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The map label for this gene is mogA

Identifier: 16272288

GI number: 16272288

Start: 363918

End: 364511

Strand: Direct

Name: mogA

Synonym: HI0336

Alternate gene names: 16272288

Gene position: 363918-364511 (Clockwise)

Preceding gene: 16272287

Following gene: 16272289

Centisome position: 19.88

GC content: 42.76

Gene sequence:

>594_bases
ATGACCGCACTTTTAAAAATTGGTCTGGTGTCTGTTTCTGATCGCGCATCAGCAGGCGTGTATCAAGATCAAGGTATCCC
AGAATTACAGGCTTGGTTAGAACAAGCGTTAGTAGATCCTTTCCATTTAGAAACAAGATTAATCCCCGATGAACAGCCAG
TTATTGAACAAACCTTAAAAGAGCTGGTGGATGAACAAGGTTGCCATTTAGTGCTGACAACTGGTGGAACTGGGCCAGCA
AAACGCGATGTAACGCCTGATGCAACCCTTGCGGTAGCGGATCGAGAAATGCCAGGTTTTGGCGAACAAATGCGTCAAGT
GAGTTTGCATTTTGTGCCTACCGCAATTTTATCTCGCCAAGTGGGTGTAATTCGTAAGGAAAGCCTGATTTTAAATCTTC
CTGGGCAACCTAAAGCGATTAAAGAAACCTTAGAGGGCGTAAAAGATAAAGAAGGAAATGTGCTTGTAAAAGGCATTTTT
AGCGCAGTGCCTTATTGTTTGCAACTGATTAACGGCTTATATATTGATACCAAGCCTGAAATCATCGAAAGTTTCCGTCC
TAAATCTGCAAGACGCGAAAATCTGGAGAAATAG

Upstream 100 bases:

>100_bases
GGAATTTTATTCTTCTAACCCTCCAAAAGTGCGGTAAGTTTTTACCGCATTTTTGATTTATCCAATCACGTCAAAATCAT
TTATAAAAATAAGGAAAAAT

Downstream 100 bases:

>100_bases
CATGAAAAAAATCGAAGCAATGATTAAACCCTTTAAATTAGACGATGTGCGAGAAAGTCTTTCAGATATTGGTATTTCAG
GTATGACAATCACAGAAGTA

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPVIEQTLKELVDEQGCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIF
SAVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK

Sequences:

>Translated_197_residues
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPVIEQTLKELVDEQGCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIF
SAVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK
>Mature_196_residues
TALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPVIEQTLKELVDEQGCHLVLTTGGTGPAK
RDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFS
AVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family

Homologues:

Organism=Homo sapiens, GI66932975, Length=175, Percent_Identity=33.7142857142857, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI10880983, Length=175, Percent_Identity=33.7142857142857, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786190, Length=189, Percent_Identity=79.3650793650794, Blast_Score=323, Evalue=5e-90,
Organism=Escherichia coli, GI1787000, Length=102, Percent_Identity=32.3529411764706, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17564954, Length=149, Percent_Identity=36.241610738255, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17136978, Length=144, Percent_Identity=32.6388888888889, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24638841, Length=144, Percent_Identity=32.6388888888889, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOG_HAEIN (P44645)

Other databases:

- EMBL:   L42023
- PIR:   D64148
- RefSeq:   NP_438500.1
- ProteinModelPortal:   P44645
- SMR:   P44645
- GeneID:   949444
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0336
- NMPDR:   fig|71421.1.peg.315
- TIGR:   HI_0336
- HOGENOM:   HBG460560
- OMA:   PYCVDLI
- ProtClustDB:   PRK09417
- BioCyc:   HINF71421:HI_0336-MONOMER
- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 21691; Mature: 21560

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPVIEQTLK
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHH
ELVDEQGCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFSAVPYCLQLINGLYIDTKPE
HHHEEECCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
IIESFRPKSARRENLEK
HHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
TALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPVIEQTLK
CCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHH
ELVDEQGCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFSAVPYCLQLINGLYIDTKPE
HHHEEECCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
IIESFRPKSARRENLEK
HHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023