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The map label for this gene is glpX

Identifier: 16272609

GI number: 16272609

Start: 712489

End: 713490

Strand: Reverse

Name: glpX

Synonym: HI0667

Alternate gene names: 16272609

Gene position: 713490-712489 (Counterclockwise)

Preceding gene: 16272613

Following gene: 16272608

Centisome position: 38.99

GC content: 41.72

Gene sequence:

>1002_bases
ATGAATCGAGCATTAGCCATTGAATTTTCACGAGTAACAGAAGCCGCCGCTCTAGCAGCTTACACGTGGCTTGGTCGAGG
AGATAAAAATGCGGCAGACGATGCAGCGGTAAAAGCGATGCGTTATATGCTGAATTTAATTCATATGGACGCTGAAATCG
TTATAGGAGAGGGCGAAATTGATGAAGCCCCAATGCTTTATGTTGGCGAAAAAGTCGGTTCTGGCTTAGGGGAATTAGTT
TCTATCGCAGTAGATCCTATTGATGGTACACATATGACCGCAATGGGGCAATCTAATGCCATTTCTGTCTTGGCTGCAGG
TGGCAAAAATACCTTTTTAAAAGCACCTGATATGTATATGGAAAAATTAGTGGTGGGTTCAAATGTAAAAGGCATCATTG
ATTTAAATTTACCACTGGAACAAAATCTTCGCCGCATCGCATCTAAGCTAGGAAAATCCCTTTCTGACCTTACCGTAATG
GTATTAGCAAAACCACGTCACGATGCTGTAATTAAACAAATACATAACTTGGGCGCGAAAGTATTGGCAATTCCTGATGG
CGATGTGGCAGGTTCTGTGCTTTGCTGCTTACCTGATGCTGAAGTCGATCTTCTTTATGGAATTGGTGGTGCGCCAGAAG
GCGTGGCAGCTGCTGCAGCCATTCGAGCATTAGGTGGTGATATGCAAGCTCGTTTAATCCCACGCAATGAAGTAAAAAGC
GACACCGAAGAAAATAAAAAAATTGCAGCTAATGAGATTCAACGCTGTGCAGCACTGGGCGTAAAAGTGAATGAAGTGTT
AAAACTTGAAGATCTCGTGCGTGATGACAATCTTGTATTTACTGCAACAGGCATTACCAATGGCGATTTGCTTAAAGGTA
TCTCCCGCAAAGGCAATTTAGCCAGTACTGAAACCATTTTAATTCGAGGAAAATCCCGCACAATTCGTAAAATTCAATCC
ATTCATTATTTGGATGACCTTTATAAAATTTTGAATATTTAG

Upstream 100 bases:

>100_bases
TAAAGCATTGAATAAAAATTTATTATGCAAACGATTACTCAGTGATAGAATGATGCTATTTTTACCATAATCTTGAAAAA
TAAGCAGAAGGAGAATAATA

Downstream 100 bases:

>100_bases
CTCAAGCAAACAACATTTCAATTAATTTAATCTGCTCTCCAAAAAATGGGACAAATTACAAATGGACAGAGCAGATTTTA
AGTATCATTTTTGAATAATT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNRALAIEFSRVTEAAALAAYTWLGRGDKNAADDAAVKAMRYMLNLIHMDAEIVIGEGEIDEAPMLYVGEKVGSGLGELV
SIAVDPIDGTHMTAMGQSNAISVLAAGGKNTFLKAPDMYMEKLVVGSNVKGIIDLNLPLEQNLRRIASKLGKSLSDLTVM
VLAKPRHDAVIKQIHNLGAKVLAIPDGDVAGSVLCCLPDAEVDLLYGIGGAPEGVAAAAAIRALGGDMQARLIPRNEVKS
DTEENKKIAANEIQRCAALGVKVNEVLKLEDLVRDDNLVFTATGITNGDLLKGISRKGNLASTETILIRGKSRTIRKIQS
IHYLDDLYKILNI

Sequences:

>Translated_333_residues
MNRALAIEFSRVTEAAALAAYTWLGRGDKNAADDAAVKAMRYMLNLIHMDAEIVIGEGEIDEAPMLYVGEKVGSGLGELV
SIAVDPIDGTHMTAMGQSNAISVLAAGGKNTFLKAPDMYMEKLVVGSNVKGIIDLNLPLEQNLRRIASKLGKSLSDLTVM
VLAKPRHDAVIKQIHNLGAKVLAIPDGDVAGSVLCCLPDAEVDLLYGIGGAPEGVAAAAAIRALGGDMQARLIPRNEVKS
DTEENKKIAANEIQRCAALGVKVNEVLKLEDLVRDDNLVFTATGITNGDLLKGISRKGNLASTETILIRGKSRTIRKIQS
IHYLDDLYKILNI
>Mature_333_residues
MNRALAIEFSRVTEAAALAAYTWLGRGDKNAADDAAVKAMRYMLNLIHMDAEIVIGEGEIDEAPMLYVGEKVGSGLGELV
SIAVDPIDGTHMTAMGQSNAISVLAAGGKNTFLKAPDMYMEKLVVGSNVKGIIDLNLPLEQNLRRIASKLGKSLSDLTVM
VLAKPRHDAVIKQIHNLGAKVLAIPDGDVAGSVLCCLPDAEVDLLYGIGGAPEGVAAAAAIRALGGDMQARLIPRNEVKS
DTEENKKIAANEIQRCAALGVKVNEVLKLEDLVRDDNLVFTATGITNGDLLKGISRKGNLASTETILIRGKSRTIRKIQS
IHYLDDLYKILNI

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family

Homologues:

Organism=Escherichia coli, GI1790360, Length=325, Percent_Identity=69.2307692307692, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1789298, Length=319, Percent_Identity=53.2915360501567, Blast_Score=328, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPX_HAEIN (P44811)

Other databases:

- EMBL:   L42023
- PIR:   B64085
- RefSeq:   NP_438827.1
- ProteinModelPortal:   P44811
- GeneID:   949705
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0667
- NMPDR:   fig|71421.1.peg.637
- TIGR:   HI_0667
- HOGENOM:   HBG284837
- OMA:   GTVRFIE
- ProtClustDB:   PRK09479
- BioCyc:   HINF71421:HI_0667-MONOMER
- BRENDA:   3.1.3.11
- GO:   GO:0005737
- InterPro:   IPR004464
- PIRSF:   PIRSF004532
- TIGRFAMs:   TIGR00330

Pfam domain/function: PF03320 FBPase_glpX

EC number: =3.1.3.11

Molecular weight: Translated: 35535; Mature: 35535

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: BINDING 119-119 BINDING 210-210

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRALAIEFSRVTEAAALAAYTWLGRGDKNAADDAAVKAMRYMLNLIHMDAEIVIGEGEI
CCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
DEAPMLYVGEKVGSGLGELVSIAVDPIDGTHMTAMGQSNAISVLAAGGKNTFLKAPDMYM
CCCCEEEECHHHCCCHHHHHHEEECCCCCCEEEECCCCCCEEEEEECCCCCEEECCHHHH
EKLVVGSNVKGIIDLNLPLEQNLRRIASKLGKSLSDLTVMVLAKPRHDAVIKQIHNLGAK
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHEEEEEEECCCHHHHHHHHHHCCCE
VLAIPDGDVAGSVLCCLPDAEVDLLYGIGGAPEGVAAAAAIRALGGDMQARLIPRNEVKS
EEEECCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCHHHCC
DTEENKKIAANEIQRCAALGVKVNEVLKLEDLVRDDNLVFTATGITNGDLLKGISRKGNL
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCCCC
ASTETILIRGKSRTIRKIQSIHYLDDLYKILNI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRALAIEFSRVTEAAALAAYTWLGRGDKNAADDAAVKAMRYMLNLIHMDAEIVIGEGEI
CCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
DEAPMLYVGEKVGSGLGELVSIAVDPIDGTHMTAMGQSNAISVLAAGGKNTFLKAPDMYM
CCCCEEEECHHHCCCHHHHHHEEECCCCCCEEEECCCCCCEEEEEECCCCCEEECCHHHH
EKLVVGSNVKGIIDLNLPLEQNLRRIASKLGKSLSDLTVMVLAKPRHDAVIKQIHNLGAK
HHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHEEEEEEECCCHHHHHHHHHHCCCE
VLAIPDGDVAGSVLCCLPDAEVDLLYGIGGAPEGVAAAAAIRALGGDMQARLIPRNEVKS
EEEECCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCHHHCC
DTEENKKIAANEIQRCAALGVKVNEVLKLEDLVRDDNLVFTATGITNGDLLKGISRKGNL
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCCCC
ASTETILIRGKSRTIRKIQSIHYLDDLYKILNI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800