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The map label for this gene is yeeO [C]

Identifier: 162447355

GI number: 162447355

Start: 516246

End: 517664

Strand: Direct

Name: yeeO [C]

Synonym: ACL_0493

Alternate gene names: 162447355

Gene position: 516246-517664 (Clockwise)

Preceding gene: 162447354

Following gene: 162447356

Centisome position: 34.49

GC content: 33.76

Gene sequence:

>1419_bases
ATGGAACAAGGCATTTCAAAAAATACACAACGCATGTTAAACGGGAAGCATATATGGCTATATATGCTCCTTTTATCGTT
ACCGATACTTATTAACAACTTGATCAAGTCTTTTAATGGTATGGTTGATATTTATTTTATCGCTCGCATCAAAGATGTAA
GTACTGAGACGATTGACTCAGCTATAGCTGCATTAAACATTCATGAGTCATTTAATAACCTCATTTTAGCAATTGGTGTT
GGTTTATCGATTGCAGCTATGGCGATTGTATCCCAATTTGTAGGGGCTAAAAGGGAAGATAAAGCAAAATTCTATGCTGG
TCAACTTCTTACAATAGCACTTATTGTTGGGATTGCATTAACGCTTGTAATTCTAGGTTTTTCTTGGTTCTTTATTGATT
TGTTGGGAGCTAAGGGACAAACATTTAATTTTGCTTTAGAATATTTCAATATTCGAAGTCTTGAACTTGTAGGTGTTATA
TTTTTCTTGGTTTATCAAGCGATTAGACAAGCCCAAGGATCAACCATTACACCTACGCTTTTAAATATTGGCGGTATTTT
GGTAAATATAGGTTTTACATGGTATTTTGTTGAAGTGCTTAACTGGGGTGTAGCAGGCTCTGCTTGGGCAACATTAATCG
GTAACTTAATTTTTGTTCCACTGATGATTCTAGATTTATTTATTAGTCGCCGATACATGAGATTAAAATTAAGTGCCTTT
GTACCTAAAAAGAAAACTCTAAAAGAAATATGGCCATTTGCATACCCTGCAACCGTGTCACACTCTGTAACATTTTTAGG
ATTTTTAATTATTAATTCATTCGTTTTAAGTCAGTTTGGAGATGTCATATCGGCATCATTTTCAACCGGTAATAAACTAA
GTAATTTACTTATGAATCCAATTTATGCAATTACCACGATTGGTGCAGTATTTATCGGTGCAAACATCGGTAACAGACAA
CCCGAAAGAGCACTAAAAGTATATAAACAATCTGGTAGAATGACCTTTACAATTACCGTAGTAGCAATTCTTGTAGCTAT
ACTATTTAGAAAAGAATTTGTAACTTTATTAGTAGGTACACAAAATGATCGATTAATTGAAGTATCGGTAGAATATACAT
TATGGTTACTACTAACTCAACCCGTAATGTCGATCTTCCAAAACTATATGGCGATTTTTAATGGAAGTGGACAGTCTAAG
CTTGGACTTAAAGCACAATCATTTAGATTATGGGGATTACGTATTCCACTATTATTTGGTCTATGGTTCTTATTCCCTGA
AATGAAATATAGTGTTGTTTGGACAGCGATGAATATATCCAATGTGATTGCTTTATTCCATGCACACTACTTAAGAAAAA
ACATTGAACTAGATATCAAAGTGAATTTAGAAGATGATGAAAGTGAGGTGCTCGTATGA

Upstream 100 bases:

>100_bases
TTTCCACATGAATACTATGTTGATTTATCACAAGATTTATGGGATTTACGACGAGCATTAGTAGTTAAGCATAAACATTA
GAAAGTAGAACCTGATAATC

Downstream 100 bases:

>100_bases
TACATGTTGTATTATGCCAACCTGAAATTCCTCAAAATACTGGAAATATCATGCGTACATGTGTAGGTAGTGGTGTCCAT
CTGCACTTAATTAAACCCCT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEQGISKNTQRMLNGKHIWLYMLLLSLPILINNLIKSFNGMVDIYFIARIKDVSTETIDSAIAALNIHESFNNLILAIGV
GLSIAAMAIVSQFVGAKREDKAKFYAGQLLTIALIVGIALTLVILGFSWFFIDLLGAKGQTFNFALEYFNIRSLELVGVI
FFLVYQAIRQAQGSTITPTLLNIGGILVNIGFTWYFVEVLNWGVAGSAWATLIGNLIFVPLMILDLFISRRYMRLKLSAF
VPKKKTLKEIWPFAYPATVSHSVTFLGFLIINSFVLSQFGDVISASFSTGNKLSNLLMNPIYAITTIGAVFIGANIGNRQ
PERALKVYKQSGRMTFTITVVAILVAILFRKEFVTLLVGTQNDRLIEVSVEYTLWLLLTQPVMSIFQNYMAIFNGSGQSK
LGLKAQSFRLWGLRIPLLFGLWFLFPEMKYSVVWTAMNISNVIALFHAHYLRKNIELDIKVNLEDDESEVLV

Sequences:

>Translated_472_residues
MEQGISKNTQRMLNGKHIWLYMLLLSLPILINNLIKSFNGMVDIYFIARIKDVSTETIDSAIAALNIHESFNNLILAIGV
GLSIAAMAIVSQFVGAKREDKAKFYAGQLLTIALIVGIALTLVILGFSWFFIDLLGAKGQTFNFALEYFNIRSLELVGVI
FFLVYQAIRQAQGSTITPTLLNIGGILVNIGFTWYFVEVLNWGVAGSAWATLIGNLIFVPLMILDLFISRRYMRLKLSAF
VPKKKTLKEIWPFAYPATVSHSVTFLGFLIINSFVLSQFGDVISASFSTGNKLSNLLMNPIYAITTIGAVFIGANIGNRQ
PERALKVYKQSGRMTFTITVVAILVAILFRKEFVTLLVGTQNDRLIEVSVEYTLWLLLTQPVMSIFQNYMAIFNGSGQSK
LGLKAQSFRLWGLRIPLLFGLWFLFPEMKYSVVWTAMNISNVIALFHAHYLRKNIELDIKVNLEDDESEVLV
>Mature_472_residues
MEQGISKNTQRMLNGKHIWLYMLLLSLPILINNLIKSFNGMVDIYFIARIKDVSTETIDSAIAALNIHESFNNLILAIGV
GLSIAAMAIVSQFVGAKREDKAKFYAGQLLTIALIVGIALTLVILGFSWFFIDLLGAKGQTFNFALEYFNIRSLELVGVI
FFLVYQAIRQAQGSTITPTLLNIGGILVNIGFTWYFVEVLNWGVAGSAWATLIGNLIFVPLMILDLFISRRYMRLKLSAF
VPKKKTLKEIWPFAYPATVSHSVTFLGFLIINSFVLSQFGDVISASFSTGNKLSNLLMNPIYAITTIGAVFIGANIGNRQ
PERALKVYKQSGRMTFTITVVAILVAILFRKEFVTLLVGTQNDRLIEVSVEYTLWLLLTQPVMSIFQNYMAIFNGSGQSK
LGLKAQSFRLWGLRIPLLFGLWFLFPEMKYSVVWTAMNISNVIALFHAHYLRKNIELDIKVNLEDDESEVLV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52922; Mature: 52922

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQGISKNTQRMLNGKHIWLYMLLLSLPILINNLIKSFNGMVDIYFIARIKDVSTETIDS
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHH
AIAALNIHESFNNLILAIGVGLSIAAMAIVSQFVGAKREDKAKFYAGQLLTIALIVGIAL
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TLVILGFSWFFIDLLGAKGQTFNFALEYFNIRSLELVGVIFFLVYQAIRQAQGSTITPTL
HHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LNIGGILVNIGFTWYFVEVLNWGVAGSAWATLIGNLIFVPLMILDLFISRRYMRLKLSAF
HHHCHHHEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHH
VPKKKTLKEIWPFAYPATVSHSVTFLGFLIINSFVLSQFGDVISASFSTGNKLSNLLMNP
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IYAITTIGAVFIGANIGNRQPERALKVYKQSGRMTFTITVVAILVAILFRKEFVTLLVGT
HHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHEEEEC
QNDRLIEVSVEYTLWLLLTQPVMSIFQNYMAIFNGSGQSKLGLKAQSFRLWGLRIPLLFG
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHEEEEEEHHHHHHH
LWFLFPEMKYSVVWTAMNISNVIALFHAHYLRKNIELDIKVNLEDDESEVLV
HHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MEQGISKNTQRMLNGKHIWLYMLLLSLPILINNLIKSFNGMVDIYFIARIKDVSTETIDS
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHH
AIAALNIHESFNNLILAIGVGLSIAAMAIVSQFVGAKREDKAKFYAGQLLTIALIVGIAL
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TLVILGFSWFFIDLLGAKGQTFNFALEYFNIRSLELVGVIFFLVYQAIRQAQGSTITPTL
HHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LNIGGILVNIGFTWYFVEVLNWGVAGSAWATLIGNLIFVPLMILDLFISRRYMRLKLSAF
HHHCHHHEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHH
VPKKKTLKEIWPFAYPATVSHSVTFLGFLIINSFVLSQFGDVISASFSTGNKLSNLLMNP
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IYAITTIGAVFIGANIGNRQPERALKVYKQSGRMTFTITVVAILVAILFRKEFVTLLVGT
HHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHEEEEC
QNDRLIEVSVEYTLWLLLTQPVMSIFQNYMAIFNGSGQSKLGLKAQSFRLWGLRIPLLFG
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHEEEEEEHHHHHHH
LWFLFPEMKYSVVWTAMNISNVIALFHAHYLRKNIELDIKVNLEDDESEVLV
HHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]