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The map label for this gene is glpQ

Identifier: 16272631

GI number: 16272631

Start: 732946

End: 734040

Strand: Direct

Name: glpQ

Synonym: HI0689

Alternate gene names: 16272631

Gene position: 732946-734040 (Clockwise)

Preceding gene: 16272630

Following gene: 16272632

Centisome position: 40.05

GC content: 35.71

Gene sequence:

>1095_bases
ATGAAACTTAAAACTTTAGCCCTTTCTTTATTAGCAGCTGGCGTACTAGCAGGTTGTAGCAGCCATTCATCAAATATGGC
GAATACCCAAATGAAATCAGACAAAATCATTATTGCTCACCGTGGTGCTAGCGGTTATTTACCAGAGCATACGTTAGAAT
CTAAAGCACTTGCGTTTGCACAACACTCAGATTATTTAGAGCAAGATTTAGCAATGACTAAGGATGGTCGTTTAGTGGTT
ATTCACGATCACTTTTTAGATGGCTTGACTGATGTTGCGAAAAAATTCCCATATCGTCACCGTAAAGATGGTCGTTACTA
TGTCATCGACTTTACCTTAAAAGAAATTCAAAGTTTAGAAATGACAGAAAACTTTGAAACCAAAGATGGCAAACAAGCAC
AAGTTTATCCTAATCGTTTCCCACTTTGGAAATCACATTTTAGAATTCATACCTTTGAAGATGAAATTGAATTTATCCAA
GGCTTAGAAAAATCCACTGGCAAAAAAGTAGGGATTTATCCAGAAATCAAAGCACCTTGGTTCCACCATCAAAATGGTAA
AGATATTGCTACAGAAACGCTCAAAGTGTTAAAAAAATATGGCTATGATAAGAAAACCGATATGGTTTACTTGCAAACTT
TCGATTTTAATGAATTAAAACGTATCAAAACGGAATTACTTCCACAAATGGGTATGGATTTGAAATTAGTTCAATTAATT
GCTTATACAGATTGGAAAGAAACACAAGAAAAAGACCCAAAGGGTTATTGGGTAAACTATAATTACGATTGGATGTTTAA
ACCTGGTGCAATGGCAGAAGTGGTTAAATATGCCGATGGTGTTGGTCCAGGTTGGTATATGTTAGTTAATAAAGAAGAAT
CCAAACCTGATAATATTGTGTACACTCCGTTGGTAAAAGAACTTGCACAATATAATGTGGAAGTGCATCCTTACACCGTG
CGTAAAGATGCACTGCCCGAGTTTTTCACAGACGTAAATCAAATGTATGATGCCTTATTGAATAAATCAGGGGCAACAGG
TGTATTTACTGATTTCCCAGATACTGGCGTGGAATTCTTAAAAGGAATAAAATAA

Upstream 100 bases:

>100_bases
CAAGTGCTGAAACATCTTTAGAAACTATTAAAATTATTCACGGAATAATTAATTCTGTTAAAATAGGTAATGATCCTAAC
AATATATAAGGAGAATAAGT

Downstream 100 bases:

>100_bases
TATCCCTCACAACCGTGGGTAAACATACCCACGGTTAACTAGGTTTCTATATCGTAGAAACTAAAAATCTACTCTAACAG
AGTAACATCATAATCAATCT

Product: glycerophosphodiester phosphodiesterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase; Immunoglobulin D-binding protein; IgD-binding protein; Surface-exposed lipoprotein D; Protein D

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKLKTLALSLLAAGVLAGCSSHSSNMANTQMKSDKIIIAHRGASGYLPEHTLESKALAFAQHSDYLEQDLAMTKDGRLVV
IHDHFLDGLTDVAKKFPYRHRKDGRYYVIDFTLKEIQSLEMTENFETKDGKQAQVYPNRFPLWKSHFRIHTFEDEIEFIQ
GLEKSTGKKVGIYPEIKAPWFHHQNGKDIATETLKVLKKYGYDKKTDMVYLQTFDFNELKRIKTELLPQMGMDLKLVQLI
AYTDWKETQEKDPKGYWVNYNYDWMFKPGAMAEVVKYADGVGPGWYMLVNKEESKPDNIVYTPLVKELAQYNVEVHPYTV
RKDALPEFFTDVNQMYDALLNKSGATGVFTDFPDTGVEFLKGIK

Sequences:

>Translated_364_residues
MKLKTLALSLLAAGVLAGCSSHSSNMANTQMKSDKIIIAHRGASGYLPEHTLESKALAFAQHSDYLEQDLAMTKDGRLVV
IHDHFLDGLTDVAKKFPYRHRKDGRYYVIDFTLKEIQSLEMTENFETKDGKQAQVYPNRFPLWKSHFRIHTFEDEIEFIQ
GLEKSTGKKVGIYPEIKAPWFHHQNGKDIATETLKVLKKYGYDKKTDMVYLQTFDFNELKRIKTELLPQMGMDLKLVQLI
AYTDWKETQEKDPKGYWVNYNYDWMFKPGAMAEVVKYADGVGPGWYMLVNKEESKPDNIVYTPLVKELAQYNVEVHPYTV
RKDALPEFFTDVNQMYDALLNKSGATGVFTDFPDTGVEFLKGIK
>Mature_364_residues
MKLKTLALSLLAAGVLAGCSSHSSNMANTQMKSDKIIIAHRGASGYLPEHTLESKALAFAQHSDYLEQDLAMTKDGRLVV
IHDHFLDGLTDVAKKFPYRHRKDGRYYVIDFTLKEIQSLEMTENFETKDGKQAQVYPNRFPLWKSHFRIHTFEDEIEFIQ
GLEKSTGKKVGIYPEIKAPWFHHQNGKDIATETLKVLKKYGYDKKTDMVYLQTFDFNELKRIKTELLPQMGMDLKLVQLI
AYTDWKETQEKDPKGYWVNYNYDWMFKPGAMAEVVKYADGVGPGWYMLVNKEESKPDNIVYTPLVKELAQYNVEVHPYTV
RKDALPEFFTDVNQMYDALLNKSGATGVFTDFPDTGVEFLKGIK

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Has a specific affinity for human immunoglobulin D myeloma protein

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family

Homologues:

Organism=Escherichia coli, GI1788572, Length=360, Percent_Identity=63.3333333333333, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPQ_HAEIN (Q06282)

Other databases:

- EMBL:   L42023
- EMBL:   M37487
- EMBL:   L12445
- EMBL:   Z35656
- EMBL:   Z35657
- EMBL:   Z35658
- EMBL:   Z35659
- EMBL:   Z35660
- EMBL:   Z35661
- PIR:   G64086
- PIR:   S59931
- PIR:   S59932
- PIR:   S59933
- PIR:   S59934
- PIR:   S59936
- RefSeq:   NP_438849.1
- ProteinModelPortal:   Q06282
- SMR:   Q06282
- GeneID:   949981
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0689
- NMPDR:   fig|71421.1.peg.659
- TIGR:   HI_0689
- HOGENOM:   HBG725117
- OMA:   YSYDWMF
- ProtClustDB:   PRK11143
- BioCyc:   HINF71421:HI_0689-MONOMER
- BRENDA:   3.1.4.46
- InterPro:   IPR004129
- InterPro:   IPR017946
- Gene3D:   G3DSA:3.20.20.190
- PANTHER:   PTHR23344

Pfam domain/function: PF03009 GDPD; SSF51695 PLC-like_Pdiesterase_TIM-brl

EC number: =3.1.4.46

Molecular weight: Translated: 41902; Mature: 41902

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTLALSLLAAGVLAGCSSHSSNMANTQMKSDKIIIAHRGASGYLPEHTLESKALAFA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
QHSDYLEQDLAMTKDGRLVVIHDHFLDGLTDVAKKFPYRHRKDGRYYVIDFTLKEIQSLE
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHH
MTENFETKDGKQAQVYPNRFPLWKSHFRIHTFEDEIEFIQGLEKSTGKKVGIYPEIKAPW
HCCCCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEECCCCCCCCCC
FHHQNGKDIATETLKVLKKYGYDKKTDMVYLQTFDFNELKRIKTELLPQMGMDLKLVQLI
EECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH
AYTDWKETQEKDPKGYWVNYNYDWMFKPGAMAEVVKYADGVGPGWYMLVNKEESKPDNIV
HHCCCHHHHCCCCCCEEEEECEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEE
YTPLVKELAQYNVEVHPYTVRKDALPEFFTDVNQMYDALLNKSGATGVFTDFPDTGVEFL
ECHHHHHHHHCCCEECCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHH
KGIK
HCCC
>Mature Secondary Structure
MKLKTLALSLLAAGVLAGCSSHSSNMANTQMKSDKIIIAHRGASGYLPEHTLESKALAFA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
QHSDYLEQDLAMTKDGRLVVIHDHFLDGLTDVAKKFPYRHRKDGRYYVIDFTLKEIQSLE
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHH
MTENFETKDGKQAQVYPNRFPLWKSHFRIHTFEDEIEFIQGLEKSTGKKVGIYPEIKAPW
HCCCCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEECCCCCCCCCC
FHHQNGKDIATETLKVLKKYGYDKKTDMVYLQTFDFNELKRIKTELLPQMGMDLKLVQLI
EECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH
AYTDWKETQEKDPKGYWVNYNYDWMFKPGAMAEVVKYADGVGPGWYMLVNKEESKPDNIV
HHCCCHHHHCCCCCCEEEEECEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEE
YTPLVKELAQYNVEVHPYTVRKDALPEFFTDVNQMYDALLNKSGATGVFTDFPDTGVEFL
ECHHHHHHHHCCCEECCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHH
KGIK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 1987023; 8104899; 7822043; 1548059