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The map label for this gene is tbp1

Identifier: 16272932

GI number: 16272932

Start: 1057465

End: 1060203

Strand: Reverse

Name: tbp1

Synonym: HI0994

Alternate gene names: 16272932

Gene position: 1060203-1057465 (Counterclockwise)

Preceding gene: 16272933

Following gene: 16272931

Centisome position: 57.93

GC content: 35.82

Gene sequence:

>2739_bases
ATGACTAAAAAACCCTATTTTCGCCTAAGTATTATTTCTTGTCTTTTAATTTCATGCTATGTAAAAGCAGAAACTCAAAG
TATAAAAGATACAAAAGAAGCTATATCATCTGAAGTGGACACTCAAAGTACAGAAGATTCAGAATTAGAAACTATCTCAG
TCACTGCAGAAAAAGTAAGAGATCGTAAAGATAATGAAGTAACTGGACTTGGCAAAATTATCAAAACTAGTGAAAGTATC
AGCCGAGAACAAGTATTAAATATTCGTGATCTAACACGCTATGATCCAGGGATTTCAGTTGTAGAACAAGGTCGCGGTGC
AAGTTCTGGATATTCTATTCGTGGTATGGACAGAAATAGAGTTGCTTTATTGGTAGATGGTTTACCTCAAACGCAATCTT
ATGTAGTGCAAAGCCCTTTAGTTGCTCGTTCAGGATATTCTGGCACTGGTGCAATTAATGAAATTGAATATGAAAATGTA
AAGGCCGTCGAAATAAGCAAGGGGGGGAGTTCTTCTGAGTATGGAAATGGAGCATTAGCTGGTTCTGTAACATTTCAAAG
CAAATCCGCAGCCGATATCTTAGAAGGAGACAAATCATGGGGAATTCAAACTAAAAATGCTTATTCAAGCAAAAATAAAG
GCTTTACCCATTCTTTAGCTGTAGCAGGAAAACAAGGTGGATTTGAAGGACTTGCTATTTACACTCAACGAAATTCAATT
GAAACCCAAGTCCATAAAGATGCATTAAAAGGCGTGCAAAGTTATAATCGCTTAATCGCCAAACCAGAGAATCAATCTGC
ATACTTTGTGATGGAAGATGAGTGTCCAAAGGGTTATGACGAGTGTATACCTTCAGCCAAACCACCTGCGATTTTATCCA
CCAAAAAAGAAACCGTAAGCGTTTCAGATTATACGGGGGCTAACCGTATCAAACCTAATCCAATGAAATATGAAAGCCAG
TCTTGGTTTTTAAGAGGAGGGTATCATTTTTCTGAACAACATTATATTGGTGGTATTTTTGAATTCACACAACAAAAATT
TGATATCCGTGATATGACATTTCCCGCTTATTTAAGCCCAACAGAAAAAGGGGATTTAGCAAATCGCCCTTTTTATCCAA
AGCAAGATTATGGCGCATATCAACATATTGAGGATGGCCGAGGCGTTAAATATGCAAGTGGGCTTTATTTCGATGAACAC
CATAGAAAACAGCGTGTAGGTATTGAATATATTTACGAAAATAAGAACAAAGCGGGCATCATTGACAAAGCAGTGTTAAG
TGCTAATCAACAAAACATCATACTTGACAGTTATATGCGACATACGCATTGCAGTCTTTATCCTAATCCAAGTAAGAATT
GCCGCCCAACACTTGATAAACCTTATTCATACTATCGTTCTGATAGAAATGTTTATAAAGAAAAACATAATATGTTGCAA
TTGAATTTAGAGAAAAAAATTCAACAAAATTGGCTTACTCATCAAATTGTCTTCAATCTTGGTTTTGATGACTTTACTTC
CGCACTTCAGCATAAAGATTATTTAACTCGACGTGTTATCGCTACGGCAGATAGTATTTCAGATAAAACTGGTAAAACAA
GAAGAAATGGTTTACGCGAATACCCTTACTTATACCCAAAACCAAAGCCATATTTTGCAGGAGAAGATCATTGTAATTAT
CAAGGTAGTTCCTCTAATTACAGAGACTGTAAAGTGCGGTTAATTAAAGGGAAAAATTATTATTTCGCAGCACGCAATAA
TATGGCATTAGGGAAATACGTTGATTTAGGTTTAGGTATTCGGTATGACGTATCTCGTACAAAAGCTAATGAATCAACTA
TTAGTGTTGGTAAATTTAAAAATTTCTCTTGGAATACTGGTATTGTCATAAAACCAACGGAATGGCTTGATCTTTCTTAT
CGCCTTTCTACTGGATTTAGAAATCCTAGTTTTGCTGAAATGTATGGTTGGCGGTATGGTGGCAAGAATGACGAGGTTTA
TGTAGGTAAATTTAAGCCTGAAACATCTCGTAACCAAGAGTTTGGTCTCGCTCTAAAAGGGGATTTTGGTAATATTGAGA
TCAGTCATTTTAGTAATGCTTATCGAAATCTTATCGCCTTTGCTGAAGAACTTAGTAAAAATGGAACTGGAAAGGGCAAT
TATGGATATCATAATGCACAAAATGCAAAATTAGTTGGTGTAAATATAACTGCGCAATTAGATTTTAATGGTTTATGGAA
ACGTATTCCCTACGGTTGGTATGCAACATTTGCTTATAACCGAGTAAAAGTTAAAGATCAAAAAATCAATGCTGGTTTAG
CCTCCGTAAGCAGTTATTTATTTGATGCCATTCAGCCCAGCCGTTATATCATTGGTTTAGGCTATGATCATATAAGTAAT
ACTTGGGGAGTAAATGCTACCTTTACCCAATCAAAAGCAAAATCTCAAAATGAATTGCTAGGAAAACGTGCATTAGGTAA
CAATTCAAGGGATGTAAAATCAACAAGAAAACTTACTCGGGCATGGCATATCTTAGATGTATCGGGTTATTACATGGCGA
ATAAAAATATTATGCTTCGATTAGGGATATATAATTTATTCAACTATCGTTATGTTACTTGGGAAGCGGTGCGTCAAACA
GCACAAGGTGCGGTCAATCAACATCAAAATGTTGGTAACTATACTCGCTACGCAGCATCAGGACGAAACTATACCTTAAC
ATTAGAAATGAAATTCTAA

Upstream 100 bases:

>100_bases
ATCCAATTCAGAAAAGGCAAGAGCTGCAGTTGTGTTTGGAGCTAAAAAACAAGTAGAAACAAACAACAAGTAGAAACAAC
CAAATAATGGAATACTAAAA

Downstream 100 bases:

>100_bases
ATTAAAATGCGCCAGATAGATTAAATATGCTATATCTATACAATACTGGCGCATTTTTTTCTGTTCTATAATCTGCTTAA
GTGAAAGGTCAAACTTGGAT

Product: transferrin-binding protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 912; Mature: 911

Protein sequence:

>912_residues
MTKKPYFRLSIISCLLISCYVKAETQSIKDTKEAISSEVDTQSTEDSELETISVTAEKVRDRKDNEVTGLGKIIKTSESI
SREQVLNIRDLTRYDPGISVVEQGRGASSGYSIRGMDRNRVALLVDGLPQTQSYVVQSPLVARSGYSGTGAINEIEYENV
KAVEISKGGSSSEYGNGALAGSVTFQSKSAADILEGDKSWGIQTKNAYSSKNKGFTHSLAVAGKQGGFEGLAIYTQRNSI
ETQVHKDALKGVQSYNRLIAKPENQSAYFVMEDECPKGYDECIPSAKPPAILSTKKETVSVSDYTGANRIKPNPMKYESQ
SWFLRGGYHFSEQHYIGGIFEFTQQKFDIRDMTFPAYLSPTEKGDLANRPFYPKQDYGAYQHIEDGRGVKYASGLYFDEH
HRKQRVGIEYIYENKNKAGIIDKAVLSANQQNIILDSYMRHTHCSLYPNPSKNCRPTLDKPYSYYRSDRNVYKEKHNMLQ
LNLEKKIQQNWLTHQIVFNLGFDDFTSALQHKDYLTRRVIATADSISDKTGKTRRNGLREYPYLYPKPKPYFAGEDHCNY
QGSSSNYRDCKVRLIKGKNYYFAARNNMALGKYVDLGLGIRYDVSRTKANESTISVGKFKNFSWNTGIVIKPTEWLDLSY
RLSTGFRNPSFAEMYGWRYGGKNDEVYVGKFKPETSRNQEFGLALKGDFGNIEISHFSNAYRNLIAFAEELSKNGTGKGN
YGYHNAQNAKLVGVNITAQLDFNGLWKRIPYGWYATFAYNRVKVKDQKINAGLASVSSYLFDAIQPSRYIIGLGYDHISN
TWGVNATFTQSKAKSQNELLGKRALGNNSRDVKSTRKLTRAWHILDVSGYYMANKNIMLRLGIYNLFNYRYVTWEAVRQT
AQGAVNQHQNVGNYTRYAASGRNYTLTLEMKF

Sequences:

>Translated_912_residues
MTKKPYFRLSIISCLLISCYVKAETQSIKDTKEAISSEVDTQSTEDSELETISVTAEKVRDRKDNEVTGLGKIIKTSESI
SREQVLNIRDLTRYDPGISVVEQGRGASSGYSIRGMDRNRVALLVDGLPQTQSYVVQSPLVARSGYSGTGAINEIEYENV
KAVEISKGGSSSEYGNGALAGSVTFQSKSAADILEGDKSWGIQTKNAYSSKNKGFTHSLAVAGKQGGFEGLAIYTQRNSI
ETQVHKDALKGVQSYNRLIAKPENQSAYFVMEDECPKGYDECIPSAKPPAILSTKKETVSVSDYTGANRIKPNPMKYESQ
SWFLRGGYHFSEQHYIGGIFEFTQQKFDIRDMTFPAYLSPTEKGDLANRPFYPKQDYGAYQHIEDGRGVKYASGLYFDEH
HRKQRVGIEYIYENKNKAGIIDKAVLSANQQNIILDSYMRHTHCSLYPNPSKNCRPTLDKPYSYYRSDRNVYKEKHNMLQ
LNLEKKIQQNWLTHQIVFNLGFDDFTSALQHKDYLTRRVIATADSISDKTGKTRRNGLREYPYLYPKPKPYFAGEDHCNY
QGSSSNYRDCKVRLIKGKNYYFAARNNMALGKYVDLGLGIRYDVSRTKANESTISVGKFKNFSWNTGIVIKPTEWLDLSY
RLSTGFRNPSFAEMYGWRYGGKNDEVYVGKFKPETSRNQEFGLALKGDFGNIEISHFSNAYRNLIAFAEELSKNGTGKGN
YGYHNAQNAKLVGVNITAQLDFNGLWKRIPYGWYATFAYNRVKVKDQKINAGLASVSSYLFDAIQPSRYIIGLGYDHISN
TWGVNATFTQSKAKSQNELLGKRALGNNSRDVKSTRKLTRAWHILDVSGYYMANKNIMLRLGIYNLFNYRYVTWEAVRQT
AQGAVNQHQNVGNYTRYAASGRNYTLTLEMKF
>Mature_911_residues
TKKPYFRLSIISCLLISCYVKAETQSIKDTKEAISSEVDTQSTEDSELETISVTAEKVRDRKDNEVTGLGKIIKTSESIS
REQVLNIRDLTRYDPGISVVEQGRGASSGYSIRGMDRNRVALLVDGLPQTQSYVVQSPLVARSGYSGTGAINEIEYENVK
AVEISKGGSSSEYGNGALAGSVTFQSKSAADILEGDKSWGIQTKNAYSSKNKGFTHSLAVAGKQGGFEGLAIYTQRNSIE
TQVHKDALKGVQSYNRLIAKPENQSAYFVMEDECPKGYDECIPSAKPPAILSTKKETVSVSDYTGANRIKPNPMKYESQS
WFLRGGYHFSEQHYIGGIFEFTQQKFDIRDMTFPAYLSPTEKGDLANRPFYPKQDYGAYQHIEDGRGVKYASGLYFDEHH
RKQRVGIEYIYENKNKAGIIDKAVLSANQQNIILDSYMRHTHCSLYPNPSKNCRPTLDKPYSYYRSDRNVYKEKHNMLQL
NLEKKIQQNWLTHQIVFNLGFDDFTSALQHKDYLTRRVIATADSISDKTGKTRRNGLREYPYLYPKPKPYFAGEDHCNYQ
GSSSNYRDCKVRLIKGKNYYFAARNNMALGKYVDLGLGIRYDVSRTKANESTISVGKFKNFSWNTGIVIKPTEWLDLSYR
LSTGFRNPSFAEMYGWRYGGKNDEVYVGKFKPETSRNQEFGLALKGDFGNIEISHFSNAYRNLIAFAEELSKNGTGKGNY
GYHNAQNAKLVGVNITAQLDFNGLWKRIPYGWYATFAYNRVKVKDQKINAGLASVSSYLFDAIQPSRYIIGLGYDHISNT
WGVNATFTQSKAKSQNELLGKRALGNNSRDVKSTRKLTRAWHILDVSGYYMANKNIMLRLGIYNLFNYRYVTWEAVRQTA
QGAVNQHQNVGNYTRYAASGRNYTLTLEMKF

Specific function: Acts as a transferrin receptor and is required for transferrin utilization

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TBPA_HAEIN (P44970)

Other databases:

- EMBL:   L42023
- PIR:   C64107
- RefSeq:   NP_439157.1
- ProteinModelPortal:   P44970
- SMR:   P44970
- GeneID:   950660
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0994
- NMPDR:   fig|71421.1.peg.961
- TIGR:   HI_0994
- HOGENOM:   HBG296544
- OMA:   EIEYENV
- ProtClustDB:   CLSK877571
- BioCyc:   HINF71421:HI_0994-MONOMER
- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010949
- InterPro:   IPR010948
- InterPro:   IPR010917
- Gene3D:   G3DSA:2.170.130.10
- Gene3D:   G3DSA:2.40.170.20
- TIGRFAMs:   TIGR01786
- TIGRFAMs:   TIGR01776

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec

EC number: NA

Molecular weight: Translated: 103235; Mature: 103104

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00430 TONB_DEPENDENT_REC_1; PS01156 TONB_DEPENDENT_REC_2; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKPYFRLSIISCLLISCYVKAETQSIKDTKEAISSEVDTQSTEDSELETISVTAEKVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHH
DRKDNEVTGLGKIIKTSESISREQVLNIRDLTRYDPGISVVEQGRGASSGYSIRGMDRNR
CCCCCCHHHHHHHHHCHHHHCHHHHCCHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCC
VALLVDGLPQTQSYVVQSPLVARSGYSGTGAINEIEYENVKAVEISKGGSSSEYGNGALA
EEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCEEE
GSVTFQSKSAADILEGDKSWGIQTKNAYSSKNKGFTHSLAVAGKQGGFEGLAIYTQRNSI
EEEEECCCCCHHHHCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCH
ETQVHKDALKGVQSYNRLIAKPENQSAYFVMEDECPKGYDECIPSAKPPAILSTKKETVS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCEEECCCCEEE
VSDYTGANRIKPNPMKYESQSWFLRGGYHFSEQHYIGGIFEFTQQKFDIRDMTFPAYLSP
ECCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCCHHHHHHHHCCCCCCCCCCCEECC
TEKGDLANRPFYPKQDYGAYQHIEDGRGVKYASGLYFDEHHRKQRVGIEYIYENKNKAGI
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCEEHHHHHHHHCCEEEEEECCCCCCC
IDKAVLSANQQNIILDSYMRHTHCSLYPNPSKNCRPTLDKPYSYYRSDRNVYKEKHNMLQ
HHHHHHCCCCCCEEHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHCHHHHHHHHCCEEE
LNLEKKIQQNWLTHQIVFNLGFDDFTSALQHKDYLTRRVIATADSISDKTGKTRRNGLRE
EEHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
YPYLYPKPKPYFAGEDHCNYQGSSSNYRDCKVRLIKGKNYYFAARNNMALGKYVDLGLGI
CCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCEECCEEEECCCE
RYDVSRTKANESTISVGKFKNFSWNTGIVIKPTEWLDLSYRLSTGFRNPSFAEMYGWRYG
EEECCCCCCCCCEEEECCCCCCCCCCCEEECCCHHEEEEEEEECCCCCCCHHHHHCEECC
GKNDEVYVGKFKPETSRNQEFGLALKGDFGNIEISHFSNAYRNLIAFAEELSKNGTGKGN
CCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
YGYHNAQNAKLVGVNITAQLDFNGLWKRIPYGWYATFAYNRVKVKDQKINAGLASVSSYL
CCCCCCCCCEEEEEEEEEEECCCHHHHHCCCCEEEEEEEEEEEEECCHHHCHHHHHHHHH
FDAIQPSRYIIGLGYDHISNTWGVNATFTQSKAKSQNELLGKRALGNNSRDVKSTRKLTR
HHHCCCCCEEEEECHHHCCCCCCCCEEECHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHH
AWHILDVSGYYMANKNIMLRLGIYNLFNYRYVTWEAVRQTAQGAVNQHQNVGNYTRYAAS
HEEEEEECCEEEECCCEEEEEEEEHHHCEEEEEHHHHHHHHHHHHHHHCCCCCHHEEEEC
GRNYTLTLEMKF
CCCEEEEEEEEC
>Mature Secondary Structure 
TKKPYFRLSIISCLLISCYVKAETQSIKDTKEAISSEVDTQSTEDSELETISVTAEKVR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHH
DRKDNEVTGLGKIIKTSESISREQVLNIRDLTRYDPGISVVEQGRGASSGYSIRGMDRNR
CCCCCCHHHHHHHHHCHHHHCHHHHCCHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCC
VALLVDGLPQTQSYVVQSPLVARSGYSGTGAINEIEYENVKAVEISKGGSSSEYGNGALA
EEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCCCCCEEE
GSVTFQSKSAADILEGDKSWGIQTKNAYSSKNKGFTHSLAVAGKQGGFEGLAIYTQRNSI
EEEEECCCCCHHHHCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCH
ETQVHKDALKGVQSYNRLIAKPENQSAYFVMEDECPKGYDECIPSAKPPAILSTKKETVS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHCCCCCCCCEEECCCCEEE
VSDYTGANRIKPNPMKYESQSWFLRGGYHFSEQHYIGGIFEFTQQKFDIRDMTFPAYLSP
ECCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCCCHHHHHHHHCCCCCCCCCCCEECC
TEKGDLANRPFYPKQDYGAYQHIEDGRGVKYASGLYFDEHHRKQRVGIEYIYENKNKAGI
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCEEHHHHHHHHCCEEEEEECCCCCCC
IDKAVLSANQQNIILDSYMRHTHCSLYPNPSKNCRPTLDKPYSYYRSDRNVYKEKHNMLQ
HHHHHHCCCCCCEEHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHCHHHHHHHHCCEEE
LNLEKKIQQNWLTHQIVFNLGFDDFTSALQHKDYLTRRVIATADSISDKTGKTRRNGLRE
EEHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
YPYLYPKPKPYFAGEDHCNYQGSSSNYRDCKVRLIKGKNYYFAARNNMALGKYVDLGLGI
CCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCEECCEEEECCCE
RYDVSRTKANESTISVGKFKNFSWNTGIVIKPTEWLDLSYRLSTGFRNPSFAEMYGWRYG
EEECCCCCCCCCEEEECCCCCCCCCCCEEECCCHHEEEEEEEECCCCCCCHHHHHCEECC
GKNDEVYVGKFKPETSRNQEFGLALKGDFGNIEISHFSNAYRNLIAFAEELSKNGTGKGN
CCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
YGYHNAQNAKLVGVNITAQLDFNGLWKRIPYGWYATFAYNRVKVKDQKINAGLASVSSYL
CCCCCCCCCEEEEEEEEEEECCCHHHHHCCCCEEEEEEEEEEEEECCHHHCHHHHHHHHH
FDAIQPSRYIIGLGYDHISNTWGVNATFTQSKAKSQNELLGKRALGNNSRDVKSTRKLTR
HHHCCCCCEEEEECHHHCCCCCCCCEEECHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHH
AWHILDVSGYYMANKNIMLRLGIYNLFNYRYVTWEAVRQTAQGAVNQHQNVGNYTRYAAS
HEEEEEECCEEEECCCEEEEEEEEHHHCEEEEEHHHHHHHHHHHHHHHCCCCCHHEEEEC
GRNYTLTLEMKF
CCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800