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The map label for this gene is argS [H]

Identifier: 162447348

GI number: 162447348

Start: 508229

End: 509908

Strand: Direct

Name: argS [H]

Synonym: ACL_0485

Alternate gene names: 162447348

Gene position: 508229-509908 (Clockwise)

Preceding gene: 162447346

Following gene: 162447349

Centisome position: 33.95

GC content: 29.88

Gene sequence:

>1680_bases
ATGATATGCATGATAGAGCAAATTAAATTAGAGCTCAGACAATTATTATTTGATCATTTAGATATAGAAGATGTTGTATT
AGAAGTACCTAAAAGGGGCGATTCTGATTTAGCAATTCCATTATTTGGATATCAAAAACAAATGGGTAAAAAATTACCTG
AAATCTTTGACTTATTTAAAGATATATTAATTCAACATCGTTTAGTAGAATCTGTAGTATTTACTGCAGGGTTTTTAAAC
ATCTATCTAAAACGAGTGGATGTATCCAAATCTATTTTAAATTCAATACATGATGAGAAGCAATCCTTTGGTACACAACC
AAATAATAATAAAACTATTGTTATCGACTATTCCTCACCTAATATTGCTAAAAGCTTTAGCGTTGGTCATTTACGTTCAA
CGGTTATCGGTAATAGTTTAAAATTAATTTACCAAAAATTAGGTTATAACGTTGTAGGGATTAATCACCTAGGTGATTGG
GGTACACAATTTGGATCTATGATGGTTGCATACCGTATGTGGGGCGACAAAGATAAAATTAAGGCTAATCCTATTGATGA
GCTTCAAGCACTTTATGTGCGTTTTCACGAGGCAGCTGAAAAAGATGAATCATTAAAACAAAAGGCTCGCGATGCTTTCT
TAAAACTAGAACAAGGGGATCCAGAATACACAAAATTATGGACATATTTTAGAGAAGTATCCCTGCAAGAATTTATGACT
ATGTATGATATTTTAGATGTTAGTTTTGATAGTTATAATGGTGAAGCATTCTATAATGATAAAATGGATAGAGTAGTTAA
AGAATTAGAAGATAAACATTTACTCGTCGAAGATCAAGGTGCGATGGTTGTCAAATTAGAAGATGACACACCACCTGTAC
TAATTAAAAGAAGTGATGGTGCAACACTATATACTACAAGAGATCTAGCAGCACTACTGTATAGAAATGATACATATCAT
TTTGATAAGGCATTATATGTTGTTGGTAATGAACAAAAACTCCATTTTGAAAACTTGAAGAAAGTTGTCAAAATGATGGG
TTATGATTTTAATATTGAACACATTAATTTTGGCCTTGTTTTACAAGATGGTAAAAAGATGTCTACTAGAAAAGGTAAGA
CAACAAAGTTAGACTATGTGTTAAATCAAGCCGTATTAAAAGCAAAACAAGCAATTGAAGAAAAGAATCCCAACTTAGAA
AATAAAGATCAAGTAGCCAAAGTTGTAGGTATTGGTGCTGTTATCTTTAATGACCTTAAAAATGATAGAACTTTAAATAT
TGAATTTGATTTAGATGGTATGCTTAAGTTTGAAGGACAAACTGGGCCATATCTGTTATATTCTATCGTAAGAATTTTCT
CTATTCTAAAATCAAATACAATAGATATTACTCAAGTAGACTATACACTATATCAAGATGAAATCTATTATAGTTTAATT
AAAGTACTTGATCAATTCCCAAGTGTTGTACAAAGAGCAGCAGAAAGTTATTCACCATCTACAGTAGCTAAATATTTATT
ACAATTATCACAAGAATTTAATACATTTTATGCTAAAGTAAAAATTAATGATAGTAATGATGTTGTAAGACAAACAAATC
TATTATTAGTAGAAAGTATTTTAAATATCTTAATCGAGGGTTTAAGACTTCTAGGTATGAAACATTTAGAAGCAATGTAA

Upstream 100 bases:

>100_bases
TTTATTTTATCACAAAAATATAAAATGTCCAAAAAGTATGAAAAAACTAATGGAAAAAAATAATTTATCCTAAAAGTTTG
ATATAATATGATAAATGGAG

Downstream 100 bases:

>100_bases
TATGGAAAATAATAGTAATAATAACAACAATACAAAATCAAATAAATTATGGTTAAATGGAATCGTTGTAGTAGTTATAC
TGTTAACGCTTTTCACTATA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MICMIEQIKLELRQLLFDHLDIEDVVLEVPKRGDSDLAIPLFGYQKQMGKKLPEIFDLFKDILIQHRLVESVVFTAGFLN
IYLKRVDVSKSILNSIHDEKQSFGTQPNNNKTIVIDYSSPNIAKSFSVGHLRSTVIGNSLKLIYQKLGYNVVGINHLGDW
GTQFGSMMVAYRMWGDKDKIKANPIDELQALYVRFHEAAEKDESLKQKARDAFLKLEQGDPEYTKLWTYFREVSLQEFMT
MYDILDVSFDSYNGEAFYNDKMDRVVKELEDKHLLVEDQGAMVVKLEDDTPPVLIKRSDGATLYTTRDLAALLYRNDTYH
FDKALYVVGNEQKLHFENLKKVVKMMGYDFNIEHINFGLVLQDGKKMSTRKGKTTKLDYVLNQAVLKAKQAIEEKNPNLE
NKDQVAKVVGIGAVIFNDLKNDRTLNIEFDLDGMLKFEGQTGPYLLYSIVRIFSILKSNTIDITQVDYTLYQDEIYYSLI
KVLDQFPSVVQRAAESYSPSTVAKYLLQLSQEFNTFYAKVKINDSNDVVRQTNLLLVESILNILIEGLRLLGMKHLEAM

Sequences:

>Translated_559_residues
MICMIEQIKLELRQLLFDHLDIEDVVLEVPKRGDSDLAIPLFGYQKQMGKKLPEIFDLFKDILIQHRLVESVVFTAGFLN
IYLKRVDVSKSILNSIHDEKQSFGTQPNNNKTIVIDYSSPNIAKSFSVGHLRSTVIGNSLKLIYQKLGYNVVGINHLGDW
GTQFGSMMVAYRMWGDKDKIKANPIDELQALYVRFHEAAEKDESLKQKARDAFLKLEQGDPEYTKLWTYFREVSLQEFMT
MYDILDVSFDSYNGEAFYNDKMDRVVKELEDKHLLVEDQGAMVVKLEDDTPPVLIKRSDGATLYTTRDLAALLYRNDTYH
FDKALYVVGNEQKLHFENLKKVVKMMGYDFNIEHINFGLVLQDGKKMSTRKGKTTKLDYVLNQAVLKAKQAIEEKNPNLE
NKDQVAKVVGIGAVIFNDLKNDRTLNIEFDLDGMLKFEGQTGPYLLYSIVRIFSILKSNTIDITQVDYTLYQDEIYYSLI
KVLDQFPSVVQRAAESYSPSTVAKYLLQLSQEFNTFYAKVKINDSNDVVRQTNLLLVESILNILIEGLRLLGMKHLEAM
>Mature_559_residues
MICMIEQIKLELRQLLFDHLDIEDVVLEVPKRGDSDLAIPLFGYQKQMGKKLPEIFDLFKDILIQHRLVESVVFTAGFLN
IYLKRVDVSKSILNSIHDEKQSFGTQPNNNKTIVIDYSSPNIAKSFSVGHLRSTVIGNSLKLIYQKLGYNVVGINHLGDW
GTQFGSMMVAYRMWGDKDKIKANPIDELQALYVRFHEAAEKDESLKQKARDAFLKLEQGDPEYTKLWTYFREVSLQEFMT
MYDILDVSFDSYNGEAFYNDKMDRVVKELEDKHLLVEDQGAMVVKLEDDTPPVLIKRSDGATLYTTRDLAALLYRNDTYH
FDKALYVVGNEQKLHFENLKKVVKMMGYDFNIEHINFGLVLQDGKKMSTRKGKTTKLDYVLNQAVLKAKQAIEEKNPNLE
NKDQVAKVVGIGAVIFNDLKNDRTLNIEFDLDGMLKFEGQTGPYLLYSIVRIFSILKSNTIDITQVDYTLYQDEIYYSLI
KVLDQFPSVVQRAAESYSPSTVAKYLLQLSQEFNTFYAKVKINDSNDVVRQTNLLLVESILNILIEGLRLLGMKHLEAM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:
GO:0000166: Arginyl-tRNA synthetase
GO:0004812: Arginyl-tRNA synthetase
GO:0004814: Arginyl-tRNA synthetase
GO:0005524: Arginyl-tRNA synthetase
GO:0005737: Arginyl-tRNA synthetase
GO:0006412: Arginyl-tRNA synthetase
GO:0006418: Arginyl-tRNA synthetase
GO:0006420: Arginyl-tRNA synthetase
GO:0016874: Arginyl-tRNA synthetase

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=495, Percent_Identity=33.9393939393939, Blast_Score=293, Evalue=4e-79,
Organism=Homo sapiens, GI15149476, Length=525, Percent_Identity=32, Blast_Score=254, Evalue=1e-67,
Organism=Escherichia coli, GI1788184, Length=500, Percent_Identity=33.6, Blast_Score=282, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71985061, Length=538, Percent_Identity=31.7843866171004, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71985068, Length=492, Percent_Identity=33.5365853658537, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17532153, Length=492, Percent_Identity=28.4552845528455, Blast_Score=189, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320548, Length=514, Percent_Identity=34.2412451361868, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6321883, Length=518, Percent_Identity=32.2393822393822, Blast_Score=293, Evalue=5e-80,
Organism=Drosophila melanogaster, GI18859963, Length=515, Percent_Identity=31.8446601941748, Blast_Score=238, Evalue=8e-63,
Organism=Drosophila melanogaster, GI28571570, Length=471, Percent_Identity=33.7579617834395, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64266; Mature: 64266

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICMIEQIKLELRQLLFDHLDIEDVVLEVPKRGDSDLAIPLFGYQKQMGKKLPEIFDLFK
CEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
DILIQHRLVESVVFTAGFLNIYLKRVDVSKSILNSIHDEKQSFGTQPNNNKTIVIDYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
NIAKSFSVGHLRSTVIGNSLKLIYQKLGYNVVGINHLGDWGTQFGSMMVAYRMWGDKDKI
CCHHCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
KANPIDELQALYVRFHEAAEKDESLKQKARDAFLKLEQGDPEYTKLWTYFREVSLQEFMT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
MYDILDVSFDSYNGEAFYNDKMDRVVKELEDKHLLVEDQGAMVVKLEDDTPPVLIKRSDG
HHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCEEEECCCC
ATLYTTRDLAALLYRNDTYHFDKALYVVGNEQKLHFENLKKVVKMMGYDFNIEHINFGLV
CEEEEHHHHHHHHHCCCCEEECCEEEEECCCCEECHHHHHHHHHHHCCCCCEEEEEEEEE
LQDGKKMSTRKGKTTKLDYVLNQAVLKAKQAIEEKNPNLENKDQVAKVVGIGAVIFNDLK
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
NDRTLNIEFDLDGMLKFEGQTGPYLLYSIVRIFSILKSNTIDITQVDYTLYQDEIYYSLI
CCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
KVLDQFPSVVQRAAESYSPSTVAKYLLQLSQEFNTFYAKVKINDSNDVVRQTNLLLVESI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHH
LNILIEGLRLLGMKHLEAM
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MICMIEQIKLELRQLLFDHLDIEDVVLEVPKRGDSDLAIPLFGYQKQMGKKLPEIFDLFK
CEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
DILIQHRLVESVVFTAGFLNIYLKRVDVSKSILNSIHDEKQSFGTQPNNNKTIVIDYSSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
NIAKSFSVGHLRSTVIGNSLKLIYQKLGYNVVGINHLGDWGTQFGSMMVAYRMWGDKDKI
CCHHCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
KANPIDELQALYVRFHEAAEKDESLKQKARDAFLKLEQGDPEYTKLWTYFREVSLQEFMT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
MYDILDVSFDSYNGEAFYNDKMDRVVKELEDKHLLVEDQGAMVVKLEDDTPPVLIKRSDG
HHHHHHCCCCCCCCCEEECHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCEEEECCCC
ATLYTTRDLAALLYRNDTYHFDKALYVVGNEQKLHFENLKKVVKMMGYDFNIEHINFGLV
CEEEEHHHHHHHHHCCCCEEECCEEEEECCCCEECHHHHHHHHHHHCCCCCEEEEEEEEE
LQDGKKMSTRKGKTTKLDYVLNQAVLKAKQAIEEKNPNLENKDQVAKVVGIGAVIFNDLK
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
NDRTLNIEFDLDGMLKFEGQTGPYLLYSIVRIFSILKSNTIDITQVDYTLYQDEIYYSLI
CCEEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
KVLDQFPSVVQRAAESYSPSTVAKYLLQLSQEFNTFYAKVKINDSNDVVRQTNLLLVESI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHH
LNILIEGLRLLGMKHLEAM
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA