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The map label for this gene is znuB

Identifier: 16272356

GI number: 16272356

Start: 428072

End: 428857

Strand: Reverse

Name: znuB

Synonym: HI0407

Alternate gene names: 16272356

Gene position: 428857-428072 (Counterclockwise)

Preceding gene: 16272357

Following gene: 16272355

Centisome position: 23.43

GC content: 38.68

Gene sequence:

>786_bases
ATGTTTGAAATTTTATTTCCTGCCCTTTTAACAGGCATTGTGCTTTCGCTTATTACCGCGCCACTTGGCGTATTTGTGGT
GTGGCGTAAAATGGCTTATTTTGGCGACACCCTTTCTCATTCTGCCTTGCTCGGTGTAGCATTAGGTATTTTCTTACAAG
TCAATCCTTACATTGCGATTGTGGTGCTTACCTTAATTCTTGCTATCGCAATGGTGTGGTTAGAAAGCAATACGCAATTT
TCTATTGATACCTTGCTCGGTATTATCGCCCATAGCTGTTTATCTCTCGGGGTTGTGACAGTAGGATTATTACGGAATGT
ACGGGTAGATTTAATGAATTATTTATTTGGGGATTTACTCGCGATTAATTATACGGATTTAATTTATATCGGCATTGGCG
TGATAATTGTGCTTTCAACATTAATTTACTTTTGGCAATCCTTACTTTCCACCACCGTATCGCCAGAACTCGCGCAAGTT
GAAGGTATTAATATCAAAAAAATGCGTTTTATTTTAATGATATTAACCGCATTGACTATTGCCTTGAGTATGAAATTTGT
CGGTGCATTAATTATCACATCCTTATTAATAATCCCTGCGGCAACCGCTCGTCGCTTTGCAAGAACACCAGAATCTATGG
TGGGCTGGGCGATTATTATGAGTATGTTATCGATTATAGGTGGACTAATCTTATCAGCCTTTTATGATACTGCTGCTGGG
CCTTCTGTTGTGATTTGTTCCGCGTTTTTATTTGTCTTATCGCTCTTTAAAAGAGAGCGATTATAA

Upstream 100 bases:

>100_bases
TCGGCTTTTATACCCATCATCACAATCATCATCACACTTTACACGGAGATGTGTGCGGTTGTAATTCATCAGCAGTGCAT
TGTCAAAATAAGGATAAATA

Downstream 100 bases:

>100_bases
GCTTGCCCAACCAGTGAAAACCATTTGCGCCACAGTTTAATTCCTTGATAAAGTGCGGTCGATTTTTACGGTCTTTTTAG
GATAACAAAATGAACCAAGA

Product: hypothetical protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAIVVLTLILAIAMVWLESNTQF
SIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLLAINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQV
EGINIKKMRFILMILTALTIALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAG
PSVVICSAFLFVLSLFKRERL

Sequences:

>Translated_261_residues
MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAIVVLTLILAIAMVWLESNTQF
SIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLLAINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQV
EGINIKKMRFILMILTALTIALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAG
PSVVICSAFLFVLSLFKRERL
>Mature_261_residues
MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAIVVLTLILAIAMVWLESNTQF
SIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLLAINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQV
EGINIKKMRFILMILTALTIALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAG
PSVVICSAFLFVLSLFKRERL

Specific function: Involved in the high-affinity zinc uptake transport system

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=259, Percent_Identity=60.6177606177606, Blast_Score=328, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUB_HAEIN (P44691)

Other databases:

- EMBL:   L42023
- PIR:   A64066
- RefSeq:   NP_438569.1
- ProteinModelPortal:   P44691
- GeneID:   949507
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0407
- NMPDR:   fig|71421.1.peg.382
- TIGR:   HI_0407
- HOGENOM:   HBG733179
- OMA:   FMHEVRI
- ProtClustDB:   CLSK870021
- BioCyc:   HINF71421:HI_0407-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 28466; Mature: 28466

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcc66264)-; HASH(0xcb16b80)-; HASH(0xcadc640)-; HASH(0xcbc73a4)-; HASH(0xc0b29e0)-; HASH(0xc2b4638)-; HASH(0xc3910a0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
VVLTLILAIAMVWLESNTQFSIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQVEGINIKKMRFILMILTALTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHH
ALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSVVICSAFLFVLSLFKRERL
CHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MFEILFPALLTGIVLSLITAPLGVFVVWRKMAYFGDTLSHSALLGVALGIFLQVNPYIAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
VVLTLILAIAMVWLESNTQFSIDTLLGIIAHSCLSLGVVTVGLLRNVRVDLMNYLFGDLL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AINYTDLIYIGIGVIIVLSTLIYFWQSLLSTTVSPELAQVEGINIKKMRFILMILTALTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHH
ALSMKFVGALIITSLLIIPAATARRFARTPESMVGWAIIMSMLSIIGGLILSAFYDTAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSVVICSAFLFVLSLFKRERL
CHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800