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The map label for this gene is anmK

Identifier: 16272694

GI number: 16272694

Start: 817101

End: 818249

Strand: Direct

Name: anmK

Synonym: HI0753

Alternate gene names: 16272694

Gene position: 817101-818249 (Clockwise)

Preceding gene: 16272693

Following gene: 16272695

Centisome position: 44.65

GC content: 39.25

Gene sequence:

>1149_bases
ATGATTAATATGAAACCTCAATATTATCTTGGTATGATGTCGGGTACTAGCTTAGATGGCGTGGATATTGTGTTGGTTGA
TTTTTCTCAAGATCCTCAACTTATCCTATCTGATTTTTTTCCTATGCCAGAAGATTTGCGTGAGAAATTAACCACACTTA
TTCAAGTAGGTGAAACAACTCTACAAAATTTAGGCGAACTGGATCATAAACTTGCCTTGCTATACAGTGATTGTGTCAAT
GCTTTTCTGCAGAAAAATACTTTTTTGCCAAATCAAATTCAGGCTATTGGTTGCCACGGGCAAACGGTATGGCATTCTCC
AAATTCACAATTTCCCTTTACAATGCAATTAGGCGATATGAATTTACTTGCCGCTAAAACAGGCATTTCGGTTATTGGGG
ATTTTCGCCGTAAGGATATGGCTTGGGGTGGACAAGGTGCGCCTCTTGTGCCTGCGTTTCACGAGGCGGTATTTTCAAAT
TCTAATTTTGCTACAGCTGTTTTAAATATTGGCGGGATTAGTAATGTGTCTATTTTGTTTCCAAATCAAGCTGTCATCGG
CTTTGATACAGGTCCAGGTAATACATTATTAGATCAATGGATCGAAAAACATCAAGGGCTTCGTTATGATGAAAATGGCG
AGTGGGCAGCAAAAGGCAACGTGAATAAAGTTCTGCTTGATGAATTACTCAATGAACCTTTCTTTTCTTTACCTGCACCC
AAGAGTACTGGGAGAGAATTATTTAACCTTGTTTGGTTAAATCACAAAATAGCAAAAATAAGGGAAAAATTGACCGCACT
TTCAGTTGAAATGTCTTTTCGCCCAGAGGATGTGCAAGCGACGCTTGTTGAATTGACGGTAACAAGCATTGTTAATGCAC
TAAATCAGCTCCAAACAGATTTACCAAAACGTTTACTAGTATGTGGCGGTGGTGCCAAGAATAGCTTAATTATGCGTGGA
TTGCATGATAATTTACTCGATTGGCAGGTCAGCACAACGACAGAGCAAGGTTTTGATATTGATTATGTCGAAGCCGCTGC
TTTTGCTTGGTTAGCTTATTGTCGAATCAACAATTTACCTGCAAATCTACCAAGTGTAACTGGGGCAAAAAGTGCGGTTA
GTTTGGGGGCTATTTTTCCTAAAGACTAA

Upstream 100 bases:

>100_bases
TTCAATTTTATGTAATTGTTTTTAGTTGTGTTTTTGTTTGATGATTTAATTATTTTTATTGTTAAGTTAGCGATATAATC
ATCAAAATAGAAATATAGAA

Downstream 100 bases:

>100_bases
GGTCAAAATATGAATGACATTATATTAAAAAGTTTATCCACATTAATTACGGAACAAAGAAATCCGAATTCAGTTGATAT
TGATCGTCAAAGTACATTAG

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MINMKPQYYLGMMSGTSLDGVDIVLVDFSQDPQLILSDFFPMPEDLREKLTTLIQVGETTLQNLGELDHKLALLYSDCVN
AFLQKNTFLPNQIQAIGCHGQTVWHSPNSQFPFTMQLGDMNLLAAKTGISVIGDFRRKDMAWGGQGAPLVPAFHEAVFSN
SNFATAVLNIGGISNVSILFPNQAVIGFDTGPGNTLLDQWIEKHQGLRYDENGEWAAKGNVNKVLLDELLNEPFFSLPAP
KSTGRELFNLVWLNHKIAKIREKLTALSVEMSFRPEDVQATLVELTVTSIVNALNQLQTDLPKRLLVCGGGAKNSLIMRG
LHDNLLDWQVSTTTEQGFDIDYVEAAAFAWLAYCRINNLPANLPSVTGAKSAVSLGAIFPKD

Sequences:

>Translated_382_residues
MINMKPQYYLGMMSGTSLDGVDIVLVDFSQDPQLILSDFFPMPEDLREKLTTLIQVGETTLQNLGELDHKLALLYSDCVN
AFLQKNTFLPNQIQAIGCHGQTVWHSPNSQFPFTMQLGDMNLLAAKTGISVIGDFRRKDMAWGGQGAPLVPAFHEAVFSN
SNFATAVLNIGGISNVSILFPNQAVIGFDTGPGNTLLDQWIEKHQGLRYDENGEWAAKGNVNKVLLDELLNEPFFSLPAP
KSTGRELFNLVWLNHKIAKIREKLTALSVEMSFRPEDVQATLVELTVTSIVNALNQLQTDLPKRLLVCGGGAKNSLIMRG
LHDNLLDWQVSTTTEQGFDIDYVEAAAFAWLAYCRINNLPANLPSVTGAKSAVSLGAIFPKD
>Mature_382_residues
MINMKPQYYLGMMSGTSLDGVDIVLVDFSQDPQLILSDFFPMPEDLREKLTTLIQVGETTLQNLGELDHKLALLYSDCVN
AFLQKNTFLPNQIQAIGCHGQTVWHSPNSQFPFTMQLGDMNLLAAKTGISVIGDFRRKDMAWGGQGAPLVPAFHEAVFSN
SNFATAVLNIGGISNVSILFPNQAVIGFDTGPGNTLLDQWIEKHQGLRYDENGEWAAKGNVNKVLLDELLNEPFFSLPAP
KSTGRELFNLVWLNHKIAKIREKLTALSVEMSFRPEDVQATLVELTVTSIVNALNQLQTDLPKRLLVCGGGAKNSLIMRG
LHDNLLDWQVSTTTEQGFDIDYVEAAAFAWLAYCRINNLPANLPSVTGAKSAVSLGAIFPKD

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=380, Percent_Identity=47.3684210526316, Blast_Score=335, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_HAEIN (P44861)

Other databases:

- EMBL:   L42023
- PIR:   B64158
- RefSeq:   NP_438912.1
- ProteinModelPortal:   P44861
- SMR:   P44861
- GeneID:   949467
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0753
- NMPDR:   fig|71421.1.peg.721
- TIGR:   HI_0753
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   HINF71421:HI_0753-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 42027; Mature: 42027

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINMKPQYYLGMMSGTSLDGVDIVLVDFSQDPQLILSDFFPMPEDLREKLTTLIQVGETT
CCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LQNLGELDHKLALLYSDCVNAFLQKNTFLPNQIQAIGCHGQTVWHSPNSQFPFTMQLGDM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEECCCCCCCCEEEEECCC
NLLAAKTGISVIGDFRRKDMAWGGQGAPLVPAFHEAVFSNSNFATAVLNIGGISNVSILF
EEEHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEEE
PNQAVIGFDTGPGNTLLDQWIEKHQGLRYDENGEWAAKGNVNKVLLDELLNEPFFSLPAP
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCCC
KSTGRELFNLVWLNHKIAKIREKLTALSVEMSFRPEDVQATLVELTVTSIVNALNQLQTD
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LPKRLLVCGGGAKNSLIMRGLHDNLLDWQVSTTTEQGFDIDYVEAAAFAWLAYCRINNLP
CCCEEEEECCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ANLPSVTGAKSAVSLGAIFPKD
CCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MINMKPQYYLGMMSGTSLDGVDIVLVDFSQDPQLILSDFFPMPEDLREKLTTLIQVGETT
CCCCCCCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LQNLGELDHKLALLYSDCVNAFLQKNTFLPNQIQAIGCHGQTVWHSPNSQFPFTMQLGDM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEECCCCCCCCEEEEECCC
NLLAAKTGISVIGDFRRKDMAWGGQGAPLVPAFHEAVFSNSNFATAVLNIGGISNVSILF
EEEHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEEE
PNQAVIGFDTGPGNTLLDQWIEKHQGLRYDENGEWAAKGNVNKVLLDELLNEPFFSLPAP
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCCC
KSTGRELFNLVWLNHKIAKIREKLTALSVEMSFRPEDVQATLVELTVTSIVNALNQLQTD
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LPKRLLVCGGGAKNSLIMRGLHDNLLDWQVSTTTEQGFDIDYVEAAAFAWLAYCRINNLP
CCCEEEEECCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ANLPSVTGAKSAVSLGAIFPKD
CCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800