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The map label for this gene is copA [C]

Identifier: 16272246

GI number: 16272246

Start: 327506

End: 327712

Strand: Reverse

Name: copA [C]

Synonym: HI0291

Alternate gene names: 16272246

Gene position: 327712-327506 (Counterclockwise)

Preceding gene: 16272247

Following gene: 16272245

Centisome position: 17.91

GC content: 35.27

Gene sequence:

>207_bases
ATGAAAACTATCACATTAAACATAAAAGGCATACATTGCGGCTGTTGCGTAAAAAATCTTACTCAAGTTTTAACTGAATT
AGATGGTGTACAATCTGCTGATGTGCAATTAGAGGGTAAAGCAAATATTACTTTTGATGAAAATCGAGTCAATGTTGCAC
AGTTGATTGAGGTCATTGAAGATGCTGGATTTGACGCCACAGAGTAA

Upstream 100 bases:

>100_bases
ATGCTGGATTTGACGCCACAGAGTAAAAAAATTTCAATTCAGATTGGTGGGATGGCCTGCCAATCGCATTCATCAATAAA
ACAACTAACAAGGAGTAAAA

Downstream 100 bases:

>100_bases
AAAAATTTCAATTCAGATTGGTGGGATGACCTGCCAATCTTGTGCCAATCGCATTGAAAAAGTTTTAAATAAAAAACCAT
TTGTGCAACAAGCAGGCGTA

Product: periplasmic mercury transport-like protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 68; Mature: 68

Protein sequence:

>68_residues
MKTITLNIKGIHCGCCVKNLTQVLTELDGVQSADVQLEGKANITFDENRVNVAQLIEVIEDAGFDATE

Sequences:

>Translated_68_residues
MKTITLNIKGIHCGCCVKNLTQVLTELDGVQSADVQLEGKANITFDENRVNVAQLIEVIEDAGFDATE
>Mature_68_residues
MKTITLNIKGIHCGCCVKNLTQVLTELDGVQSADVQLEGKANITFDENRVNVAQLIEVIEDAGFDATE

Specific function: Involved In Copper Efflux. [C]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y291_HAEIN (P43979)

Other databases:

- EMBL:   L42023
- PIR:   F64005
- RefSeq:   NP_438458.1
- ProteinModelPortal:   P43979
- SMR:   P43979
- GeneID:   949416
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0291
- NMPDR:   fig|71421.1.peg.273
- TIGR:   HI_0291
- HOGENOM:   HBG744819
- OMA:   LENACAE
- ProtClustDB:   CLSK789900
- BioCyc:   HINF71421:HI_0291-MONOMER
- GO:   GO:0016020
- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121
- PANTHER:   PTHR11939

Pfam domain/function: PF00403 HMA; SSF55008 HeavyMe_transpt

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 7378; Mature: 7378

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS01047 HMA_1; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTITLNIKGIHCGCCVKNLTQVLTELDGVQSADVQLEGKANITFDENRVNVAQLIEVIE
CCEEEEEECEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
DAGFDATE
HCCCCCCC
>Mature Secondary Structure
MKTITLNIKGIHCGCCVKNLTQVLTELDGVQSADVQLEGKANITFDENRVNVAQLIEVIE
CCEEEEEECEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
DAGFDATE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023