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The map label for this gene is lppB

Identifier: 16272646

GI number: 16272646

Start: 749811

End: 751028

Strand: Direct

Name: lppB

Synonym: HI0706

Alternate gene names: 16272646

Gene position: 749811-751028 (Clockwise)

Preceding gene: 16272645

Following gene: 16272647

Centisome position: 40.97

GC content: 40.48

Gene sequence:

>1218_bases
ATGAAAAAATCGTTTCTCTTACTCCCTTTGAGTCTTGTTGTATTATCGGCTTGTACCTCTAATTTTCCTGCACCTATTTC
TGATGCAGATGGAAATTTTTCCCCTAGTGTAATACAATCTGTAAATGGCAGTAATGTAGGTGGTGCTTGGCAACCTGAAA
TTCAAAAAAATTCATTACCTACAACGGGAAATATGGTCACGCCACAACAAAATTTTCAACCGATTAATCAACAACCAACA
ATGCCAACAGCACCTGCACAACCTGCATTTCAACCCTCTCCGAAAACCGTAGTTAGTGCACCGACAGTACAAACAAAAAC
AGTTACCAAAACAGTCGCTGATTGTGTAGATGGACAGCATATTAATATCCCACGTAATCCAAATACCAATGCGCCAGATT
ACAGCAAAATCTCAAAAGGCTCTTACAAAGGCAATACCTATAAAGTAAACAAAGGCGATACAATGTTCTTAATCGCTTAC
TTGGCGGGGATTGATGTAAAAGAATTGGCGGCGTTGAATAACCTATCCGAACCTTATAATTTAAGTTTAGGGCAAGTTTT
AAAGATTTCTAATTGTGACATAAAAACGGTTACTACAACGGTTTCTGTAAAACAACCTGCAGTCACAGCATCAACAGCAA
CGCCAGTTAAACCAGCAGTCACTTATACTCCGGGCGCAAACGGTACTCAAATAGGATCTGACGGTACTATTATTGGCCCA
ATTAAATCAGAGGCTGGCACATCGCCTAGTGTACCTGTGGCAACTTCATCAACACAGGTTACATCATCTGTAAATAATGC
GAATAGCACACCAATTAATTCCAATGTCGTTGCGCCAATCGCCTCAAATGTTGTGTGGCAATGGCCGACTTCAGGTAATA
TCATCCAAGGTTTCTCAAGCACAGATGGCGGTAACAAAGGAATTGATATTAGTGGTTCACGAGGACAAGCTGTAAAAGCG
GCTGCAGCAGGGCGAATAGTGTATGCAGGCAATGCTTTACGTGGTTACGGTAATTTAATTATCATCAAACATAATGATGA
TTTTTTAAGTGCCTATGCGCATAACGACAAAATTCTTGTCGCCGATCAACAAGAAGTCAAAGCAGGTCAAGACATCGCAA
AAATGGGTAGCTCTGGTACAAATACCGTGAAACTCCACTTTGAAATTCGCTATAAAGGTAAATCAGTGGATCCAGTACGT
TACCTACCAAGACATTAA

Upstream 100 bases:

>100_bases
AAGGCACTGGTGCCGTTGCTGGCGGTAGTTTTATGCCAGAAATTCAAAAAAATACGATACCAACACAAATGAAATAATAA
CGGAACAATAAGGAATAACT

Downstream 100 bases:

>100_bases
TCTTCCTGTAAAAAGTGCGGTAAAAAATCTCAACAAATTTTTACCGCACTTTTATCTGGCTTTTTCCCCTTTCGGCACCT
AAAATAGCCGCCACAAAACC

Product: lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKKSFLLLPLSLVVLSACTSNFPAPISDADGNFSPSVIQSVNGSNVGGAWQPEIQKNSLPTTGNMVTPQQNFQPINQQPT
MPTAPAQPAFQPSPKTVVSAPTVQTKTVTKTVADCVDGQHINIPRNPNTNAPDYSKISKGSYKGNTYKVNKGDTMFLIAY
LAGIDVKELAALNNLSEPYNLSLGQVLKISNCDIKTVTTTVSVKQPAVTASTATPVKPAVTYTPGANGTQIGSDGTIIGP
IKSEAGTSPSVPVATSSTQVTSSVNNANSTPINSNVVAPIASNVVWQWPTSGNIIQGFSSTDGGNKGIDISGSRGQAVKA
AAAGRIVYAGNALRGYGNLIIIKHNDDFLSAYAHNDKILVADQQEVKAGQDIAKMGSSGTNTVKLHFEIRYKGKSVDPVR
YLPRH

Sequences:

>Translated_405_residues
MKKSFLLLPLSLVVLSACTSNFPAPISDADGNFSPSVIQSVNGSNVGGAWQPEIQKNSLPTTGNMVTPQQNFQPINQQPT
MPTAPAQPAFQPSPKTVVSAPTVQTKTVTKTVADCVDGQHINIPRNPNTNAPDYSKISKGSYKGNTYKVNKGDTMFLIAY
LAGIDVKELAALNNLSEPYNLSLGQVLKISNCDIKTVTTTVSVKQPAVTASTATPVKPAVTYTPGANGTQIGSDGTIIGP
IKSEAGTSPSVPVATSSTQVTSSVNNANSTPINSNVVAPIASNVVWQWPTSGNIIQGFSSTDGGNKGIDISGSRGQAVKA
AAAGRIVYAGNALRGYGNLIIIKHNDDFLSAYAHNDKILVADQQEVKAGQDIAKMGSSGTNTVKLHFEIRYKGKSVDPVR
YLPRH
>Mature_405_residues
MKKSFLLLPLSLVVLSACTSNFPAPISDADGNFSPSVIQSVNGSNVGGAWQPEIQKNSLPTTGNMVTPQQNFQPINQQPT
MPTAPAQPAFQPSPKTVVSAPTVQTKTVTKTVADCVDGQHINIPRNPNTNAPDYSKISKGSYKGNTYKVNKGDTMFLIAY
LAGIDVKELAALNNLSEPYNLSLGQVLKISNCDIKTVTTTVSVKQPAVTASTATPVKPAVTYTPGANGTQIGSDGTIIGP
IKSEAGTSPSVPVATSSTQVTSSVNNANSTPINSNVVAPIASNVVWQWPTSGNIIQGFSSTDGGNKGIDISGSRGQAVKA
AAAGRIVYAGNALRGYGNLIIIKHNDDFLSAYAHNDKILVADQQEVKAGQDIAKMGSSGTNTVKLHFEIRYKGKSVDPVR
YLPRH

Specific function: May be a virulence determinant

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat

Homologues:

Organism=Escherichia coli, GI1789099, Length=283, Percent_Identity=46.643109540636, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87082174, Length=264, Percent_Identity=39.7727272727273, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI87082297, Length=121, Percent_Identity=38.0165289256198, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPPB_HAEIN (P44833)

Other databases:

- EMBL:   L42023
- PIR:   F64087
- RefSeq:   NP_438864.1
- ProteinModelPortal:   P44833
- SMR:   P44833
- GeneID:   949731
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0706
- NMPDR:   fig|71421.1.peg.674
- TIGR:   HI_0706
- HOGENOM:   HBG754735
- OMA:   NIPEPYS
- ProtClustDB:   CLSK892381
- BioCyc:   HINF71421:HI_0706-MONOMER
- GO:   GO:0009405
- GO:   GO:0006508
- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482
- PANTHER:   PTHR21666:SF7
- SMART:   SM00257

Pfam domain/function: PF01476 LysM; PF01551 Peptidase_M23; SSF51261 Dup_hybrid_motif

EC number: NA

Molecular weight: Translated: 42505; Mature: 42505

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSFLLLPLSLVVLSACTSNFPAPISDADGNFSPSVIQSVNGSNVGGAWQPEIQKNSLP
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
TTGNMVTPQQNFQPINQQPTMPTAPAQPAFQPSPKTVVSAPTVQTKTVTKTVADCVDGQH
CCCCEECCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCE
INIPRNPNTNAPDYSKISKGSYKGNTYKVNKGDTMFLIAYLAGIDVKELAALNNLSEPYN
EECCCCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEEHHCCCHHHHHHHHCCCCCCC
LSLGQVLKISNCDIKTVTTTVSVKQPAVTASTATPVKPAVTYTPGANGTQIGSDGTIIGP
CCCCCEEEECCCCEEEEEEEEEECCCCEECCCCCCCCCCEEECCCCCCCEECCCCCEEEC
IKSEAGTSPSVPVATSSTQVTSSVNNANSTPINSNVVAPIASNVVWQWPTSGNIIQGFSS
CCCCCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEECCCC
TDGGNKGIDISGSRGQAVKAAAAGRIVYAGNALRGYGNLIIIKHNDDFLSAYAHNDKILV
CCCCCCCEEECCCCCCEEEHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCEEEE
ADQQEVKAGQDIAKMGSSGTNTVKLHFEIRYKGKSVDPVRYLPRH
ECHHHHHCCHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHCCCCC
>Mature Secondary Structure
MKKSFLLLPLSLVVLSACTSNFPAPISDADGNFSPSVIQSVNGSNVGGAWQPEIQKNSLP
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
TTGNMVTPQQNFQPINQQPTMPTAPAQPAFQPSPKTVVSAPTVQTKTVTKTVADCVDGQH
CCCCEECCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCE
INIPRNPNTNAPDYSKISKGSYKGNTYKVNKGDTMFLIAYLAGIDVKELAALNNLSEPYN
EECCCCCCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEEHHCCCHHHHHHHHCCCCCCC
LSLGQVLKISNCDIKTVTTTVSVKQPAVTASTATPVKPAVTYTPGANGTQIGSDGTIIGP
CCCCCEEEECCCCEEEEEEEEEECCCCEECCCCCCCCCCEEECCCCCCCEECCCCCEEEC
IKSEAGTSPSVPVATSSTQVTSSVNNANSTPINSNVVAPIASNVVWQWPTSGNIIQGFSS
CCCCCCCCCCCEEECCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEECCCC
TDGGNKGIDISGSRGQAVKAAAAGRIVYAGNALRGYGNLIIIKHNDDFLSAYAHNDKILV
CCCCCCCEEECCCCCCEEEHHHCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCEEEE
ADQQEVKAGQDIAKMGSSGTNTVKLHFEIRYKGKSVDPVRYLPRH
ECHHHHHCCHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800