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The map label for this gene is arsC [H]

Identifier: 162447352

GI number: 162447352

Start: 513008

End: 513403

Strand: Direct

Name: arsC [H]

Synonym: ACL_0490

Alternate gene names: 162447352

Gene position: 513008-513403 (Clockwise)

Preceding gene: 162447351

Following gene: 162447353

Centisome position: 34.27

GC content: 36.36

Gene sequence:

>396_bases
ATGAAAAAAATCGCATTTGTATGTGTACATAACAGTTGCCGTAGCCAAATGGCTGAAGGGTTTGCAAAAGCATATGGTGA
AGGTATTATCGAAGTATATTCTGCTGGAACTGAAAACTATCCTGAAGTTAAACCACTTGCTGTAGAAGTCATGCATGAAG
TTGGTATAAACCTAGATAGCCAGTACCCTAAACTACTCGATGAAATTCCTATACCTGATATATTAATCACCATGGGATGT
AATGCAAATTGCCCATGGGTACCTAATGATTATCACGAGGATTGGGGTTTGGATGATCCAAGTGGTAAAGGTATTGAAGC
ATTTAGGGTCACCAGAGAACTTATTAAAACTAAAGTAATTGAACTCATAAATCTCGTAAAAAATGAGCAAATATAA

Upstream 100 bases:

>100_bases
ATATACCTTCAATGTAAAATCTTAGTAAAACATGGTGTCAATTATATAAAAATTCAATGTACACATGTTACAATGAAGTT
ATATTGTTAAAGAGGTGTCC

Downstream 100 bases:

>100_bases
CACTATAAATTAATAATTTAAAAAAGTACACAAAAAACTCATGTTTTTTGTGTTTTCCATGTTTTTATTGTATAAAAATG
CTATATTAGTAACGTTAAAA

Product: protein-tyrosine phosphatase, low molecular weight

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKIAFVCVHNSCRSQMAEGFAKAYGEGIIEVYSAGTENYPEVKPLAVEVMHEVGINLDSQYPKLLDEIPIPDILITMGC
NANCPWVPNDYHEDWGLDDPSGKGIEAFRVTRELIKTKVIELINLVKNEQI

Sequences:

>Translated_131_residues
MKKIAFVCVHNSCRSQMAEGFAKAYGEGIIEVYSAGTENYPEVKPLAVEVMHEVGINLDSQYPKLLDEIPIPDILITMGC
NANCPWVPNDYHEDWGLDDPSGKGIEAFRVTRELIKTKVIELINLVKNEQI
>Mature_131_residues
MKKIAFVCVHNSCRSQMAEGFAKAYGEGIIEVYSAGTENYPEVKPLAVEVMHEVGINLDSQYPKLLDEIPIPDILITMGC
NANCPWVPNDYHEDWGLDDPSGKGIEAFRVTRELIKTKVIELINLVKNEQI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 14679; Mature: 14679

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAFVCVHNSCRSQMAEGFAKAYGEGIIEVYSAGTENYPEVKPLAVEVMHEVGINLDS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
QYPKLLDEIPIPDILITMGCNANCPWVPNDYHEDWGLDDPSGKGIEAFRVTRELIKTKVI
CHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ELINLVKNEQI
HHHHHHHCCCC
>Mature Secondary Structure
MKKIAFVCVHNSCRSQMAEGFAKAYGEGIIEVYSAGTENYPEVKPLAVEVMHEVGINLDS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
QYPKLLDEIPIPDILITMGCNANCPWVPNDYHEDWGLDDPSGKGIEAFRVTRELIKTKVI
CHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ELINLVKNEQI
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA