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The map label for this gene is mltF [H]

Identifier: 16272195

GI number: 16272195

Start: 263591

End: 264979

Strand: Direct

Name: mltF [H]

Synonym: HI0232

Alternate gene names: 16272195

Gene position: 263591-264979 (Clockwise)

Preceding gene: 16272194

Following gene: 16272208

Centisome position: 14.4

GC content: 34.99

Gene sequence:

>1389_bases
ATGGTGTTCCCATGGCAATTTTTACGTCATACTGAAGAAAATCATTATACTGCAATTCAAGCTAGGGGATCACTTTATGT
AGGAACAATAAATAACCAGATTTCTTATTTTATTAATAAAGATAGCGAACGAGGCTTTGAATATGAATTAGCCAAAGCAT
TTGCTGATACTTTAGGCGTAGAACTCGAAATGAAAATTTTCGATAATCAAGAGCAGTTATTTGATGAACTTGATAAACAC
AATATTGATTTAGCTGCCGCCCACCTTTTATACCATCCTAAAAATGCGGAACGTTTCCAAATAGGTCCTGCATATCATTC
TGCTTCATGGCAATTAGCTTATCGAAAAAATGAAAATCGTCCTAAAAATTTAGGTAACGTAAAGAAAGATATTTATATCT
CAAATAATTTAGCATTAGAAGAAACGCTAAAAGAATTACAAAAACAATATCCACAATTAATTTGGAAAAGAAATCAAGCA
CTTACTCAAGAAGAACTATTACTACAACTGGCTGAAGGCAAAATTCCTTACGTTATTGCAAATTCTATTGATATTGCTGC
AATTCAACAAATCAAACCAGAGTTAGCCATTGCCTTTGATATTACTGATGAAGCAAACGTTCACTGGTATTTACCCAATA
ACCCCTACCGCGATCTACAAACGGCTTTACTCAATTTTATGAATAATGCCGAAGAAACGGGACTTTTAGATAATTTAAAA
GAAAAATATTTAGGACATATTTCACAATTTGATTACGTGGATACGCGCTCTTATATGAACGCAATTGAAAATACCCTGCC
ACAATTCTCACCGCTCTTTGAAAAATACAAAGGTGAATTAGATTGGCGACTACTCGCAGCAGTGGCTTATCAAGAATCTC
ATTGGAATCCTGACGCAACATCGCCAACTGGAGTACGTGGCATAATGATGCTCACCAAAAATACCGCACAACATATGAAA
ATCAGTGATAGAACAGATCCTGAACAAAGTATTAAAGCTGGTTCAGAGTATTTACACTGGTTGATTAGTCAGCTTCCTGA
AAGCATTGAAAAGGAAGAAAGAATTTGGTTTGCCTTAGTTGCCTATAACATAGGACTCGGTCACTTAATTGATGCACGCC
GTTTAACTCAAAATCTTGGAGGAAATCCAGATAATTGGTTCGATGTGAAAAAAAATCTGCCTTTATTAGCAGAAAAACGC
TATTATTCCCAACTGAAATACGGCTATGCGCGAGGCTATGAAGCCCATCAATATGTAGAAAATATTCGCCGCTATATGAA
TAGCATAGTGAATTATCATCGAGTCCAAGAAAATCAAACAACGAATGATAATGCCAACAACGAAAGTGCGGTTAAAAATT
TAGAAGAAATAAAAGAAAATAAGGATTAA

Upstream 100 bases:

>100_bases
TTGGCTACAATCCCATAACTTTTTTATATAGGAAAAATCATTGAAAGGTCTTTTTTTACGTATTATTACTGCTCTAGCGT
TATTATTTTGGGCTATTGAT

Downstream 100 bases:

>100_bases
TAAAATGTTAAAACGTAAAACTTTTCTTAAAAAGAAAGCTAATTTACAACAAAGTTCTTTATCACGTAATCTACGTTTAA
GACGTTTAAAACACCGCAAA

Product: putative transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGVELEMKIFDNQEQLFDELDKH
NIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQA
LTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNNPYRDLQTALLNFMNNAEETGLLDNLK
EKYLGHISQFDYVDTRSYMNAIENTLPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDATSPTGVRGIMMLTKNTAQHMK
ISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLGGNPDNWFDVKKNLPLLAEKR
YYSQLKYGYARGYEAHQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKENKD

Sequences:

>Translated_462_residues
MVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGVELEMKIFDNQEQLFDELDKH
NIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQA
LTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNNPYRDLQTALLNFMNNAEETGLLDNLK
EKYLGHISQFDYVDTRSYMNAIENTLPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDATSPTGVRGIMMLTKNTAQHMK
ISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLGGNPDNWFDVKKNLPLLAEKR
YYSQLKYGYARGYEAHQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKENKD
>Mature_462_residues
MVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGVELEMKIFDNQEQLFDELDKH
NIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENRPKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQA
LTQEELLLQLAEGKIPYVIANSIDIAAIQQIKPELAIAFDITDEANVHWYLPNNPYRDLQTALLNFMNNAEETGLLDNLK
EKYLGHISQFDYVDTRSYMNAIENTLPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDATSPTGVRGIMMLTKNTAQHMK
ISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALVAYNIGLGHLIDARRLTQNLGGNPDNWFDVKKNLPLLAEKR
YYSQLKYGYARGYEAHQYVENIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKENKD

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=436, Percent_Identity=51.3761467889908, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 53819; Mature: 53819

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGV
CCCCHHHHHCCCCCCEEEEEECCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCC
ELEMKIFDNQEQLFDELDKHNIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENR
EEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCC
PKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQALTQEELLLQLAEGKIPYVIA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
NSIDIAAIQQIKPELAIAFDITDEANVHWYLPNNPYRDLQTALLNFMNNAEETGLLDNLK
CCCCHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCHHCCHHHHHH
EKYLGHISQFDYVDTRSYMNAIENTLPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDAT
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
SPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALV
CCCCCCEEEEEECCCHHHCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEH
AYNIGLGHLIDARRLTQNLGGNPDNWFDVKKNLPLLAEKRYYSQLKYGYARGYEAHQYVE
HHHCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
NIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKENKD
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVFPWQFLRHTEENHYTAIQARGSLYVGTINNQISYFINKDSERGFEYELAKAFADTLGV
CCCCHHHHHCCCCCCEEEEEECCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCC
ELEMKIFDNQEQLFDELDKHNIDLAAAHLLYHPKNAERFQIGPAYHSASWQLAYRKNENR
EEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCC
PKNLGNVKKDIYISNNLALEETLKELQKQYPQLIWKRNQALTQEELLLQLAEGKIPYVIA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
NSIDIAAIQQIKPELAIAFDITDEANVHWYLPNNPYRDLQTALLNFMNNAEETGLLDNLK
CCCCHHHHHHCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCHHCCHHHHHH
EKYLGHISQFDYVDTRSYMNAIENTLPQFSPLFEKYKGELDWRLLAAVAYQESHWNPDAT
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
SPTGVRGIMMLTKNTAQHMKISDRTDPEQSIKAGSEYLHWLISQLPESIEKEERIWFALV
CCCCCCEEEEEECCCHHHCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEH
AYNIGLGHLIDARRLTQNLGGNPDNWFDVKKNLPLLAEKRYYSQLKYGYARGYEAHQYVE
HHHCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
NIRRYMNSIVNYHRVQENQTTNDNANNESAVKNLEEIKENKD
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA