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The map label for this gene is sodA

Identifier: 16273016

GI number: 16273016

Start: 1152847

End: 1153494

Strand: Reverse

Name: sodA

Synonym: HI1088

Alternate gene names: 16273016

Gene position: 1153494-1152847 (Counterclockwise)

Preceding gene: 30995424

Following gene: 16273015

Centisome position: 63.03

GC content: 39.35

Gene sequence:

>648_bases
ATGTCTTACACTCTCCCTGAATTAGGCTATGCCTACAATGCGTTAGAACCACATTTTGATGCGCAAACAATGGAAATCCA
TCATAGTAAACACCACCAAGCTTACGTAAACAATGCAAATGCTGCATTAGAAGGTTTACCCGCTGAATTAGTAGAAATGT
ATCCGGGTCATTTAATTTCTAACCTTGATAAAATTCCTGCAGAAAAACGTGGAGCATTACGTAATAATGCTGGTGGCCAC
ACAAACCACAGTTTATTTTGGAAAAGCTTGAAAAAAGGCACTACTTTACAAGGCGCATTAAAAGATGCGATTGAACGTGA
TTTCGGTTCTGTAGATGCATTTAAAGCAGAGTTTGAAAAAGCAGCAGCAACTCGTTTTGGTTCTGGTTGGGCGTGGTTAG
TATTAACTGCTGAAGGTAAATTAGCCGTAGTATCAACAGCAAACCAAGATAACCCATTAATGGGTAAAGAAGTGGCAGGT
TGTGAAGGTTTCCCACTTTTAGGTTTAGATGTTTGGGAACACGCTTACTACTTAAAATTCCAAAACCGTCGTCCAGACTA
CATTAAAGAATTCTGGAACGTGGTAAACTGGGATTTCGTTGCAGAACGTTTTGAACAAAAAACAGCACACAGCAATTGCG
CAAAATAA

Upstream 100 bases:

>100_bases
TTTAATGATCTAAATCAATTTTTTTGCTATTATTTGCTCAATTTTGGTTATAGACCAAAACCTCAACGAAATCTGTTTTT
AACAATAGAAGGAATACATT

Downstream 100 bases:

>100_bases
TAAACATAGAAAAGCCTAGCAAAAGCTAGGTTTTTCTACTTTCCTCTCTATAACTTTCCTCTCTATAACTTTCCTCTCTA
TAACTTTTCTCTTGCAATCT

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLISNLDKIPAEKRGALRNNAGGH
TNHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEKAAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAG
CEGFPLLGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK

Sequences:

>Translated_215_residues
MSYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLISNLDKIPAEKRGALRNNAGGH
TNHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEKAAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAG
CEGFPLLGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK
>Mature_214_residues
SYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLISNLDKIPAEKRGALRNNAGGHT
NHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEKAAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAGC
EGFPLLGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family

Homologues:

Organism=Homo sapiens, GI67782307, Length=205, Percent_Identity=47.3170731707317, Blast_Score=180, Evalue=8e-46,
Organism=Homo sapiens, GI67782305, Length=205, Percent_Identity=47.3170731707317, Blast_Score=180, Evalue=8e-46,
Organism=Homo sapiens, GI67782309, Length=203, Percent_Identity=41.3793103448276, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI1790342, Length=207, Percent_Identity=76.8115942028985, Blast_Score=330, Evalue=4e-92,
Organism=Escherichia coli, GI1787946, Length=206, Percent_Identity=43.2038834951456, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17569479, Length=203, Percent_Identity=39.9014778325123, Blast_Score=153, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17506561, Length=203, Percent_Identity=40.3940886699507, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6321796, Length=214, Percent_Identity=40.1869158878505, Blast_Score=142, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17136812, Length=214, Percent_Identity=41.1214953271028, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SODM_HAEIN (P43725)

Other databases:

- EMBL:   X73832
- EMBL:   L42023
- PIR:   C64182
- PIR:   S39871
- RefSeq:   NP_439245.1
- ProteinModelPortal:   P43725
- SMR:   P43725
- GeneID:   950093
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1088
- NMPDR:   fig|71421.1.peg.1045
- TIGR:   HI_1088
- HOGENOM:   HBG507761
- OMA:   WDEVARR
- ProtClustDB:   CLSK808482
- BioCyc:   HINF71421:HI_1088-MONOMER
- BRENDA:   1.15.1.1
- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831
- PANTHER:   PTHR11404
- PIRSF:   PIRSF000349
- PRINTS:   PR01703

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N; SSF46609 SODismutase; SSF54719 SODismutase

EC number: =1.15.1.1

Molecular weight: Translated: 24110; Mature: 23979

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLIS
CCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCHHHH
NLDKIPAEKRGALRNNAGGHTNHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEK
HHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
AAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAGCEGFPLLGLDVWEHAYYLKF
HHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEE
QNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLIS
CCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCHHHH
NLDKIPAEKRGALRNNAGGHTNHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEK
HHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
AAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAGCEGFPLLGLDVWEHAYYLKF
HHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEE
QNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934846; 7542800; 10675023