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The map label for this gene is trkH

Identifier: 16272663

GI number: 16272663

Start: 769389

End: 770852

Strand: Direct

Name: trkH

Synonym: HI0723

Alternate gene names: 16272663

Gene position: 769389-770852 (Clockwise)

Preceding gene: 30995396

Following gene: 16272664

Centisome position: 42.04

GC content: 36.34

Gene sequence:

>1464_bases
GTGCGTATTTTATCGATTATCCGAATTATTGGTATTCTTGTGATGTGTTTTTCAGGTACGATGCTAGTTCCTGCATTTGT
TGCTCTGATTTATGGTGATGGGGGCGGCAAGGCATTTATGCAGGCTTTTATGTTGAGCTTGATTGCAGGTACATTACTTT
GGTGGCCATGCCATCACCATAAACAAGAATTACGATCCCGTGATGGTTTTTTGATTGTTGTGGCTTTTTGGTTAGTTTTA
GGAAGCTTGGCAACATTGCCTCTTTTATTGTTCGATTCACCACATTTAACTATTGCTTCAGCCGTATTTGAAGCATTTTC
TGGCTTAACTACTACTGGTGCAACGGTAATGACGGGGCTGGATAATTTACCTAAATCTATTTTGTTTTATCGTCAGTTTT
TACAATGGTTAGGTGGTATGGGGATTATCGTATTGGCTGTGGCGATAATTCCGCTGTTGGGAATTGGTGGGACACAATTA
TATCGAGCAGAATCTTCAGGCCCTCTTAAAGATCAAAAATCTTTGCCTAAAATTTCAGAAGTGGCGAAAGCTCTATGGAT
TATTTATGCTTCATTAACTGTTCTTTGTGCCATTGCATATTGGCTATCAGGAATGAATCTTTTTGATGCCATTGGGCATA
GTTTTTCAACAATTTCAAATGGCGGATTTTCAACGCACGATGCAAGTATTGGCTATTTTAATCAAGCTTCCATTTATTGG
GTTACAACAATTTTTATGCTGATTGGTGGTGTTAATTTTAGTTTACATATTTCCGCTTTTCTTGCACTAGGTAAAAGAAA
TATTTGGCGAAATTATTGGAAAGATCCCGAATTTCGTTTTTTTCTAACGATGCAAATTATTTTTATTGGTATTGTATCTC
TATCTTTATATGGTTATGGTTTAGTTTCAGATATAAACGAGGCAGTAACAAAAGGTGCATTACAATTAACATCAATGTCA
ATGACTGCTGGTTATACGATTTTTGATATTGATAATCTTCCGCCTTTTATTGGGCTTTTACTGGTAATTTCTGCAGTAAT
TGGTGGTTGTGGTGGTTCAACAACTGGGGGATTAAAAGCGATACGGACACTTATATTGTGGAAACAAATCGATCGAGAAC
TGCATAGTTTAATCCATCCAAATTTAGTACAACCAATTCGAATAGGTAAAAATCGTCTAGCACCAAGAATGATAGAAAGT
ATTTGGGCATTTTTCATTATTTTTATACTGGTTTATTGGGGGTGTGTTTTTGCTGTTATTCTTTGTGGAATGAATACTTT
TGATGCGATGGGAGCCGTATTCGCCACATTAACGAATGCAGGACCGGGACTTGGTTTTATTCACGAAAGTTTTATTGGTG
TTCCAGAAAGTGCTAAATTAGTCTTTAGTTTTGCTATGATCTGTGGACGTTTAGAAATGTTTTCATTAATCGTGCTGTTT
ATTCCAAGCTATTGGAAAAAATAA

Upstream 100 bases:

>100_bases
TAGGTATTAGTGAAAAAACAATAGAGGCGTTTTCTTCAGAATTAACGGAAAAGTCTTCAGGTAGATTAGTTATTCAACTT
TTAGAGATAGGCGAATAGTT

Downstream 100 bases:

>100_bases
TAATTGAAAAATTATTGCATTTTTAACCGCACTTTTTAATAAAATGTTTATATTTCCATCAAAAGATCATTTTTTTAAAT
ATTTTTACAAAAAGTACTTG

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLIAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK

Sequences:

>Translated_487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLIAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK
>Mature_487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLIAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family

Homologues:

Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=52.5667351129363, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=36.7768595041322, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRKH_HAEIN (P44843)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_438881.1
- GeneID:   949570
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0723
- NMPDR:   fig|71421.1.peg.691
- TIGR:   HI_0723
- HOGENOM:   HBG732766
- OMA:   HPRAIYT
- ProtClustDB:   CLSK789785
- BioCyc:   HINF71421:HI_0723-MONOMER
- InterPro:   IPR003445
- InterPro:   IPR004772
- TIGRFAMs:   TIGR00933

Pfam domain/function: PF02386 TrkH

EC number: NA

Molecular weight: Translated: 53469; Mature: 53469

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd32d0ac)-; HASH(0xd1fc104)-; HASH(0xd261f04)-; HASH(0xcdd7e78)-; HASH(0xbec58a4)-; HASH(0xd45f3b4)-; HASH(0xd28e228)-; HASH(0xd5c86d8)-; HASH(0xc489a60)-; HASH(0xc1759a4)-; HASH(0xd17fa6c)-; HASH(0xd5e0cb4)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLIAGTLLWWPCHHH
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
KQELRSRDGFLIVVAFWLVLGSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGL
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQLYRAESSGPLKDQKSLPKISE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCHHHH
VAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHH
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCH
LVSDINEAVTKGALQLTSMSMTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
IRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIESIWAFFIIFILVYWGCVFAVI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPSYWKK
HHHHHCH
>Mature Secondary Structure
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLIAGTLLWWPCHHH
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
KQELRSRDGFLIVVAFWLVLGSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGL
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQLYRAESSGPLKDQKSLPKISE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCHHHH
VAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHH
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCH
LVSDINEAVTKGALQLTSMSMTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
IRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIESIWAFFIIFILVYWGCVFAVI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPSYWKK
HHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800