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The map label for this gene is pmbA

Identifier: 16273077

GI number: 16273077

Start: 1219461

End: 1220816

Strand: Direct

Name: pmbA

Synonym: HI1152

Alternate gene names: 16273077

Gene position: 1219461-1220816 (Clockwise)

Preceding gene: 16273071

Following gene: 16273078

Centisome position: 66.63

GC content: 40.41

Gene sequence:

>1356_bases
ATGAAACCAGCTGAAAATTCAACCGCACTTTTAAAAGCACAAGAACAAGAATTACGTCAAGCCGTCAGTTTTGCAGTGGA
GTTAGCAACGAAAGCTGGCGCAAGTGCAGAAGTCGCGGTCACAAAAGTGAGCGGTTTATCCGTATCTGCTCGTTTGCAAG
AAATTGAAAACGTAGAATTTACTAATGATGGCGCATTGGGGATCTCCGTTTATATGGGGCAACAAAAAGGCAATGCTTCT
ACTTCCGATCTAAGCGAAAGCGCAATTAAAAATGCGGTAGAAGCCGCACTTGCAATTGCAAAATACACTTCACCCGATGA
TTGCACAGGGTTGGCTGATAAAGATCTAATGGCTTTTGATGCGCCTGATTTAGAACTTTATCATGCTGCTGATATAGATG
TTGATAAAGCGACGGAATTGGCACTTCAAGCAGAACAAGCCGCTTTGCAAGCGGATGAACGCATTATAAATAGTAATGGT
GCAAGTTTTAATTCACATACAGGCGTGAAAGTTTATGGAAATAGCCATGGCATGTTGCAAAGTTATTTATCAAGCCGTTA
TTCCTTATCTTGTTCGGTTATTGGTGGCGTAGAAGATGCCTTAGAAAATGATTACGAATACACGATCTCTCGTGAATTCG
ATAAACTCCAATCGCCAATTTGGGTTGGCGAAAATTGTGCAAAGAAAGTCGTTTCTCGTTTAAATCCTCAAAAATTGAGT
ACACGAGAAGTGCCTGTCATTTTCTTAAATGATGTTGCAACTGGTATTATTTCTCATTTTGCCGCTGCAATAAGTGGTGG
CAGCTTATATAGAAAATCAAGTTTCTTACTCGATCATTTAGGTAAACAGGTCTTACCAGATTGGTTTAGCATCAGTGAGA
GACCACATTTATTACGTCGTTTGGCTTCTACGCCTTTTGATAGTGAAGGTGTTCGCACGCAAGATCGTGAAATTGTCGAA
AACGGCATATTACAAACTTATTTAGTGACAAGTTACAGTGGTAAAAAACTTGGTATGTCAAGTACAGGTCATGCTGGAGG
CATTCACAACTGGCTTGTTAAGCCAAATTTAACGGGTGGATTGACCGCACTTTTACGTCAAATGGGAACAGGCTTACTCG
TAACAGATGTTATGGGGCAAGGTGTCAATATTGTTACTGGCGATTATTCCCGTGGCGCATCAGGTTTTTGGGTGGAAAAT
GGGGAAATTCAATATCCCGTCGCCGAAATTACTATTGCGGGACAATTGCAAGATATGTTGAAGAATATGCTTGCTGTAGC
GGATGATATAGAGCATCGTTCTAACATCCAAACGGGTTCTATTTTGTTAGATAAAATGAAAATTTCAGGAAATTAA

Upstream 100 bases:

>100_bases
ACGTTTTGCCATTTTTTATCCTTTATAAAAATTGGCGTGCATTTTACCATAAACTTTAAAAATAAGATAAAATGTTGAAA
ATTTTTAATAGGAAAAAATA

Downstream 100 bases:

>100_bases
GAATATTTTTGAAATTGAGAATAATTCTTATTGACAATGAATGAATATCTGTTACTATACGCACATCTGTTAAGCGATTG
CAGGTTGCTCCAACAGGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEFTNDGALGISVYMGQQKGNAS
TSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNG
ASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLS
TREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVE
NGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVEN
GEIQYPVAEITIAGQLQDMLKNMLAVADDIEHRSNIQTGSILLDKMKISGN

Sequences:

>Translated_451_residues
MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEFTNDGALGISVYMGQQKGNAS
TSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNG
ASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLS
TREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVE
NGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVEN
GEIQYPVAEITIAGQLQDMLKNMLAVADDIEHRSNIQTGSILLDKMKISGN
>Mature_451_residues
MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEFTNDGALGISVYMGQQKGNAS
TSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNG
ASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLS
TREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVE
NGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVEN
GEIQYPVAEITIAGQLQDMLKNMLAVADDIEHRSNIQTGSILLDKMKISGN

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family

Homologues:

Organism=Escherichia coli, GI1790682, Length=443, Percent_Identity=61.8510158013544, Blast_Score=578, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PMBA_HAEIN (P45077)

Other databases:

- EMBL:   L42023
- PIR:   C64186
- RefSeq:   NP_439310.1
- ProteinModelPortal:   P45077
- SMR:   P45077
- MEROPS:   U62.001
- GeneID:   950115
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1152
- NMPDR:   fig|71421.1.peg.1105
- TIGR:   HI_1152
- HOGENOM:   HBG726714
- OMA:   SRYSLSC
- ProtClustDB:   CLSK869974
- BioCyc:   HINF71421:HI_1152-MONOMER
- GO:   GO:0005737
- InterPro:   IPR002510

Pfam domain/function: PF01523 PmbA_TldD

EC number: NA

Molecular weight: Translated: 48498; Mature: 48498

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCEE
TNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFD
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEC
APDLELYHAADIDVDKATELALQAEQAALQADERIINSNGASFNSHTGVKVYGNSHGMLQ
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHH
SYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLS
HHHCCCCEEEEEEECCHHHHHCCCCEEEEHHHHHHHCCCCEECHHHHHHHHHHCCCCCCC
TREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRR
CCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHH
LASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGG
HHCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHH
LTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVENGEIQYPVAEITIAGQLQDML
HHHHHHHHCCCEEEEHHHCCCCEEEECCCCCCCCCEEEECCEEECCCEEEEEHHHHHHHH
KNMLAVADDIEHRSNIQTGSILLDKMKISGN
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCEE
TNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFD
CCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEC
APDLELYHAADIDVDKATELALQAEQAALQADERIINSNGASFNSHTGVKVYGNSHGMLQ
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHH
SYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLS
HHHCCCCEEEEEEECCHHHHHCCCCEEEEHHHHHHHCCCCEECHHHHHHHHHHCCCCCCC
TREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRR
CCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHH
LASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGG
HHCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHH
LTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVENGEIQYPVAEITIAGQLQDML
HHHHHHHHCCCEEEEHHHCCCCEEEECCCCCCCCCEEEECCEEECCCEEEEEHHHHHHHH
KNMLAVADDIEHRSNIQTGSILLDKMKISGN
HHHHHHHHHHHHHCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800