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The map label for this gene is tsf [H]

Identifier: 16272851

GI number: 16272851

Start: 968775

End: 969626

Strand: Direct

Name: tsf [H]

Synonym: HI0914

Alternate gene names: 16272851

Gene position: 968775-969626 (Clockwise)

Preceding gene: 161350022

Following gene: 16272858

Centisome position: 52.93

GC content: 39.67

Gene sequence:

>852_bases
ATGGCTGAAATCACAGCATCATTAGTAAAAGAACTTCGTGACCGTACTGGCGCAGGTATGATGGAATGTAAAAAAGCATT
AGTTGAAGCAAACGGTGATATTGAGTTAGCAATCGACAATATGCGTAAATCTGGTCAAGCTAAAGCAGCTAAAAAAGCAG
GCCGTGTTGCAGCTGAAGGTGTTATCCTTGCTCGTGTAGAAAATGGTTTCGGTGTATTAGTTGAAATGAACTGTGAAACT
GACTTCGTAGCAAAAGATGCAGGTTTCTTAGGTTTAGCAAATGAAGTAACTGATTTCGCAGCAGCAAACAAAGGTACCAC
TATCGAAGCATTACAAGCGCAATTTGAAGAAAAACGTGCTGCATTAGTTGCTAAAATCGGTGAGAACATGAATATTCGTC
GTGTTGCTTACCTAGATGGTCAAGTAATTGCACAATACTTACACGGTGCAAAAATTGGCGTATTAGTTGCGGGCGAAGGT
TCTGCTGATGAACTGAAAAAAGTAGCAATGCACGTAGCTGCATCTAAACCTGAATTCGTGAACCCAGAAGATGTATCTGC
TGAAGTGGTTGAACACGAACGCCAAATCCAAATCGATATTGCGATCAACTCTGGTAAACCAAAAGAAATCGCAGAGAAAA
TGGTTGAAGGTCGTATGAAGAAATTCACTGGTGAAGTTTCATTAACAGGTCAAGCATTTGTAATGGATCCTTCTGTATCT
GTAGGGGATTTCTTAAAATCAGTAAATACTTCTGTTTCTAACTTCATTCGTTTAGAAGTAGGCGAAGGTATTGAGAAAAA
AGAAGAAGATTTTGCTGCTGAAGTTGCAAAAATCACTGGCGGTAATGCGTAA

Upstream 100 bases:

>100_bases
ATCAAGCGATTAATTGGCATAGGGGCTAAAATTTAGCCCCTATATTTTTATCTAAAAGTGCGGTCAAAATAAACCGCATT
TTCGACAGAGGATTTTAAAA

Downstream 100 bases:

>100_bases
TTCTTTAAAGATAACGATATGTTAATAAGCCCAACTTAAGTTGGGCTTATTTGTTTTATAGGATAAGCTGCTTAATTAAC
GGGCTTAAACTTTTTTAGTT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAEITASLVKELRDRTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILARVENGFGVLVEMNCET
DFVAKDAGFLGLANEVTDFAAANKGTTIEALQAQFEEKRAALVAKIGENMNIRRVAYLDGQVIAQYLHGAKIGVLVAGEG
SADELKKVAMHVAASKPEFVNPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVS
VGDFLKSVNTSVSNFIRLEVGEGIEKKEEDFAAEVAKITGGNA

Sequences:

>Translated_283_residues
MAEITASLVKELRDRTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILARVENGFGVLVEMNCET
DFVAKDAGFLGLANEVTDFAAANKGTTIEALQAQFEEKRAALVAKIGENMNIRRVAYLDGQVIAQYLHGAKIGVLVAGEG
SADELKKVAMHVAASKPEFVNPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVS
VGDFLKSVNTSVSNFIRLEVGEGIEKKEEDFAAEVAKITGGNA
>Mature_282_residues
AEITASLVKELRDRTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILARVENGFGVLVEMNCETD
FVAKDAGFLGLANEVTDFAAANKGTTIEALQAQFEEKRAALVAKIGENMNIRRVAYLDGQVIAQYLHGAKIGVLVAGEGS
ADELKKVAMHVAASKPEFVNPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVSV
GDFLKSVNTSVSNFIRLEVGEGIEKKEEDFAAEVAKITGGNA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=284, Percent_Identity=27.8169014084507, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI291084500, Length=305, Percent_Identity=25.2459016393443, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI291084498, Length=93, Percent_Identity=41.9354838709677, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI291084502, Length=93, Percent_Identity=41.9354838709677, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786366, Length=280, Percent_Identity=71.4285714285714, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17561440, Length=292, Percent_Identity=24.6575342465753, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921466, Length=289, Percent_Identity=28.719723183391, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 30188; Mature: 30057

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITASLVKELRDRTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCHHHCC
VILARVENGFGVLVEMNCETDFVAKDAGFLGLANEVTDFAAANKGTTIEALQAQFEEKRA
EEEEEEECCCEEEEEECCCCCEEECCCCCEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ALVAKIGENMNIRRVAYLDGQVIAQYLHGAKIGVLVAGEGSADELKKVAMHVAASKPEFV
HHHHHHCCCCCEEEEEEECHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
NPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVS
CCCCCHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCC
VGDFLKSVNTSVSNFIRLEVGEGIEKKEEDFAAEVAKITGGNA
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEITASLVKELRDRTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCHHHCC
VILARVENGFGVLVEMNCETDFVAKDAGFLGLANEVTDFAAANKGTTIEALQAQFEEKRA
EEEEEEECCCEEEEEECCCCCEEECCCCCEECHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ALVAKIGENMNIRRVAYLDGQVIAQYLHGAKIGVLVAGEGSADELKKVAMHVAASKPEFV
HHHHHHCCCCCEEEEEEECHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCC
NPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVS
CCCCCHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCC
VGDFLKSVNTSVSNFIRLEVGEGIEKKEEDFAAEVAKITGGNA
HHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA