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The map label for this gene is tfoX

Identifier: 16272544

GI number: 16272544

Start: 622876

End: 623529

Strand: Direct

Name: tfoX

Synonym: HI0601

Alternate gene names: 16272544

Gene position: 622876-623529 (Clockwise)

Preceding gene: 16272541

Following gene: 30995388

Centisome position: 34.03

GC content: 31.5

Gene sequence:

>654_bases
ATGAATATAAAGGATGAGCATATAGATAGCGTTTGCTCCTTGTTAGATCAGTTAGTAGGAAATGTTTCCTTTAAAAATCT
TTTTACTGGTTACGGTTTGTTTCACAAGGAAGAGACAATGTTTGCTATTTGGCAAAATAAAAAACTTTATTTACGCGGTG
AGGGTGTTCTCGCAATTCAATTAACTAAATTAGGTTGTGAACCTTTTACAACGAATGAATTGAATAAACGGTTTGTGCTT
TCACAATATTATGCACTTTCTGATCAGATTTTACGTAGTAATAGATTGTGTAGAAAATTGATTATTCTTTCTATTAAGCA
GATTCTTGAGCAGAAGCTAGAATGTACGTTAAGAAAATTGAATCGATTAAAGGATTTACCCAATTTAACGATTAAACATG
AAAGAGCTTTAATAAAAGTTGGTATTACAAATGTTGCGATGCTAAGAGAGATTGGCGCAGAAAATGCATTGGTGGAATTA
AAGAAAAGTGGCAGTGGTGCTACGCTTGATTTTTATTGGAAATTAGTATGTGCTTTGCAAAATAAAAATAGTCAGATGTT
AAGTCAAGCTGAAAAAGAGCGTTTATTGAAGAAATTAAACGAAGTTTGGAGAAAAAATGGCTTAAAAGGCTATAGAAAAT
TAGATGATGAATAA

Upstream 100 bases:

>100_bases
TGACATTTATATTTAGGTGTAGTAAAAATTTCATGATATAAATGAAATCAGAAGTACTTCTACTGACTCTTTTAAAATAA
TTATTCATTGGAGGTTTAAT

Downstream 100 bases:

>100_bases
AATTTGTTCATTCAAATAATTTMMMGCAAAAAGTACTTGCAAGGGATTTGAAAATCCCTATAATGCACCGCACACAACGA
CGCACTGTTGTGAAGTTTTT

Product: DNA transformation protein

Products: NA

Alternate protein names: Competence activator; Protein sxy

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNIKDEHIDSVCSLLDQLVGNVSFKNLFTGYGLFHKEETMFAIWQNKKLYLRGEGVLAIQLTKLGCEPFTTNELNKRFVL
SQYYALSDQILRSNRLCRKLIILSIKQILEQKLECTLRKLNRLKDLPNLTIKHERALIKVGITNVAMLREIGAENALVEL
KKSGSGATLDFYWKLVCALQNKNSQMLSQAEKERLLKKLNEVWRKNGLKGYRKLDDE

Sequences:

>Translated_217_residues
MNIKDEHIDSVCSLLDQLVGNVSFKNLFTGYGLFHKEETMFAIWQNKKLYLRGEGVLAIQLTKLGCEPFTTNELNKRFVL
SQYYALSDQILRSNRLCRKLIILSIKQILEQKLECTLRKLNRLKDLPNLTIKHERALIKVGITNVAMLREIGAENALVEL
KKSGSGATLDFYWKLVCALQNKNSQMLSQAEKERLLKKLNEVWRKNGLKGYRKLDDE
>Mature_217_residues
MNIKDEHIDSVCSLLDQLVGNVSFKNLFTGYGLFHKEETMFAIWQNKKLYLRGEGVLAIQLTKLGCEPFTTNELNKRFVL
SQYYALSDQILRSNRLCRKLIILSIKQILEQKLECTLRKLNRLKDLPNLTIKHERALIKVGITNVAMLREIGAENALVEL
KKSGSGATLDFYWKLVCALQNKNSQMLSQAEKERLLKKLNEVWRKNGLKGYRKLDDE

Specific function: Required for DNA transformation. Positively regulates gene required for DNA transformation (late competence-specific genes)

COG id: COG3070

COG function: function code K; Regulator of competence-specific genes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli sxy

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TFOX_HAEIN (P43779)

Other databases:

- EMBL:   U13205
- EMBL:   U13205
- EMBL:   L42023
- PIR:   B64080
- RefSeq:   NP_438758.1
- ProteinModelPortal:   P43779
- GeneID:   949645
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0601
- NMPDR:   fig|71421.1.peg.570
- TIGR:   HI_0601
- HOGENOM:   HBG495649
- OMA:   QFGGYSL
- ProtClustDB:   CLSK2518363
- BioCyc:   HINF71421:HI_0601-MONOMER
- GO:   GO:0006350
- InterPro:   IPR007077
- InterPro:   IPR007076

Pfam domain/function: PF04994 TfoX_C; PF04993 TfoX_N

EC number: NA

Molecular weight: Translated: 25075; Mature: 25075

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKDEHIDSVCSLLDQLVGNVSFKNLFTGYGLFHKEETMFAIWQNKKLYLRGEGVLAIQ
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEEECCCEEEEECCCEEEEE
LTKLGCEPFTTNELNKRFVLSQYYALSDQILRSNRLCRKLIILSIKQILEQKLECTLRKL
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRLKDLPNLTIKHERALIKVGITNVAMLREIGAENALVELKKSGSGATLDFYWKLVCALQ
HHHHCCCCCEEHHHHEEEEECHHHHHHHHHHCCCHHHHHEECCCCCCCHHHHHHHHHHHH
NKNSQMLSQAEKERLLKKLNEVWRKNGLKGYRKLDDE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
>Mature Secondary Structure
MNIKDEHIDSVCSLLDQLVGNVSFKNLFTGYGLFHKEETMFAIWQNKKLYLRGEGVLAIQ
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEEECCCEEEEECCCEEEEE
LTKLGCEPFTTNELNKRFVLSQYYALSDQILRSNRLCRKLIILSIKQILEQKLECTLRKL
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRLKDLPNLTIKHERALIKVGITNVAMLREIGAENALVELKKSGSGATLDFYWKLVCALQ
HHHHCCCCCEEHHHHEEEEECHHHHHHHHHHCCCHHHHHEECCCCCCCHHHHHHHHHHHH
NKNSQMLSQAEKERLLKKLNEVWRKNGLKGYRKLDDE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7724607; 7542800; 7961436