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The map label for this gene is gntP [C]

Identifier: 16272066

GI number: 16272066

Start: 99094

End: 100353

Strand: Reverse

Name: gntP [C]

Synonym: HI0092

Alternate gene names: 16272066

Gene position: 100353-99094 (Counterclockwise)

Preceding gene: 16272067

Following gene: 16272065

Centisome position: 5.48

GC content: 43.41

Gene sequence:

>1260_bases
ATGACAACAGTCTCAGCAATAGGTGCGTTGGTGGCGTTAATCGTTGCTATCTTCCTCATTTTGAAAAAAGTCTCACCAGC
TTATGGTATGTTAGTGGGAGCTTTGGTTGGAGGCTTAATTGGTGGTGCGGATTTATCGCAAACAGTGAGCCTAATGATCG
GTGGCGCACAGGGTATTACTACTGCGGTTATGCGTATCTTAGCTGCTGGTGTGTTGGCCGGTGTGCTGATTGAATCGGGT
GCAGCAAATTCCATCACGGAAACCATTACTAATAAATTGGGTGAAACTCGAGCTTTACTCGCCTTGGCACTAGCGACGAT
GATTTTAACTGCGGTGGGTGTGTTCGTGGATGTGGCAGTGATTACTGTTTCACCAATTGCTTTAGCGTTATCGCGTCGCA
GCGATTTATCGAAAGCTGCAATTTTGCTCGCCATGATTGGCGGTGGTAAAGCTGGTAATATTATGTCGCCAAACCCAAAT
GCCATTGCGGCAGCAGATACTTTTCATTTGCCACTCACTTCCGTGATGATGGCTGGTATAATTCCCGCGCTATTTGGTTT
GATTCTCACCTACTTCTTAGCAAAACGCTTAATCAACAAAGGTTCTAAAGTGACTGACAAAGAGGTAATCGTGCTTGAAA
CGCAAAATTTACCTTCATTTCTGACCGCACTTGTCGCACCTTTAGTGGCAATTTTGCTATTGGCACTTCGTCCATTGTTT
GATATTAAAGTTGATCCATTAATTGCATTGCCGTTAGGTGGTTTGATTGGTGCGTTTTGTATGGGCAAACTTCGCAATAT
AAATAGTTATGCTATCAATGGATTGAGTAAAATGACACCCGTGGCAATTATGTTACTTGGTACAGGCGCGCTTGCTGGCA
TCATTGCTAATTCTGGTTTAAAAGAAGTATTGATTCAAGGTTTGGAACATTCAGGTTTGCCATCATACATTCTTGCACCA
ATTTCAGGGGTGTTGATGTCTTTAGCGACAGCTTCTACCACGGCAGGTACTGCGGTGGCATCCAATGTGTTCAGTAGTAC
CTTGTTAGAACTTGGAGTTAGCAGTCTTGCTGGTGCAGCAATGATTCATGCAGGGGCGACCGTATTTGATCATATGCCAC
ATGGTTCTTTCTTCCATGCCACAGGCGGTAGTGTGAATATGGATATCAAAGAACGTTTAAAACTTATTCCTTATGAAAGT
GCGGTCGGTTTGATGATGACCATCGTTTCTACCTTAATTTTTGGCGTATTTAAATTCTAG

Upstream 100 bases:

>100_bases
TTGATGATTTTTAACCGCACTTTTTGTTTGCTCTAATAAAGCATTTCCCCTATAAAACAGAAATAATCTCCTTGGTTTTA
ATTTTTATAGGAGAGAAAAA

Downstream 100 bases:

>100_bases
GAGTTGTTATGAAATTTGTGATTGCACCTGATTCTTTTAAAGAAAGTTTGACCGCACTTGAAGTCGCTACCGCCATTGAA
ACAGGCTTCAAACGTGTATT

Product: hypothetical protein

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTTVSAIGALVALIVAIFLILKKVSPAYGMLVGALVGGLIGGADLSQTVSLMIGGAQGITTAVMRILAAGVLAGVLIESG
AANSITETITNKLGETRALLALALATMILTAVGVFVDVAVITVSPIALALSRRSDLSKAAILLAMIGGGKAGNIMSPNPN
AIAAADTFHLPLTSVMMAGIIPALFGLILTYFLAKRLINKGSKVTDKEVIVLETQNLPSFLTALVAPLVAILLLALRPLF
DIKVDPLIALPLGGLIGAFCMGKLRNINSYAINGLSKMTPVAIMLLGTGALAGIIANSGLKEVLIQGLEHSGLPSYILAP
ISGVLMSLATASTTAGTAVASNVFSSTLLELGVSSLAGAAMIHAGATVFDHMPHGSFFHATGGSVNMDIKERLKLIPYES
AVGLMMTIVSTLIFGVFKF

Sequences:

>Translated_419_residues
MTTVSAIGALVALIVAIFLILKKVSPAYGMLVGALVGGLIGGADLSQTVSLMIGGAQGITTAVMRILAAGVLAGVLIESG
AANSITETITNKLGETRALLALALATMILTAVGVFVDVAVITVSPIALALSRRSDLSKAAILLAMIGGGKAGNIMSPNPN
AIAAADTFHLPLTSVMMAGIIPALFGLILTYFLAKRLINKGSKVTDKEVIVLETQNLPSFLTALVAPLVAILLLALRPLF
DIKVDPLIALPLGGLIGAFCMGKLRNINSYAINGLSKMTPVAIMLLGTGALAGIIANSGLKEVLIQGLEHSGLPSYILAP
ISGVLMSLATASTTAGTAVASNVFSSTLLELGVSSLAGAAMIHAGATVFDHMPHGSFFHATGGSVNMDIKERLKLIPYES
AVGLMMTIVSTLIFGVFKF
>Mature_418_residues
TTVSAIGALVALIVAIFLILKKVSPAYGMLVGALVGGLIGGADLSQTVSLMIGGAQGITTAVMRILAAGVLAGVLIESGA
ANSITETITNKLGETRALLALALATMILTAVGVFVDVAVITVSPIALALSRRSDLSKAAILLAMIGGGKAGNIMSPNPNA
IAAADTFHLPLTSVMMAGIIPALFGLILTYFLAKRLINKGSKVTDKEVIVLETQNLPSFLTALVAPLVAILLLALRPLFD
IKVDPLIALPLGGLIGAFCMGKLRNINSYAINGLSKMTPVAIMLLGTGALAGIIANSGLKEVLIQGLEHSGLPSYILAPI
SGVLMSLATASTTAGTAVASNVFSSTLLELGVSSLAGAAMIHAGATVFDHMPHGSFFHATGGSVNMDIKERLKLIPYESA
VGLMMTIVSTLIFGVFKF

Specific function: High-Affinity Gluconate Transporter With Fairly Broad Specificity, Including Low Affinity For Glucuronate, Several Disaccharides, And Some Hexoses, But Not Glucose. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family

Homologues:

Organism=Escherichia coli, GI1790776, Length=428, Percent_Identity=23.3644859813084, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y092_HAEIN (Q57493)

Other databases:

- EMBL:   L42023
- PIR:   D64142
- RefSeq:   NP_438265.1
- GeneID:   950987
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0092
- NMPDR:   fig|71421.1.peg.91
- TIGR:   HI_0092
- HOGENOM:   HBG296633
- OMA:   IPYETAV
- ProtClustDB:   CLSK2752803
- BioCyc:   HINF71421:HI_0092-MONOMER
- InterPro:   IPR003474

Pfam domain/function: PF02447 GntP_permease

EC number: NA

Molecular weight: Translated: 42782; Mature: 42651

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb597b54)-; HASH(0x405b55b4)-; HASH(0xbf3434c)-; HASH(0x405af6e0)-; HASH(0xbf0ff2c)-; HASH(0xbfbb764)-; HASH(0xbed31c4)-; HASH(0xb56d07c)-; HASH(0xbcf4dd8)-; HASH(0xb6576d0)-; HASH(0xbe199bc)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVSAIGALVALIVAIFLILKKVSPAYGMLVGALVGGLIGGADLSQTVSLMIGGAQGIT
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
TAVMRILAAGVLAGVLIESGAANSITETITNKLGETRALLALALATMILTAVGVFVDVAV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVSPIALALSRRSDLSKAAILLAMIGGGKAGNIMSPNPNAIAAADTFHLPLTSVMMAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHH
IPALFGLILTYFLAKRLINKGSKVTDKEVIVLETQNLPSFLTALVAPLVAILLLALRPLF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DIKVDPLIALPLGGLIGAFCMGKLRNINSYAINGLSKMTPVAIMLLGTGALAGIIANSGL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
KEVLIQGLEHSGLPSYILAPISGVLMSLATASTTAGTAVASNVFSSTLLELGVSSLAGAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIHAGATVFDHMPHGSFFHATGGSVNMDIKERLKLIPYESAVGLMMTIVSTLIFGVFKF
HHHHCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TTVSAIGALVALIVAIFLILKKVSPAYGMLVGALVGGLIGGADLSQTVSLMIGGAQGIT
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
TAVMRILAAGVLAGVLIESGAANSITETITNKLGETRALLALALATMILTAVGVFVDVAV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVSPIALALSRRSDLSKAAILLAMIGGGKAGNIMSPNPNAIAAADTFHLPLTSVMMAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHH
IPALFGLILTYFLAKRLINKGSKVTDKEVIVLETQNLPSFLTALVAPLVAILLLALRPLF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DIKVDPLIALPLGGLIGAFCMGKLRNINSYAINGLSKMTPVAIMLLGTGALAGIIANSGL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCH
KEVLIQGLEHSGLPSYILAPISGVLMSLATASTTAGTAVASNVFSSTLLELGVSSLAGAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIHAGATVFDHMPHGSFFHATGGSVNMDIKERLKLIPYESAVGLMMTIVSTLIFGVFKF
HHHHCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800