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The map label for this gene is secY

Identifier: 16272739

GI number: 16272739

Start: 849035

End: 850360

Strand: Direct

Name: secY

Synonym: HI0798

Alternate gene names: 16272739

Gene position: 849035-850360 (Clockwise)

Preceding gene: 16272738

Following gene: 16272740

Centisome position: 46.39

GC content: 36.12

Gene sequence:

>1326_bases
ATGGCTAAACAACCAGGTTATCAAGCAAGAAGTACTAATAGCGGTAAAGGTGAATTAAAAAGCCGATTACTTTTCGTTTT
AGGTGCACTTATCGTTTATCGAATTGGTTCATTCATTCCGGTTCCTGGTATTGATGCGGCTGTTCTAGCTCAATTAGTTG
AACAACAAAAAGGCACTATCATTGACATGTTTAACATGTTCTCTGGTGGTGCTCTAAGCCGTGCATCCATTTTAGCATTA
GGAATCATGCCATATATATCGGCATCTATTGTAATTCAATTGCTTGCAACGGTTTCTCCTGCTTTAGCAGAATTAAAGAA
AGAAGGTGCTGCTGGTCAGCGTAAAATTTCTAAATATACTCGTTATGCGACAGTTGTTTTTGCAACGATTCAGGCAGTAG
CTATTTCAACAGGCTTACCAAATATGTTGTCTGGCTTAGTGCCAAATGTTGGATTTAGTTTTTACTTCACTTCAGTTGTT
AGTTTAGTCACTGGGACAATGTTCCTTATGTGGTTGGGTGAGCAAATAACTGAAAGAGGTATTGGTAACGGTATTTCAAT
TCTTGTTTTTGGCGGTATTGTAGCTGGTTTACCATCGGCTATTCTTCAAACTATTGAGCAGGCTCGTCAAGGACAGATGC
ATCCATTAGTTCTTCTTCTGATCGCAGCTATTGTATTTGCAGTAACTTATTTTGTTGTTTTTGTTGAAAGAGGACAACGT
AGAATTCGCGTTGAATATGCGAAGCGTCAGCAAGGTCGTCAAATTTTAGGTGGTCATTCAACACATTTACCATTGAAAGT
GAATATGGCAAATGTAATGCCAGCAATTTTTGCTTCAAGTATTATTTTATTCCCAGCTACATTAACACAATGGTTTGGGC
AAAATGATAAATTTGAATGGTTAAATAATTTATCAATGTTATTGAATCCTGGTCAACCACTTTATTTGCTTGTTTATGCT
GTTGCAATTATTTTCTTCAGCTTTTTCTATACAGCAATGCAATATAATCCTCGTGATACAGCAGATAATCTAAAAAAATC
TGGTGCATTTATTCCAGGAATTAGACCCGGTGAACAAACATCACGTTATATTGATAAAGTGATGACTCGTCTTACATTAA
TTGGCGGTCTCTATGTAACGTTTGTATGTTTAGTTCCTTATATTATGACATCGGCTTGGGATGTTAAATTTTACTTCGGT
GGAACATCTCTTTTAATTGTAGTCGTTGTAATTATGGATTTCATCGTTCAGGTTCAAAGTCATTTAATGTCTTCTCAATA
TGAATCTGCGTTGAAAAAAGCAAACCTTAAAGGTTTTGGACAATAA

Upstream 100 bases:

>100_bases
GAAGTGAAATCTGCAGTAACGGTACGCGGTTTACGTGTAACTAAAGGTGCAAAAGCAGCAATTGAAGCTGCTGGCGGTTC
AATTGAGGAATAATTAGCAA

Downstream 100 bases:

>100_bases
TTGTTCATTTAAAGTAAAAGGATAAGCAATGAAAGTTCGTGCTTCCGTAAAGAAAATGTGTCGTAACTGTAAGATTGTTA
AACGTGAGGGTGTTGTACGC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAKQPGYQARSTNSGKGELKSRLLFVLGALIVYRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASILAL
GIMPYISASIVIQLLATVSPALAELKKEGAAGQRKISKYTRYATVVFATIQAVAISTGLPNMLSGLVPNVGFSFYFTSVV
SLVTGTMFLMWLGEQITERGIGNGISILVFGGIVAGLPSAILQTIEQARQGQMHPLVLLLIAAIVFAVTYFVVFVERGQR
RIRVEYAKRQQGRQILGGHSTHLPLKVNMANVMPAIFASSIILFPATLTQWFGQNDKFEWLNNLSMLLNPGQPLYLLVYA
VAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKVMTRLTLIGGLYVTFVCLVPYIMTSAWDVKFYFG
GTSLLIVVVVIMDFIVQVQSHLMSSQYESALKKANLKGFGQ

Sequences:

>Translated_441_residues
MAKQPGYQARSTNSGKGELKSRLLFVLGALIVYRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASILAL
GIMPYISASIVIQLLATVSPALAELKKEGAAGQRKISKYTRYATVVFATIQAVAISTGLPNMLSGLVPNVGFSFYFTSVV
SLVTGTMFLMWLGEQITERGIGNGISILVFGGIVAGLPSAILQTIEQARQGQMHPLVLLLIAAIVFAVTYFVVFVERGQR
RIRVEYAKRQQGRQILGGHSTHLPLKVNMANVMPAIFASSIILFPATLTQWFGQNDKFEWLNNLSMLLNPGQPLYLLVYA
VAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKVMTRLTLIGGLYVTFVCLVPYIMTSAWDVKFYFG
GTSLLIVVVVIMDFIVQVQSHLMSSQYESALKKANLKGFGQ
>Mature_440_residues
AKQPGYQARSTNSGKGELKSRLLFVLGALIVYRIGSFIPVPGIDAAVLAQLVEQQKGTIIDMFNMFSGGALSRASILALG
IMPYISASIVIQLLATVSPALAELKKEGAAGQRKISKYTRYATVVFATIQAVAISTGLPNMLSGLVPNVGFSFYFTSVVS
LVTGTMFLMWLGEQITERGIGNGISILVFGGIVAGLPSAILQTIEQARQGQMHPLVLLLIAAIVFAVTYFVVFVERGQRR
IRVEYAKRQQGRQILGGHSTHLPLKVNMANVMPAIFASSIILFPATLTQWFGQNDKFEWLNNLSMLLNPGQPLYLLVYAV
AIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQTSRYIDKVMTRLTLIGGLYVTFVCLVPYIMTSAWDVKFYFGG
TSLLIVVVVIMDFIVQVQSHLMSSQYESALKKANLKGFGQ

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=74.7178329571106, Blast_Score=623, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_HAEIN (P43804)

Other databases:

- EMBL:   L42023
- PIR:   G64094
- RefSeq:   NP_438957.1
- ProteinModelPortal:   P43804
- GeneID:   949574
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0798
- TIGR:   HI_0798
- HOGENOM:   HBG565931
- OMA:   IQTYVIS
- ProtClustDB:   PRK09204
- BioCyc:   HINF71421:HI_0798-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 48291; Mature: 48160

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00755 SECY_1; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcf4f8c0)-; HASH(0xbd92078)-; HASH(0xd72f990)-; HASH(0xb04e0d4)-; HASH(0xd68b468)-; HASH(0xc62ffb4)-; HASH(0xb7184d8)-; HASH(0xb4778d4)-; HASH(0xd5d968c)-; HASH(0xd3953b8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
AKQPGYQARSTNSGKGELKSRLLFVLGALIVYRIGSFIPVPGIDAAVLAQLVEQQKGTI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCE
IDMFNMFSGGALSRASILALGIMPYISASIVIQLLATVSPALAELKKEGAAGQRKISKYT
EHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RYATVVFATIQAVAISTGLPNMLSGLVPNVGFSFYFTSVVSLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISILVFGGIVAGLPSAILQTIEQARQGQMHPLVLLLIAAIVFAVTYFVVFVERGQR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
RIRVEYAKRQQGRQILGGHSTHLPLKVNMANVMPAIFASSIILFPATLTQWFGQNDKFEW
HHHHHHHHHHCCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LNNLSMLLNPGQPLYLLVYAVAIIFFSFFYTAMQYNPRDTADNLKKSGAFIPGIRPGEQT
HHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHH
SRYIDKVMTRLTLIGGLYVTFVCLVPYIMTSAWDVKFYFGGTSLLIVVVVIMDFIVQVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
HLMSSQYESALKKANLKGFGQ
HHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800