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The map label for this gene is aroC [H]

Identifier: 16272160

GI number: 16272160

Start: 212017

End: 213090

Strand: Direct

Name: aroC [H]

Synonym: HI0196

Alternate gene names: 16272160

Gene position: 212017-213090 (Clockwise)

Preceding gene: 16272159

Following gene: 16272161

Centisome position: 11.58

GC content: 42.27

Gene sequence:

>1074_bases
ATGGCTGGTAATACAATTGGACAACTTTTCCGTGTGACAACCTTTGGAGAGTCACATGGTATTGCATTAGGCTGTATCGT
TGATGGCGTGCCACCAAATCTCGAATTATCCGAGAAAGATATTCAGCCAGATTTAGATCGTCGTAAACCAGGAACATCTC
GATATACGACGCCTCGTCGTGAAGATGACGAAGTTCAAATTTTATCTGGTGTGTTTGAAGGAAAAACCACAGGCACAAGT
ATTGGGATGATCATTAAAAATGGAGATCAGCGTTCGCAAGATTATGGTGACATTAAAGATCGTTTCCGCCCAGGTCATGC
GGATTTTACCTATCAGCAAAAGTATGGAATCCGTGATTATCGTGGCGGTGGGCGTTCGTCAGCACGTGAAACAGCGATGC
GGGTTGCTGCAGGGGCTATTGCGAAAAAATATTTACGCGAACATTTTGGCATTGAGGTGCGAGGTTTTTTAAGCCAAATC
GGTAATATAAAAATTGCTCCGCAGAAAGTGGGACAAATTGATTGGGAAAAGGTAAACAGTAATCCATTCTTTTGTCCTGA
TGAAAGTGCGGTAGAAAAATTCGATGAATTGATCCGTGAACTTAAAAAAGAAGGAGATTCTATTGGCGCAAAACTTACTG
TTATTGCAGAAAATGTACCTGTAGGATTGGGCGAGCCAGTATTTGACCGTTTAGATGCCGATCTTGCTCACGCATTAATG
GGAATTAATGCAGTAAAAGGTGTAGAAATTGGCGATGGCTTTGCTGTGGTTGAACAACGAGGTTCGGAACATCGTGATGA
AATGACACCTAATGGCTTTGAAAGTAATCATGCAGGCGGTATTTTAGGCGGAATTAGTTCAGGACAACCAATTATCGCCA
CTATTGCACTAAAACCAACTTCAAGCATTACGATTCCTGGTCGTTCAATCAATCTTAATGGTGAAGCCGTAGAAGTTGTA
ACAAAAGGTCGTCACGATCCTTGTGTGGGGATTCGTGCTGTGCCAATTGCGGAAGCTATGGTGGCGATTGTCTTATTAGA
TCATCTCTTACGTTTTAAGGCACAGTGTAAATAA

Upstream 100 bases:

>100_bases
TAATATTGATATTGCCTTTAATCAATTAGATGTATTTATCAAAAATAATGATACAGGCGAAGAAATTCCTTTTGTTGATG
TAAAAAAATAAGGGCAAATT

Downstream 100 bases:

>100_bases
TCCTGTACCTAGGGTAGTATACTCTAGGTTAGTTCTTCAATAGGACTGAACCTAGGATATACTTACCTACAGCAAAACTT
TAGAATGAATAAAATTTTAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MAGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQI
GNIKIAPQKVGQIDWEKVNSNPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALM
GINAVKGVEIGDGFAVVEQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPTSSITIPGRSINLNGEAVEVV
TKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK

Sequences:

>Translated_357_residues
MAGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQI
GNIKIAPQKVGQIDWEKVNSNPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALM
GINAVKGVEIGDGFAVVEQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPTSSITIPGRSINLNGEAVEVV
TKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK
>Mature_356_residues
AGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTSI
GMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQIG
NIKIAPQKVGQIDWEKVNSNPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALMG
INAVKGVEIGDGFAVVEQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPTSSITIPGRSINLNGEAVEVVT
KGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=355, Percent_Identity=76.3380281690141, Blast_Score=535, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=48.1081081081081, Blast_Score=326, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38691; Mature: 38560

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRR
CCCCHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQIGNIKIAPQKVGQIDWEKVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECHHHHCCCCCEEECC
NPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALM
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GINAVKGVEIGDGFAVVEQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPT
HHHHHCCEEECCCHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCC
SSITIPGRSINLNGEAVEVVTKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK
CEEEECCCEEECCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRR
CCCHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQIGNIKIAPQKVGQIDWEKVNS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECHHHHCCCCCEEECC
NPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALM
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
GINAVKGVEIGDGFAVVEQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPT
HHHHHCCEEECCCHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCC
SSITIPGRSINLNGEAVEVVTKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK
CEEEECCCEEECCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA