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The map label for this gene is recU [H]

Identifier: 162447691

GI number: 162447691

Start: 867923

End: 868486

Strand: Direct

Name: recU [H]

Synonym: ACL_0833

Alternate gene names: 162447691

Gene position: 867923-868486 (Clockwise)

Preceding gene: 162447689

Following gene: 162447693

Centisome position: 57.98

GC content: 29.26

Gene sequence:

>564_bases
ATGAACTACCCAAATAAAAAAAAGCCAATCAAAAATGTTAATAATTACGCTAACCTTGGAATGACTTTAGAATCCGATAT
AGATTTAACTAATCAGTATTATTTATCTCATCAAATTGCTGTAATTCATAAAAAACCTACGCCTATTCAAGTTGTTAATG
TCAGCTATCCTGCTCGTAATAAAGCTAAAATTGTTGAAGCTTACTACAGAACACCTTCTACTACCGATTTTAATGGTTTA
TATAAAGGACGTTATATTGATTTTGATGCCAAAGAAACAAATTCTAAAACAAGTTTCCCATTATCCAATGTACATGAGCA
TCAAGTTAATCATTTATCTGATGTTGATGCTCATGGTGGTATTGCTTTTTTAATCATTGGATGGTCTCAATATAATGAGT
ATTACATTTTATTTTTCAAAGATCTCATATCTTTTTGGCAAGCATCAAAACAAGGTGGTAGAAAATCAATTCCTTATACT
TTCTTCAAGGAAAATTGTCACCAAATACCATTTAGTTATGAACCACGTCTTGATTATCTTAGCATTATAAATAAATTAAT
TTGA

Upstream 100 bases:

>100_bases
ATATTTTTTCGGACTCTGCTTAAAAAACATAAATTTTATCTTTATCATGTAAATATATCTTAATTAGTTTATAATAACTT
TATATAGGAGATTATGCAAA

Downstream 100 bases:

>100_bases
TCCAAACTGTAGTTTTAATTCTTTAAACTGAGGTAGTGCTAAACTACCAATAATAATGATACTTAATGCAGTGGTTAAGG
TATAGATGATATTATATATA

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNYPNKKKPIKNVNNYANLGMTLESDIDLTNQYYLSHQIAVIHKKPTPIQVVNVSYPARNKAKIVEAYYRTPSTTDFNGL
YKGRYIDFDAKETNSKTSFPLSNVHEHQVNHLSDVDAHGGIAFLIIGWSQYNEYYILFFKDLISFWQASKQGGRKSIPYT
FFKENCHQIPFSYEPRLDYLSIINKLI

Sequences:

>Translated_187_residues
MNYPNKKKPIKNVNNYANLGMTLESDIDLTNQYYLSHQIAVIHKKPTPIQVVNVSYPARNKAKIVEAYYRTPSTTDFNGL
YKGRYIDFDAKETNSKTSFPLSNVHEHQVNHLSDVDAHGGIAFLIIGWSQYNEYYILFFKDLISFWQASKQGGRKSIPYT
FFKENCHQIPFSYEPRLDYLSIINKLI
>Mature_187_residues
MNYPNKKKPIKNVNNYANLGMTLESDIDLTNQYYLSHQIAVIHKKPTPIQVVNVSYPARNKAKIVEAYYRTPSTTDFNGL
YKGRYIDFDAKETNSKTSFPLSNVHEHQVNHLSDVDAHGGIAFLIIGWSQYNEYYILFFKDLISFWQASKQGGRKSIPYT
FFKENCHQIPFSYEPRLDYLSIINKLI

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:
GO:0000287: Holliday junction resolvase recU
GO:0004518: Holliday junction resolvase recU
GO:0004519: Holliday junction resolvase recU
GO:0005737: Holliday junction resolvase recU
GO:0006281: Holliday junction resolvase recU
GO:0006310: Holliday junction resolvase recU
GO:0006974: Holliday junction resolvase recU
GO:0007059: Holliday junction resolvase recU
GO:0016787: Holliday junction resolvase recU
GO:0046872: Holliday junction resolvase recU

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004612
- InterPro:   IPR011335 [H]

Pfam domain/function: PF03838 RecU [H]

EC number: NA

Molecular weight: Translated: 21741; Mature: 21741

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPNKKKPIKNVNNYANLGMTLESDIDLTNQYYLSHQIAVIHKKPTPIQVVNVSYPARN
CCCCCCCCCHHHCCCHHHCCEEEECCCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCC
KAKIVEAYYRTPSTTDFNGLYKGRYIDFDAKETNSKTSFPLSNVHEHQVNHLSDVDAHGG
HHHHHHHHHCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
IAFLIIGWSQYNEYYILFFKDLISFWQASKQGGRKSIPYTFFKENCHQIPFSYEPRLDYL
EEEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEECCCHHCCCCCCCCCHHHH
SIINKLI
HHHHHHC
>Mature Secondary Structure
MNYPNKKKPIKNVNNYANLGMTLESDIDLTNQYYLSHQIAVIHKKPTPIQVVNVSYPARN
CCCCCCCCCHHHCCCHHHCCEEEECCCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCC
KAKIVEAYYRTPSTTDFNGLYKGRYIDFDAKETNSKTSFPLSNVHEHQVNHLSDVDAHGG
HHHHHHHHHCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
IAFLIIGWSQYNEYYILFFKDLISFWQASKQGGRKSIPYTFFKENCHQIPFSYEPRLDYL
EEEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEECCCHHCCCCCCCCCHHHH
SIINKLI
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]