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The map label for this gene is accD

Identifier: 162447322

GI number: 162447322

Start: 484900

End: 485778

Strand: Direct

Name: accD

Synonym: ACL_0459

Alternate gene names: 162447322

Gene position: 484900-485778 (Clockwise)

Preceding gene: 162447321

Following gene: 162447323

Centisome position: 32.39

GC content: 34.36

Gene sequence:

>879_bases
ATGAATCACTTATTGGATGAACGTAAAAGAAGATTATCTCAGTTTCATGAGATTATTAAAAAAAGACCTATAGAAACTAG
GCCAGTAGATATTCCTGATGGTGTATTTAGTCAGTGTGAACAATGTAACTCTGCAATCTATAATAAGGATTTAGAACATA
ACTATGAAGTATGTCCTTATTGTAGTTACCATTTTAAAATTAATGCGGTAAAGCGTTTAAAGTATACACTTGATGAGGAT
ACTTTTAAACCTTTATTTGAGAACATAACATCCAAAAATCCTCTAGGCATGCCTGAATATGAAGAAAAGTTAGATAAAGG
TATGAGAATGGCAAAAATGAATGAAGCATTTTTAGCAGGAACTGGGAAAATAGATGGTCAAAACTTGGCTATCGGTGTTC
TTGATTCATATTTTATGATGGGTTCAATGGGTTCAGTTGTAGGGGAGCGTATCACTAGATTAATTGAACATGCTGCTAAG
CACAATCTACCGCTTGTTATATTTAGTGCATCCGGTGGAGCACGTATGCAAGAAGGTATTTTAAGTTTAATGCAAATGGC
TAAAACATCTGGTGCTTTAAATTTGCTTGATGAAAAAGGCTTAGTATACATTTCTGTAATGACGAATCCAACAACCGGTG
GTGTTGCTGCATCCTTTGCAAGTTTAGGGGATATCAATATTGCTGAAAAATCCAGTTTAATTGGTTTCGCAGGTGCTAGA
GTTATTAAACAAACAATTGGTCAAGATTTACCAGCTGGTTTTCAAACCGATGCTTTTCAACTTCAAAAAGGACAAGTGGA
CTTGGTTGTTTTAAGATCTCAATTGAAAAAGACTTTATCAACATTACTTAAACTACATGCTAAGAAGGTGACATCATGA

Upstream 100 bases:

>100_bases
GAATATCATTATGCAATATTACATGCTACTGATTTTATTAAAGGTACATATGATACAGGATTTGTAGCTAAATTTAATGG
ATTAATCCAAGGTGAATATA

Downstream 100 bases:

>100_bases
CAGATATGGATAAAGTTTGGCAAAGAGTTAAGTTGGCACGTAGTGCTGATAGGCCAACATCAAAGTCACTTATTAAAGCA
ATCTTCCCTGATTTCATTGA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPYCSYHFKINAVKRLKYTLDED
TFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAGTGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAK
HNLPLVIFSASGGARMQEGILSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGAR
VIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS

Sequences:

>Translated_292_residues
MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPYCSYHFKINAVKRLKYTLDED
TFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAGTGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAK
HNLPLVIFSASGGARMQEGILSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGAR
VIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS
>Mature_292_residues
MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPYCSYHFKINAVKRLKYTLDED
TFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAGTGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAK
HNLPLVIFSASGGARMQEGILSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGAR
VIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:
GO:0000166: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0003989: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0005524: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0005737: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0006633: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0008610: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0009317: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0016874: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
GO:0046872: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=272, Percent_Identity=44.8529411764706, Blast_Score=248, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_ACHLI (A9NFE8)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620454.1
- ProteinModelPortal:   A9NFE8
- SMR:   A9NFE8
- GeneID:   5803109
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0459
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- BioCyc:   ALAI441768:ACL_0459-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32334; Mature: 32334

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPY
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
CSYHFKINAVKRLKYTLDEDTFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAG
EEEEEEEHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHEEC
TGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAKHNLPLVIFSASGGARMQEGI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
LSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGAR
HHHHHHHHHCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS
HHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHLLDERKRRLSQFHEIIKKRPIETRPVDIPDGVFSQCEQCNSAIYNKDLEHNYEVCPY
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
CSYHFKINAVKRLKYTLDEDTFKPLFENITSKNPLGMPEYEEKLDKGMRMAKMNEAFLAG
EEEEEEEHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHEEC
TGKIDGQNLAIGVLDSYFMMGSMGSVVGERITRLIEHAAKHNLPLVIFSASGGARMQEGI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
LSLMQMAKTSGALNLLDEKGLVYISVMTNPTTGGVAASFASLGDINIAEKSSLIGFAGAR
HHHHHHHHHCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIKQTIGQDLPAGFQTDAFQLQKGQVDLVVLRSQLKKTLSTLLKLHAKKVTS
HHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA