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The map label for this gene is yfeD [C]

Identifier: 16272308

GI number: 16272308

Start: 383822

End: 384637

Strand: Reverse

Name: yfeD [C]

Synonym: HI0359

Alternate gene names: 16272308

Gene position: 384637-383822 (Counterclockwise)

Preceding gene: 16272309

Following gene: 16272303

Centisome position: 21.02

GC content: 35.66

Gene sequence:

>816_bases
ATGTTTGATTGGCTTTTAGAACCGCTACAATTTGAGTTTATGCAAAATGCCTTATTGACCGCATTGATTGTTTCGATTAT
CTGTGCGTTACTTTCTTGCTATTTAGTCTTGAAAGGTTGGTCATTAATGGGTGATGCAATTTCTCACGCTGTATTACCTG
GTATTGTACTTGCTTATTTGGCAGGAATTCCTTTAGCCATTGGTGCATTTTTCTCGGGTATTTTTTGTTCGCTTGGTGTG
GGATATTTGAAAGAAAATAGCCGTATAAAAGAAGATACCGCAATGGGCATTGTATTTTCTGGAATGTTTGCCATTGGTCT
TGTTATGTTTACCAAAATTCAAACAGAAGAGCATTTAACCCATATTTTGTTTGGTAATGTGTTGGGTGTAAGTCATCAAG
AACTTATTCAAAGTGCGGTCATTTCTGCGATAATTTTTTGTCTGATTGTCTTTAAACGTAAAGACTTTCTGCTTTATTGT
TTTGATCCAAGTCACGCCCGTGTTGCAGGACTTTCTCCTAAAATTTTACATTATGGTTTATTAATTCTACTTGCTTTAAC
CATTGTAAGCACGATGCAAGTGGTAGGTGTTATTTTGGTGGTGGCAATGTTAATTGCACCAGGAATTACCGCACTTACTC
TTACTAAATCTTTTGATAAAATGTTATGGGTTGCTATTGCAAGTTCCATTGCATCAAGCTTAATTGGCGTAATATTGAGC
TATCATTTTGATGCCTCAACAGGTGCTTGTATTATTCTTCTGCAAGCCGCATTTTTTGTTATAGCATTAGCTTATAGCAA
GATTAGAATAAGATAA

Upstream 100 bases:

>100_bases
GGCGGTGTGATTGTGACATTGCAAACATTATTGTTTTTAGTCGCTTTCTTATTTTCACCAAAATATGGCTTATTAACTCG
TAATAAAAAGGCGGTAGAAA

Downstream 100 bases:

>100_bases
TTTTTCTACCCCTCTTTTCTCAAAGAGGAGGTAGAAAATCGCAATAAATTTATCCGTTTGGAGATAAATAAAGTTATTCG
TCTAATCGCCAATCTAAGCC

Product: iron (chelated) ABC transporter permease

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYLAGIPLAIGAFFSGIFCSLGV
GYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLTHILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYC
FDPSHARVAGLSPKILHYGLLILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILS
YHFDASTGACIILLQAAFFVIALAYSKIRIR

Sequences:

>Translated_271_residues
MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYLAGIPLAIGAFFSGIFCSLGV
GYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLTHILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYC
FDPSHARVAGLSPKILHYGLLILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILS
YHFDASTGACIILLQAAFFVIALAYSKIRIR
>Mature_271_residues
MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYLAGIPLAIGAFFSGIFCSLGV
GYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLTHILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYC
FDPSHARVAGLSPKILHYGLLILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILS
YHFDASTGACIILLQAAFFVIALAYSKIRIR

Specific function: Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron (Potential)

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=257, Percent_Identity=24.5136186770428, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y359_HAEIN (P44660)

Other databases:

- EMBL:   L42023
- PIR:   G64149
- RefSeq:   NP_438521.1
- ProteinModelPortal:   P44660
- GeneID:   949465
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0359
- NMPDR:   fig|71421.1.peg.334
- TIGR:   HI_0359
- HOGENOM:   HBG733179
- OMA:   PFQFPFM
- ProtClustDB:   CLSK2459764
- BioCyc:   HINF71421:HI_0359-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 29393; Mature: 29393

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc99c70c)-; HASH(0xbcdcf5c)-; HASH(0xb58c218)-; HASH(0xb1aad0c)-; HASH(0x96cd550)-; HASH(0xb19c180)-; HASH(0xc8bd7b0)-; HASH(0xbc2d760)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIPLAIGAFFSGIFCSLGVGYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLT
HHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYCFDPSHARVAGLSPKILHYGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHH
LILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHFDASTGACIILLQAAFFVIALAYSKIRIR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFDWLLEPLQFEFMQNALLTALIVSIICALLSCYLVLKGWSLMGDAISHAVLPGIVLAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIPLAIGAFFSGIFCSLGVGYLKENSRIKEDTAMGIVFSGMFAIGLVMFTKIQTEEHLT
HHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILFGNVLGVSHQELIQSAVISAIIFCLIVFKRKDFLLYCFDPSHARVAGLSPKILHYGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHH
LILLALTIVSTMQVVGVILVVAMLIAPGITALTLTKSFDKMLWVAIASSIASSLIGVILS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHFDASTGACIILLQAAFFVIALAYSKIRIR
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800