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The map label for this gene is corA [H]

Identifier: 16272969

GI number: 16272969

Start: 1099920

End: 1100867

Strand: Direct

Name: corA [H]

Synonym: HI1035

Alternate gene names: 16272969

Gene position: 1099920-1100867 (Clockwise)

Preceding gene: 16272968

Following gene: 30995418

Centisome position: 60.1

GC content: 38.4

Gene sequence:

>948_bases
ATGATCAACGCGTTTGCTATCAATGATTCCCGCTTGGTTCGCATTGACGAAGACCAAACTGATCTCAATACTGCCATTTG
GCTTGATTTACTTGAGCCGACAGGCGAAGAACGTGAAATGCTACAAGAAGGCTTAGGCCAGAGCCTAGCATCTTTTCTAG
AACTGGAAGATATCGAGGCTTCCGCCCGTTTCTTTGAAGACGAAGATGGTTTACACCTTCACTCATTTTTTTATTGCGAA
GATGAAGACAATTATGCTGATTTAGCGAGCGTCGCTTTTACTATTCGTGATGGTCGTTTATTTACGTTGCGTGATCGCGA
GCTACCAGCATTCCGTTTATATCGTATGCGTTCACGTAGCCAGCGTTTGTTAGAATGCAATTCCTATGAAGTTTTACTGG
ATTTATTTGAAACGAAAATTGAGCAATTAGCGGACGTGATTGAAAATATCTATGCAGATTTGGAAGAGTTAAGTCGTGTT
ATTTTAAACGGAAAACAAGATGAAGCCTTTGATGAAGCATTAAATACACTCACGGAACAAGAAGATACGAGCTCAAAAGT
TCGTTTGTGCTTGATGGATACTCAACGTGCATTAGGTTTCTTGGTTCGCAAAACTCGCTTACCAACTAATCAGTTAGAAC
AAGCACGAGAAATCTTACGAGATATTGAATCTTTGCAACCGCATAATGAATCATTATTCCAAAAAGTAAACTTTTTAATG
CAAGCTGCAATGGGTTACATCAATATTGAACAGAACAAAATTATGAAATTCTTCTCAGTTGTTTCTGTGATGTTCCTTCC
TGCAACATTAGTTGCATCCACTTATGGTATGAACTTTGATTTTATGCCTGAGTTACATTTTAAATATGGCTATCCAATGG
CAATTGGATTAATGATCGCAGCCGCATTGACACCATATATTTATTTTAGAAGAAAAGGATGGCTATGA

Upstream 100 bases:

>100_bases
CGGCATCTCTTAACGAAAACTTTGCGATTTTTCACCGCACTTTCGTTTCTTCTTTAATTTGTTCACTGTTAGCTGTTCAT
AATCCTATAAGGAGTATGAA

Downstream 100 bases:

>100_bases
TGGAATTATCCCAAACCGCATTATTTATCGGATCAATTATTAATCTTAACGCACTTGTATTAATCTTACGAGCTTGGTTG
CAGTTTGCTCGTGTGGATTA

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL

Sequences:

>Translated_315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL
>Mature_315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=316, Percent_Identity=70.253164556962, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36594; Mature: 36594

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEA
CCEEEEECCCEEEEECCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SARFFEDEDGLHLHSFFYCEDEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRS
HHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHHH
QRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRVILNGKQDEAFDEALNTLTEQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
EDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
CCCCHHEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIA
HHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHH
AALTPYIYFRRKGWL
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREMLQEGLGQSLASFLELEDIEA
CCEEEEECCCEEEEECCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SARFFEDEDGLHLHSFFYCEDEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRS
HHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHHH
QRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRVILNGKQDEAFDEALNTLTEQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
EDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
CCCCHHEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIA
HHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHH
AALTPYIYFRRKGWL
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA