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The map label for this gene is tadA

Identifier: 16272843

GI number: 16272843

Start: 960362

End: 960883

Strand: Direct

Name: tadA

Synonym: HI0906

Alternate gene names: 16272843

Gene position: 960362-960883 (Clockwise)

Preceding gene: 16272842

Following gene: 16272845

Centisome position: 52.47

GC content: 40.8

Gene sequence:

>522_bases
ATGGATGCAGCAAAAGTGCGGTCAGAATTTGACGAGAAAATGATGCGCTACGCCCTTGAGCTTGCCGATAAAGCGGAAGC
GTTAGGTGAGATTCCTGTGGGGGCGGTGCTGGTGGATGACGCTAGAAATATTATTGGAGAAGGTTGGAATCTCTCCATTG
TTCAAAGTGATCCTACTGCACATGCTGAAATTATCGCTTTGCGTAATGGTGCGAAAAATATTCAAAATTATCGCCTACTG
AATAGCACGCTTTATGTGACATTAGAGCCTTGCACAATGTGCGCAGGGGCAATTTTGCATAGCCGTATTAAACGTCTTGT
GTTCGGTGCATCTGATTATAAAACTGGCGCGATTGGATCACGTTTTCATTTTTTTGATGATTACAAGATGAATCATACTT
TAGAGGTTACATCTGGCGTATTGGCAGAAGAGTGTAGTCAAAAATTGAGTACATTTTTTCAGAAAAGACGCGAGGAGAAA
AAAATAGAGAAAGCATTATTAAAAAGTCTGAGTGATAAGTAA

Upstream 100 bases:

>100_bases
TAAAAACGCTTGAAGATTTGGAAACTTGGGTCACGATGGATGATTTTAAAGTCGTTGGCTATCAATCCCACGAACCAATT
AAATATCCTTTTTCCGTCTA

Downstream 100 bases:

>100_bases
TTCTTTATTTTTTCTTATATTTGAAACTTAAAATCCAGGATTGATCGTTATCTCAAATCCTGTTACTTGCGGAAACTCTT
CTTGAATGAGTTTCAACAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTAHAEIIALRNGAKNIQNYRLL
NSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGSRFHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEK
KIEKALLKSLSDK

Sequences:

>Translated_173_residues
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTAHAEIIALRNGAKNIQNYRLL
NSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGSRFHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEK
KIEKALLKSLSDK
>Mature_173_residues
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTAHAEIIALRNGAKNIQNYRLL
NSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGSRFHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEK
KIEKALLKSLSDK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Homo sapiens, GI124107608, Length=162, Percent_Identity=30.2469135802469, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI145693172, Length=153, Percent_Identity=58.8235294117647, Blast_Score=184, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17554608, Length=120, Percent_Identity=40.8333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=33.5526315789474, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=96, Percent_Identity=36.4583333333333, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=110, Percent_Identity=33.6363636363636, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TADA_HAEIN (P44931)

Other databases:

- EMBL:   L42023
- PIR:   C64161
- RefSeq:   NP_439066.1
- ProteinModelPortal:   P44931
- SMR:   P44931
- GeneID:   949908
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0906
- NMPDR:   fig|71421.1.peg.872
- TIGR:   HI_0906
- HOGENOM:   HBG741046
- OMA:   DACSAQL
- ProtClustDB:   CLSK869954
- BioCyc:   HINF71421:HI_0906-MONOMER
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193

Pfam domain/function: PF00383 dCMP_cyt_deam_1; SSF53927 Cytidine_deaminase-like

EC number: NA

Molecular weight: Translated: 19359; Mature: 19359

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCEEEEECCCCC
HAEIIALRNGAKNIQNYRLLNSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGS
HHHHEEECCCHHHHHHHEEECCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEKKIEKALLKSLSDK
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDAAKVRSEFDEKMMRYALELADKAEALGEIPVGAVLVDDARNIIGEGWNLSIVQSDPTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCEEEEECCCCC
HAEIIALRNGAKNIQNYRLLNSTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAIGS
HHHHEEECCCHHHHHHHEEECCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFHFFDDYKMNHTLEVTSGVLAEECSQKLSTFFQKRREEKKIEKALLKSLSDK
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800