLFFDLPTEFNIGLYHSWGVQEEDFPDCLEITALCDEDVVMAMQHKSL
PIYSVQFHPESYMSDFGEKILRNWLAIPPTTNP

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI1789760, Length=191, Percent_Identity=31.9371727748691, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=29.1005291005291, Blast_Score=87, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=29.1666666666667, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=26.8867924528302, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281365319, Length=191, Percent_Identity=28.7958115183246, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1171_HAEIN (P44339)

Other databases:

- EMBL:   L42023
- PIR:   G64187
- RefSeq:   NP_439329.1
- ProteinModelPortal:   P44339
- SMR:   P44339
- GeneID:   950129
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1171
- NMPDR:   fig|71421.1.peg.1122
- TIGR:   HI_1171
- HOGENOM:   HBG292341
- OMA:   IGLYHSW
- ProtClustDB:   PRK06895
- BioCyc:   HINF71421:HI_1171-MONOMER
- BRENDA:   4.1.3.27
- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221
- PRINTS:   PR00097
- PRINTS:   PR00096
- TIGRFAMs:   TIGR00566

Pfam domain/function: PF00117 GATase

EC number: =4.1.3.27

Molecular weight: Translated: 22301; Mature: 22301

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 78-78 ACT_SITE 168-168 ACT_SITE 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLIINNHDSFTFNLVDLIRKLNVPYDVLNVEDLKENTAENYSHILISPGPDIPRAYPQ
CEEEEEECCCCEEEHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHH
LFSMLEKYYQQKSILGVCLGHQTLCEFFGGTLYNLENVRHGQKRTLKVRSNSPLFFDLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCEEEEEECCCCEEEECCC
EFNIGLYHSWGVQEEDFPDCLEITALCDEDVVMAMQHKSLPIYSVQFHPESYMSDFGEKI
CCCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHH
LRNWLAIPPTTNP
HHHCCCCCCCCCC
>Mature Secondary Structure
MKLLIINNHDSFTFNLVDLIRKLNVPYDVLNVEDLKENTAENYSHILISPGPDIPRAYPQ
CEEEEEECCCCEEEHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHH
LFSMLEKYYQQKSILGVCLGHQTLCEFFGGTLYNLENVRHGQKRTLKVRSNSPLFFDLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCEEEEEECCCCEEEECCC
EFNIGLYHSWGVQEEDFPDCLEITALCDEDVVMAMQHKSLPIYSVQFHPESYMSDFGEKI
CCCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHH
LRNWLAIPPTTNP
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800