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The map label for this gene is rnc [H]

Identifier: 162447497

GI number: 162447497

Start: 662725

End: 663732

Strand: Direct

Name: rnc [H]

Synonym: ACL_0637

Alternate gene names: 162447497

Gene position: 662725-663732 (Clockwise)

Preceding gene: 162447496

Following gene: 162447498

Centisome position: 44.27

GC content: 28.27

Gene sequence:

>1008_bases
ATGAAAGAAAAAGACATTAAAGAAATAGAAGATATTTTAGGCTATACTTTTACAAATAAAAATTTATTAATTCAAGCCTT
TACTCGAAGTTCTGAAAGAGAAAAAAATAACAATCGCGATTCTGAGATATTAGAGTTCATCGGAGATACTGTAATTAATT
ATGTAATTATTCAAATGTTTAATAATAATTTGTTTAATGCAGATAATTACGGATTGAATTCTCAATATTCTGAGGGTGAG
TTGACAGAATTAAAAAGCTTAATAGTAGAAAATAAAAATTTAGCCGCAAAAATAGACGATTTTGGTCTTGATCGTTTTTT
AAGATCCGACAACTCAAAACAAATACCTTCATCTTTCAAAAGTGACTTATTAGAAAGCATTGTGGGGGCTATCGCAATCG
ATTCTCATTATGAAGAAAAGGAAATATATGAAATAGTAGATTATTTGTTAATGCCTCGTGCTTATATAGGGTCCTTAAAA
TTTAATTATTATTTAAAATTGAAACAATGGTGTAAAATTAGATGTACTTCATCAAATAAATTAAAAGAAAATGTAGAAGA
AATTAAGAATGATAACAACATACAGTATAAGACAACTTTGCGATTTGGTAACTATGAAGTAAGTGCTATAGATAATAGTA
AAATAGATTCATTGTTTGAAGCTTCCATACTTGCCATGAAAAAAATTACAGATAATAAAGATGAAATAACCATTAAAGAT
TTTTTAGTAGGCTTAGATCAAAATAACGGTTGGAGCTATCTTCAAAAAATCCAAAAATTAGGCTATTGTTCCAACCTTTC
AAAAGAATATAAGAAGAATGAAGATGGAACTTGGAAAGCGACATATATGGTTGACGGTATGCGAACATTGTACACTGATA
CCAATAAAAAAAATGCTGGAAATATATGTGCACTAATCTGCATCAACTCTTTAATTGAACCACGTTTCCAAATGGACGAT
AGTATCTTGGAGCTTTTAAGAAAATTAAATTATAAAGAAACGGCTTGA

Upstream 100 bases:

>100_bases
AAAATAGGTCTTCGTAAAGGCATAGTATCGAAGTGGTAGCAACAGAAGTGCTCAAAGAGTTTTATCTACTTCCAGAAAGT
TATGGAAAGGCGGTTGAAAA

Downstream 100 bases:

>100_bases
GCCACTTGTTAAGCCGAAAATTAGGGGTGCGTAAATTTTAATAGGGGTGCGCAAATTTTAGTAGGGGTGCGTAATTGTAT
TAAAATAGGTCACCCAACAC

Product: dsRNA-spesific ribonuclease

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKEKDIKEIEDILGYTFTNKNLLIQAFTRSSEREKNNNRDSEILEFIGDTVINYVIIQMFNNNLFNADNYGLNSQYSEGE
LTELKSLIVENKNLAAKIDDFGLDRFLRSDNSKQIPSSFKSDLLESIVGAIAIDSHYEEKEIYEIVDYLLMPRAYIGSLK
FNYYLKLKQWCKIRCTSSNKLKENVEEIKNDNNIQYKTTLRFGNYEVSAIDNSKIDSLFEASILAMKKITDNKDEITIKD
FLVGLDQNNGWSYLQKIQKLGYCSNLSKEYKKNEDGTWKATYMVDGMRTLYTDTNKKNAGNICALICINSLIEPRFQMDD
SILELLRKLNYKETA

Sequences:

>Translated_335_residues
MKEKDIKEIEDILGYTFTNKNLLIQAFTRSSEREKNNNRDSEILEFIGDTVINYVIIQMFNNNLFNADNYGLNSQYSEGE
LTELKSLIVENKNLAAKIDDFGLDRFLRSDNSKQIPSSFKSDLLESIVGAIAIDSHYEEKEIYEIVDYLLMPRAYIGSLK
FNYYLKLKQWCKIRCTSSNKLKENVEEIKNDNNIQYKTTLRFGNYEVSAIDNSKIDSLFEASILAMKKITDNKDEITIKD
FLVGLDQNNGWSYLQKIQKLGYCSNLSKEYKKNEDGTWKATYMVDGMRTLYTDTNKKNAGNICALICINSLIEPRFQMDD
SILELLRKLNYKETA
>Mature_335_residues
MKEKDIKEIEDILGYTFTNKNLLIQAFTRSSEREKNNNRDSEILEFIGDTVINYVIIQMFNNNLFNADNYGLNSQYSEGE
LTELKSLIVENKNLAAKIDDFGLDRFLRSDNSKQIPSSFKSDLLESIVGAIAIDSHYEEKEIYEIVDYLLMPRAYIGSLK
FNYYLKLKQWCKIRCTSSNKLKENVEEIKNDNNIQYKTTLRFGNYEVSAIDNSKIDSLFEASILAMKKITDNKDEITIKD
FLVGLDQNNGWSYLQKIQKLGYCSNLSKEYKKNEDGTWKATYMVDGMRTLYTDTNKKNAGNICALICINSLIEPRFQMDD
SILELLRKLNYKETA

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=135, Percent_Identity=28.8888888888889, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 38837; Mature: 38837

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKDIKEIEDILGYTFTNKNLLIQAFTRSSEREKNNNRDSEILEFIGDTVINYVIIQMF
CCCCHHHHHHHHHCEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
NNNLFNADNYGLNSQYSEGELTELKSLIVENKNLAAKIDDFGLDRFLRSDNSKQIPSSFK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCCCHHHHH
SDLLESIVGAIAIDSHYEEKEIYEIVDYLLMPRAYIGSLKFNYYLKLKQWCKIRCTSSNK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEEEECCCEEEEECCCHH
LKENVEEIKNDNNIQYKTTLRFGNYEVSAIDNSKIDSLFEASILAMKKITDNKDEITIKD
HHHHHHHHCCCCCEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEHHH
FLVGLDQNNGWSYLQKIQKLGYCSNLSKEYKKNEDGTWKATYMVDGMRTLYTDTNKKNAG
HHEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCCCCCC
NICALICINSLIEPRFQMDDSILELLRKLNYKETA
CCHHHHHHHHHHCCHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKEKDIKEIEDILGYTFTNKNLLIQAFTRSSEREKNNNRDSEILEFIGDTVINYVIIQMF
CCCCHHHHHHHHHCEEECCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
NNNLFNADNYGLNSQYSEGELTELKSLIVENKNLAAKIDDFGLDRFLRSDNSKQIPSSFK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCCCHHHHH
SDLLESIVGAIAIDSHYEEKEIYEIVDYLLMPRAYIGSLKFNYYLKLKQWCKIRCTSSNK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEEEECCCEEEEECCCHH
LKENVEEIKNDNNIQYKTTLRFGNYEVSAIDNSKIDSLFEASILAMKKITDNKDEITIKD
HHHHHHHHCCCCCEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEHHH
FLVGLDQNNGWSYLQKIQKLGYCSNLSKEYKKNEDGTWKATYMVDGMRTLYTDTNKKNAG
HHEECCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHCCCCCCCCC
NICALICINSLIEPRFQMDDSILELLRKLNYKETA
CCHHHHHHHHHHCCHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA