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The map label for this gene is aroB [H]

Identifier: 16272171

GI number: 16272171

Start: 222762

End: 223850

Strand: Direct

Name: aroB [H]

Synonym: HI0208

Alternate gene names: 16272171

Gene position: 222762-223850 (Clockwise)

Preceding gene: 16272170

Following gene: 16272172

Centisome position: 12.17

GC content: 42.61

Gene sequence:

>1089_bases
ATGCTGTGCGTCAACGTGGAATTGCAAGAGCGTCGCTATCCTATTTTAATTGGTAGCGGATTGTTACAAGATGAACGTAG
TTACCCGATTAAACGTGGAGATCGCGTGATGATTGTAACGAATCCCACGGTTGCACAGTTTTATCTTGATACAGTCATCT
ATGCGTTGGAAAAACGTGGTTGCGTAGTCGATCATGTTTTATTGCCAGATGGCGAAAAATACAAAACACTTGAATCTTTA
AACTTAATTTTCACCGCACTTTTGCAAGGTAATCATGGGCGAGATACCACGATTATTGCATTGGGCGGTGGCGTAATTGG
CGATGTTGCTGGCTTTGCTGCGGCAAGTTATCAGCGCGGCGTGCGTTTAATTCAAATTCCAACAACATTGCTTTCACAAG
TGGATTCTTCAGTGGGCGGTAAAACGGCGGTTAATCATGAATTAGGCAAAAATATGATTGGCGCGTTCTATCAGCCATCA
ATGGTTATTATTGATACGCTCACGCTTAATACACTTCCTAAACGTGAAGTAAACGCGGGGCTTGCCGAAGTTATCAAATA
TGGTGCCATTTTAGATTACGAATTTTTTGAATGGCTAGAGCAACATATTGATGAACTTGTCGCTTTGCATCCTGAGGCGC
TTCAACATTGTATTTCTCGTTGTTGCCAAATTAAAGCAGATGTTGTCGCGAGAGATGAAACAGAAAAAGGCGATCGTGCA
TTGCTTAATCTTGGACATACTTTTGGACATGCCATTGAAACTCACTTAGGTTATGGAAACTGGCTTCATGGTGAAGCTGT
TTCTACGGGAATGATGATGGCAGCGGCGCTTTCGGAAGAACTTGGAGATATTTCTATTGCAGATGTGTCTCGCCTTGAAA
AATTACTTGCTCGTGCCAATTTGCCCACCGTATCTCCAGATACGATGCAGCCGGAGGACTATTTACCGCATATGATGCGT
GATAAAAAAGTTCTATCGGGTAAATTGCGTCTGGTATTACTCAAATCTCTAGGTCAAGCTTATGTGGCGAATGATACCGA
ACATACCCTCGTGTTAAACGCAATTCGTCGTTGTACTCAAACGGATTAA

Upstream 100 bases:

>100_bases
GATGAACAAAATGCCAAAATAATGGTAAATCAAATTGTTGATTTAATTGATAATATGAATGGGTTGAATGGTGCACTTTA
AACACACCTAAGGATAAATT

Downstream 100 bases:

>100_bases
GATGTTACGTCCGAAAAAACAATCTTTAAAACCTAAGTTAAAACACCGTCCATTTTTAAAATGGGCGGGGGGAAAATTTC
GTTTAACGGACGAGATAAAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESL
NLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRGVRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPS
MVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRA
LLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMR
DKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQTD

Sequences:

>Translated_362_residues
MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESL
NLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRGVRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPS
MVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRA
LLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMR
DKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQTD
>Mature_362_residues
MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESL
NLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRGVRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPS
MVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRA
LLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMR
DKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQTD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=354, Percent_Identity=62.4293785310734, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6320332, Length=315, Percent_Identity=41.2698412698413, Blast_Score=195, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39920; Mature: 39920

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRG
CEEEEEEHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCC
CVVDHVLLPDGEKYKTLESLNLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRG
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
VRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPSMVIIDTLTLNTLPKREVNAG
CEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHH
LAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHH
LLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARAN
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHCC
LPTVSPDTMQPEDYLPHMMRDKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHCC
TD
CC
>Mature Secondary Structure
MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRG
CEEEEEEHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCC
CVVDHVLLPDGEKYKTLESLNLIFTALLQGNHGRDTTIIALGGGVIGDVAGFAAASYQRG
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
VRLIQIPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPSMVIIDTLTLNTLPKREVNAG
CEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHH
LAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHH
LLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAALSEELGDISIADVSRLEKLLARAN
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHCC
LPTVSPDTMQPEDYLPHMMRDKKVLSGKLRLVLLKSLGQAYVANDTEHTLVLNAIRRCTQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHCC
TD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA