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The map label for this gene is htpG [H]

Identifier: 16272078

GI number: 16272078

Start: 110269

End: 112164

Strand: Reverse

Name: htpG [H]

Synonym: HI0104

Alternate gene names: 16272078

Gene position: 112164-110269 (Counterclockwise)

Preceding gene: 16272080

Following gene: 16272077

Centisome position: 6.13

GC content: 37.92

Gene sequence:

>1896_bases
ATGAAGGAAAAAATTATGTCACAAAATCAAGAAACTCGCGGATTCCAATCTGAAGTCAAACAACTACTCCAATTAATGAT
TCATTCTTTGTACTCTAACAAAGAAATTTTCTTACGTGAATTGATTTCTAATGCTTCTGATGCGGCAGATAAATTACGCT
TTAAAGCACTTTCCAACCCTGCTTTATATGAAGGCGATGGCGACTTGCGTGTGCGTGTTAGCTTTGATGCGGATAAAGGC
ACTATCACAATTAGCGATAACGGCATTGGCATGACCCGTGAGCAAGTCATCGATCATTTGGGTACGATTGCAAAATCAGG
AACAAAAGAATTTTTAACCGCACTTGGTCAAGATCAAGCAAAAAATAGCCAGCTTATTGGGCAGTTTGGTGTGGGTTTTT
ATTCTGCTTTTATTGTGGCAGATAAAGTGACTGTAAAAACCAGAGCAGCTGGTGAAGAGGCGGATAAAGCCGTACTTTGG
GAATCTGCGGGTGAAGGCGAATATTCTGTGGCGGATATTGAGAAAAAATCCCGTGGTACAGATGTGATTTTGCATTTACG
TGAAGATGAAAAAGAATTTTTAAATGAATGGCGTTTGCGTGAAATTATTGGTAAATATTCTGACCATATTGGCTTGCCAG
TGGAAATGCTGACGAAAGAATACGATGATGAAGGCAAAGAGTGCGGCGAAAAATGGGAAAAAATCAATAAATCTGATGCC
CTTTGGACGCGTTCTAAAAATGATGTGTCTGATGAGGAATACAAAGCGTTTTACAAACACTTAAGCCATGATTTTGTTGA
TCCTGTGACTTGGGCGCATAACAAAGTTGAGGGAAATCAAGCATATACTAGTTTGCTTTATGTACCAGCTAAAGCACCTT
GGGATTTATTTAATCGAGAACATAAACATGGCTTAAAACTTTATGTTCAACGTGTATTTATTATGGATGATGCTGAGCAA
TTTATACCGAATTATCTACGTTTTATGCGTGGTTTAATCGATAGCAATGACTTGCCATTAAATGTATCTCGTGAAATTTT
ACAGGATAACAAAATTACGGCTGCACTACGCAAAGCATTAACTAAGCGTTCATTACAAATGCTAGAAAAATTAGCAAAAG
ATGATGCAGAAAAATATCTTCAATTCTGGAAAGAGTTTGGTTTAGTCTTAAAAGAAGGCCCTGCAGAAGATTTTGCTAAC
AAAGAAACTGTCGCGAAGTTATTGCGTTTTGCTTCGACACATAATGATGGTAGCGAGCAAACTGTCTCTTTAGAAGATTA
CATCTTGCGTATGAAAGAGGGGCAAAAAGCTATCTATTACATTACAGCGGATAGTTATGTTGCAGCGAAAAATAGCCCGC
ACTTGGAATTATTCAATAAAAAAGGCATTGAGGTTTTGTTGCTTTCCGATCGCATTGATGAATGGATGTTAAGCTATTTA
ACTGAATTCGATGGTAAACAATTACAAAGTATTACAAAAGCAGATTTGGATTTAGGCGATTTAGCGGATAAAGAATCTGA
AACACAAAAACAACAAGATGAAGCCTTTGGTAGTTTTATTGAGCGTGTGAAAAACTTGCTTGGCGAACGTGTGAAAACGG
TGCGTTTAACTCACAATTTAACGGATACACCAGCGGTGGTTTCTACGGATAACGATCAAATGACGACCCAAATGGCGAAA
TTGTTTGCAGCCGCAGGGCAACCTGTACCAGAAGTAAAATACACATTTGAACTGAATCCAGAACACCATTTAGTGAAAAA
AGTGGCTGATATTGCAGATGAAACTGAATTTGCTGATTGGGTGGAATTATTACTTGAACAAGCTATGTTAGCAGAGCGCG
GATCTTTGGAAAATCCAGCTGCGTTTATTAAACGTATCAATAAGTTGTTAGGTTAA

Upstream 100 bases:

>100_bases
GTTTAAATTCCTTGTGTTTTTTTACCGCACTTTTCCTCTTAAATTCCTCTTGAAATCTTTCTTTTTATTCTTATATCTGT
GACGTTCAATTTTTATCTTT

Downstream 100 bases:

>100_bases
TTCATTTGAGATGAAGTAGCATAAGGGTTAAAATCCTCAGTCTGATTAGATTGAGGATTTTTCTTTTTTAGGTGAAATAT
GATTACAGTTTACGGCATTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MKEKIMSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKG
TITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLW
ESAGEGEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDA
LWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQ
FIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFAN
KETVAKLLRFASTHNDGSEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYL
TEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAK
LFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Sequences:

>Translated_631_residues
MKEKIMSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKG
TITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLW
ESAGEGEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDA
LWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQ
FIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFAN
KETVAKLLRFASTHNDGSEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYL
TEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAK
LFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
>Mature_631_residues
MKEKIMSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKG
TITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLW
ESAGEGEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDA
LWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQ
FIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFAN
KETVAKLLRFASTHNDGSEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYL
TEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAK
LFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=680, Percent_Identity=37.5, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI4507677, Length=684, Percent_Identity=35.3801169590643, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI155722983, Length=646, Percent_Identity=36.0681114551084, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=37.3170731707317, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=37.3170731707317, Blast_Score=265, Evalue=9e-71,
Organism=Escherichia coli, GI1786679, Length=623, Percent_Identity=75.2808988764045, Blast_Score=986, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=37.0535714285714, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=671, Percent_Identity=36.0655737704918, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.4876543209877, Blast_Score=326, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=37.0114942528736, Blast_Score=273, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=38.7573964497041, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=38.2352941176471, Blast_Score=452, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=36.8267831149927, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=37.7386196769457, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=646, Percent_Identity=33.7461300309598, Blast_Score=344, Evalue=1e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71766; Mature: 71766

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIMSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNP
CCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ALYEGDGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQA
CEEECCCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCC
KNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGT
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCC
DVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDA
EEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCC
LWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNRE
CEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEEEEEECCCCCHHHHCCH
HKHGLKLYVQRVFIMDDAEQFIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHH
TKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETVAKLLRFASTHNDGSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCC
TVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYL
EEEHHHHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHH
TEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNL
HHCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
TDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADW
CCCCCEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHH
VELLLEQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKEKIMSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNP
CCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
ALYEGDGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQA
CEEECCCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCC
KNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGT
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHCHHHEECCCCCCCEEHHHHHHHCCCC
DVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDA
EEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCC
LWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNRE
CEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHEEEEEEECCCCCHHHHCCH
HKHGLKLYVQRVFIMDDAEQFIPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHH
TKRSLQMLEKLAKDDAEKYLQFWKEFGLVLKEGPAEDFANKETVAKLLRFASTHNDGSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCC
TVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYL
EEEHHHHHHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECHHHHHHHHHHH
TEFDGKQLQSITKADLDLGDLADKESETQKQQDEAFGSFIERVKNLLGERVKTVRLTHNL
HHCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
TDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVADIADETEFADW
CCCCCEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHH
VELLLEQAMLAERGSLENPAAFIKRINKLLG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8972900 [H]