Click here to switch to the map view.

The map label for this gene is mraW1

Identifier: 162447417

GI number: 162447417

Start: 590536

End: 591435

Strand: Direct

Name: mraW1

Synonym: ACL_0555

Alternate gene names: 162447417

Gene position: 590536-591435 (Clockwise)

Preceding gene: 162447416

Following gene: 162447419

Centisome position: 39.45

GC content: 32.78

Gene sequence:

>900_bases
ATGAAACATATCAGTGTATTATTAAATGAATCGATAGAAGGTCTAAACATCAAACCAAACGGTATCTATGTAGATGCTAC
TTTAGGTGGTGGTGGACACTCCCTAGAAATATTAAAAAAACTTGATAAAGGGCACTTATATGCTTTTGATCAAGATGCTT
ATGCAATTGGTAGAGCAACCGAAAGATTAAAAGACTTTAGCAATAAAACATTTATTCAATCAAATTTTTCATTTATAAAA
GAAAAATTAAATGAACTGGGCATATATCAAGTAGATGGTATTATTTTTGACCTTGGTTTATCCTCATTTCAAATTGATGA
TGAAACTAGAGGGTTTTCATATCTTAAAGACTATGATTTAGACATGCGTATGAACAAGGATGCAACCCTAACAGCTAAAG
AAATCGTAAACACTTATGAAAGACAAAAACTAGCAGATATCTTTAGAGCTTATGGTGATGAAGAAAATGCCTGGAAAATT
GCAGGCATGATTGTAGATAGAAGACCACTAAACACAACATTAGAATTAGTTGAGATAACAGATATTGCTAATAAAGGCAT
GAAAGGGCACTCTGCTAAGCGTGTTTTCCAGGCTTTGAGAATCGAGGTCAACAAGGAGTTAGAAGTACTTGAAAGAGCCT
TGAATAGCGCCTTAGAACTCCTTAATATCGGTGGTAGATTATCCATCATTACCTTCCAATCACTAGAAGATAAAATGGTA
AAATCTTTTTATAAAACACATAGTCAAATGGATTACCCTAAAAACATAGATATTAGAACATTTCCAAAGCCACCTTTAAA
AATTATTACAAGAAAACCGGTACTACCTTCAGAAATAGAACTAGAACATAATTCTAGAAGTCGTTCTGCTAAATTAAGAA
TCGCTGAAAAGCAAAGCTAA

Upstream 100 bases:

>100_bases
TTAGCTAAAAAAGTTAAGAAAGAAGATTAACCTTTATTAAGAAAAAGCACGAGAAGTGCTTTTTTCTTTGATATAATATA
TACAAGATGAGGTAAGTTAT

Downstream 100 bases:

>100_bases
ATAAAAAACCTCGAAAAAATCGAGGTTTTATTTATGTTTATGTTTAGAGGGACTTGCAGAAACTAAGATTCTGATATATT
CAATATCATAGTGTTTAAAT

Product: S-adenosylmethionine-dependent methyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase 1; rRNA (cytosine-N(4)-)-methyltransferase RsmH 1

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKHISVLLNESIEGLNIKPNGIYVDATLGGGGHSLEILKKLDKGHLYAFDQDAYAIGRATERLKDFSNKTFIQSNFSFIK
EKLNELGIYQVDGIIFDLGLSSFQIDDETRGFSYLKDYDLDMRMNKDATLTAKEIVNTYERQKLADIFRAYGDEENAWKI
AGMIVDRRPLNTTLELVEITDIANKGMKGHSAKRVFQALRIEVNKELEVLERALNSALELLNIGGRLSIITFQSLEDKMV
KSFYKTHSQMDYPKNIDIRTFPKPPLKIITRKPVLPSEIELEHNSRSRSAKLRIAEKQS

Sequences:

>Translated_299_residues
MKHISVLLNESIEGLNIKPNGIYVDATLGGGGHSLEILKKLDKGHLYAFDQDAYAIGRATERLKDFSNKTFIQSNFSFIK
EKLNELGIYQVDGIIFDLGLSSFQIDDETRGFSYLKDYDLDMRMNKDATLTAKEIVNTYERQKLADIFRAYGDEENAWKI
AGMIVDRRPLNTTLELVEITDIANKGMKGHSAKRVFQALRIEVNKELEVLERALNSALELLNIGGRLSIITFQSLEDKMV
KSFYKTHSQMDYPKNIDIRTFPKPPLKIITRKPVLPSEIELEHNSRSRSAKLRIAEKQS
>Mature_299_residues
MKHISVLLNESIEGLNIKPNGIYVDATLGGGGHSLEILKKLDKGHLYAFDQDAYAIGRATERLKDFSNKTFIQSNFSFIK
EKLNELGIYQVDGIIFDLGLSSFQIDDETRGFSYLKDYDLDMRMNKDATLTAKEIVNTYERQKLADIFRAYGDEENAWKI
AGMIVDRRPLNTTLELVEITDIANKGMKGHSAKRVFQALRIEVNKELEVLERALNSALELLNIGGRLSIITFQSLEDKMV
KSFYKTHSQMDYPKNIDIRTFPKPPLKIITRKPVLPSEIELEHNSRSRSAKLRIAEKQS

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=340, Percent_Identity=35.2941176470588, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI165377202, Length=189, Percent_Identity=38.6243386243386, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1786270, Length=316, Percent_Identity=41.4556962025316, Blast_Score=212, Evalue=2e-56,
Organism=Drosophila melanogaster, GI62472493, Length=330, Percent_Identity=35.4545454545455, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28571637, Length=330, Percent_Identity=35.4545454545455, Blast_Score=171, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH1_ACHLI (A9NFP3)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620549.1
- ProteinModelPortal:   A9NFP3
- SMR:   A9NFP3
- GeneID:   5803253
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0555
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- BioCyc:   ALAI441768:ACL_0555-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34091; Mature: 34091

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: BINDING 50-50 BINDING 76-76 BINDING 97-97 BINDING 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHISVLLNESIEGLNIKPNGIYVDATLGGGGHSLEILKKLDKGHLYAFDQDAYAIGRAT
CCCEEEEECCCCCCCEECCCCEEEEEEECCCCCHHHHHHHCCCCCEEEECCCHHHHHHHH
ERLKDFSNKTFIQSNFSFIKEKLNELGIYQVDGIIFDLGLSSFQIDDETRGFSYLKDYDL
HHHHHCCCCEEEHHHHHHHHHHHHHCCCEEECCEEEECCCCCEEECCCCCCCHHHHCCCC
DMRMNKDATLTAKEIVNTYERQKLADIFRAYGDEENAWKIAGMIVDRRPLNTTLELVEIT
CEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEHEEEH
DIANKGMKGHSAKRVFQALRIEVNKELEVLERALNSALELLNIGGRLSIITFQSLEDKMV
HHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
KSFYKTHSQMDYPKNIDIRTFPKPPLKIITRKPVLPSEIELEHNSRSRSAKLRIAEKQS
HHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCCCCEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKHISVLLNESIEGLNIKPNGIYVDATLGGGGHSLEILKKLDKGHLYAFDQDAYAIGRAT
CCCEEEEECCCCCCCEECCCCEEEEEEECCCCCHHHHHHHCCCCCEEEECCCHHHHHHHH
ERLKDFSNKTFIQSNFSFIKEKLNELGIYQVDGIIFDLGLSSFQIDDETRGFSYLKDYDL
HHHHHCCCCEEEHHHHHHHHHHHHHCCCEEECCEEEECCCCCEEECCCCCCCHHHHCCCC
DMRMNKDATLTAKEIVNTYERQKLADIFRAYGDEENAWKIAGMIVDRRPLNTTLELVEIT
CEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEHEEEH
DIANKGMKGHSAKRVFQALRIEVNKELEVLERALNSALELLNIGGRLSIITFQSLEDKMV
HHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
KSFYKTHSQMDYPKNIDIRTFPKPPLKIITRKPVLPSEIELEHNSRSRSAKLRIAEKQS
HHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCCCCEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA