Click here to switch to the map view.

The map label for this gene is ruvC [H]

Identifier: 16272268

GI number: 16272268

Start: 345746

End: 346318

Strand: Reverse

Name: ruvC [H]

Synonym: HI0314

Alternate gene names: 16272268

Gene position: 346318-345746 (Counterclockwise)

Preceding gene: 16272269

Following gene: 16272267

Centisome position: 18.92

GC content: 41.54

Gene sequence:

>573_bases
ATGAGCATTATTTTAGGTATTGACCCAGGCTCTCGCGTAACTGGTTACGGTGTGATTCGTCAAACAGGAAAACATTTAGA
ATATCTCGGTAGTGGCGCAATTCGTACTCAAGTTGAAGATTTACCCACCCGTTTGAAACGCATTTATGCTGGAGTAACTG
AAATCATCACGCAATTTCAACCTAATATGTTTGCGATTGAGCAAGTGTTTATGGCGAAGAATGCGGATTCAGCATTGAAA
CTTGGGCAGGCTCGCGGCACGGCGATTGTTGCAGCGGTAAATAATGATTTACCTGTTTTTGAATATGCCGCACGTTTAGT
AAAACAAACAGTGGTGGGCATTGGTTCCGCTGATAAAGTGCAAGTGCAAGAAATGGTGACTCGTATTTTGAAGTTGTCAG
ATAAACCTCAAGCCGATGCAGCGGATGCGTTGGCTATTGCGATTACACACGCGCATTCTATTCAACATTCTTTACATATT
GCCAATTCTGTGAAAATGACAGAAACGCAAGAAAAAATGACCGCACTTTTAAAGACCAGATATAGCCGAGGACGCTTTAG
ATTAAAAATTTAA

Upstream 100 bases:

>100_bases
CAAAACGTATATCACAACGGAGAAATCTGTGACGAAGTGGCATCTCAACTTTAATGATGCAATAAATGGGTAATTTAATT
ACCCATTTTTTATAGAAATT

Downstream 100 bases:

>100_bases
CTGGATGTTCGTCCAGTTTTATTTTATTCTATGCGTTAATTTTTTTATCATTCGGAAGAATTATGATCGGTCGCTTACAA
GGCATTCTTTTAGAAAAACA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPNMFAIEQVFMAKNADSALK
LGQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHI
ANSVKMTETQEKMTALLKTRYSRGRFRLKI

Sequences:

>Translated_190_residues
MSIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPNMFAIEQVFMAKNADSALK
LGQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHI
ANSVKMTETQEKMTALLKTRYSRGRFRLKI
>Mature_189_residues
SIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPNMFAIEQVFMAKNADSALKL
GQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIA
NSVKMTETQEKMTALLKTRYSRGRFRLKI

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=187, Percent_Identity=71.6577540106952, Blast_Score=239, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 20816; Mature: 20684

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQ
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNMFAIEQVFMAKNADSALKLGQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKV
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHH
QVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIANSVKMTETQEKMTALLKTR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YSRGRFRLKI
HCCCEEEEEC
>Mature Secondary Structure 
SIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQ
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNMFAIEQVFMAKNADSALKLGQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKV
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHH
QVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIANSVKMTETQEKMTALLKTR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YSRGRFRLKI
HCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA