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The map label for this gene is fabH2 [H]

Identifier: 162447367

GI number: 162447367

Start: 528874

End: 529908

Strand: Direct

Name: fabH2 [H]

Synonym: ACL_0505

Alternate gene names: 162447367

Gene position: 528874-529908 (Clockwise)

Preceding gene: 162447366

Following gene: 162447368

Centisome position: 35.33

GC content: 34.11

Gene sequence:

>1035_bases
ATGAAAGATCACGTTGGAATCGTTGGAACAGGGATTTATTTACCTAAAGAAAGAATGACTGCTAAAGAAATTTCTGAAAA
AACAAATGGTGTTTGGACAGAAGAGGCAGTTATCGAAAAATTAGGTATTAAAACAAAAGTAGTACCTTCATCAAGCTTAA
GCGATGGCACCCAGGAAATGGGTGCTTTAGCCGCACTTGATGCACTAAAAAACACTGGGATTGATCCACTTGATATCGAT
ATCATTTTAAGTGTTTCTGAAGAATGGAAAGAATATCCACTTACAACATCTGCATTATATGTACAAGATAGAATAGGTGC
TATAAATGCTTGGGGAATTGATGTTCAAAACAGATGCTGTACAACAGTTTCTGCACTTAAAATGGCAAAAGACATGTTAC
TTGCTGACCCAGAAGTAAATGTTGTTATGGTAGTTGGTGGTTACCGTAATGGTGACTTTGTCGATTACTCAGATAAAAAT
ATGTCTATGATGTTTAATCTAGGTGCTGGTGGTGGTGCAATCATCTTAAAGAAAAACTATGGCAAAAACCTACTTTTAGG
TAGCCATATGATTTCTGATGGTTCATTATCACGTACAGCTGGTGTTGAAATTGGTGGTATAATAAACCCAATAACTAAGG
AAAATATGGATGAAGCAAAACATTCATTAAGACTACTAGATCCAGTTAAAATGAAAAATAGACTAAACGATGTATCTATG
CCAAATTGGTATAAATGTATCGATGAATCCTTAAGAAAATCTAATCTTGAAAGAAAAGACATTGATTTCTTAAATATTTT
ACATATCAAGCGTAGCGGACATTTATCTATGTTAAATGACTTAGGTTTAACTGAAGACCAAACGATTTACTTAGAAGATT
ACGGTCATATCGGACAAATTGATCAAATACTAACTCTTCATTTAGCTTTAGAACAAGGTAAAGTTAAAGATGGTACAGTT
ATGGCTATGATTGCAGCTGGTATTGGTTATGTATGGGCAGCAAATATTATTCAATGGGGACCAATGAAATCCTAA

Upstream 100 bases:

>100_bases
TAGCATTATTCCTAGCAAGTGATGATGCATCTTACGTAACTGGTCAAACGATTAACGTTAACGGCGGCATGAGACTATAA
TTAAACAAGAGGTGAAGGAC

Downstream 100 bases:

>100_bases
TAAAAAGGAGATGTATACTATGTACAAAGACAAGTTAATCACTGCAAAAGAAGCTGTGAAACTTATCAAATCTAATGATC
ATATTGTAGTTGGGATGACG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKDHVGIVGTGIYLPKERMTAKEISEKTNGVWTEEAVIEKLGIKTKVVPSSSLSDGTQEMGALAALDALKNTGIDPLDID
IILSVSEEWKEYPLTTSALYVQDRIGAINAWGIDVQNRCCTTVSALKMAKDMLLADPEVNVVMVVGGYRNGDFVDYSDKN
MSMMFNLGAGGGAIILKKNYGKNLLLGSHMISDGSLSRTAGVEIGGIINPITKENMDEAKHSLRLLDPVKMKNRLNDVSM
PNWYKCIDESLRKSNLERKDIDFLNILHIKRSGHLSMLNDLGLTEDQTIYLEDYGHIGQIDQILTLHLALEQGKVKDGTV
MAMIAAGIGYVWAANIIQWGPMKS

Sequences:

>Translated_344_residues
MKDHVGIVGTGIYLPKERMTAKEISEKTNGVWTEEAVIEKLGIKTKVVPSSSLSDGTQEMGALAALDALKNTGIDPLDID
IILSVSEEWKEYPLTTSALYVQDRIGAINAWGIDVQNRCCTTVSALKMAKDMLLADPEVNVVMVVGGYRNGDFVDYSDKN
MSMMFNLGAGGGAIILKKNYGKNLLLGSHMISDGSLSRTAGVEIGGIINPITKENMDEAKHSLRLLDPVKMKNRLNDVSM
PNWYKCIDESLRKSNLERKDIDFLNILHIKRSGHLSMLNDLGLTEDQTIYLEDYGHIGQIDQILTLHLALEQGKVKDGTV
MAMIAAGIGYVWAANIIQWGPMKS
>Mature_344_residues
MKDHVGIVGTGIYLPKERMTAKEISEKTNGVWTEEAVIEKLGIKTKVVPSSSLSDGTQEMGALAALDALKNTGIDPLDID
IILSVSEEWKEYPLTTSALYVQDRIGAINAWGIDVQNRCCTTVSALKMAKDMLLADPEVNVVMVVGGYRNGDFVDYSDKN
MSMMFNLGAGGGAIILKKNYGKNLLLGSHMISDGSLSRTAGVEIGGIINPITKENMDEAKHSLRLLDPVKMKNRLNDVSM
PNWYKCIDESLRKSNLERKDIDFLNILHIKRSGHLSMLNDLGLTEDQTIYLEDYGHIGQIDQILTLHLALEQGKVKDGTV
MAMIAAGIGYVWAANIIQWGPMKS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:
GO:0003824: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0004315: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0005737: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0006633: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0008152: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0008610: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0016740: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0016746: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0016747: 3-oxoacyl-[acyl-carrier-protein] synthase III
GO:0033818: 3-oxoacyl-[acyl-carrier-protein] synthase III

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=340, Percent_Identity=22.6470588235294, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37787; Mature: 37787

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDHVGIVGTGIYLPKERMTAKEISEKTNGVWTEEAVIEKLGIKTKVVPSSSLSDGTQEM
CCCCCEEEEECEECCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCHHHH
GALAALDALKNTGIDPLDIDIILSVSEEWKEYPLTTSALYVQDRIGAINAWGIDVQNRCC
HHHHHHHHHHHCCCCCEEEEEEEEECHHHHHCCCCCEEEEEECCCCEEEEECCCCCCHHH
TTVSALKMAKDMLLADPEVNVVMVVGGYRNGDFVDYSDKNMSMMFNLGAGGGAIILKKNY
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCEEEEEEECCCCCEEEEEECC
GKNLLLGSHMISDGSLSRTAGVEIGGIINPITKENMDEAKHSLRLLDPVKMKNRLNDVSM
CCEEEEECEECCCCCCCCCCCEEECCCCCCHHHCHHHHHHHHHHHCCHHHHHHHCCCCCC
PNWYKCIDESLRKSNLERKDIDFLNILHIKRSGHLSMLNDLGLTEDQTIYLEDYGHIGQI
CHHHHHHHHHHHHCCCCHHCCCEEEEEEEECCCCCHHHHHCCCCCCCEEEEECCCCCCCH
DQILTLHLALEQGKVKDGTVMAMIAAGIGYVWAANIIQWGPMKS
HHHHEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDHVGIVGTGIYLPKERMTAKEISEKTNGVWTEEAVIEKLGIKTKVVPSSSLSDGTQEM
CCCCCEEEEECEECCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCHHHH
GALAALDALKNTGIDPLDIDIILSVSEEWKEYPLTTSALYVQDRIGAINAWGIDVQNRCC
HHHHHHHHHHHCCCCCEEEEEEEEECHHHHHCCCCCEEEEEECCCCEEEEECCCCCCHHH
TTVSALKMAKDMLLADPEVNVVMVVGGYRNGDFVDYSDKNMSMMFNLGAGGGAIILKKNY
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCEEEEEEECCCCCEEEEEECC
GKNLLLGSHMISDGSLSRTAGVEIGGIINPITKENMDEAKHSLRLLDPVKMKNRLNDVSM
CCEEEEECEECCCCCCCCCCCEEECCCCCCHHHCHHHHHHHHHHHCCHHHHHHHCCCCCC
PNWYKCIDESLRKSNLERKDIDFLNILHIKRSGHLSMLNDLGLTEDQTIYLEDYGHIGQI
CHHHHHHHHHHHHCCCCHHCCCEEEEEEEECCCCCHHHHHCCCCCCCEEEEECCCCCCCH
DQILTLHLALEQGKVKDGTVMAMIAAGIGYVWAANIIQWGPMKS
HHHHEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA