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The map label for this gene is pphA [C]

Identifier: 162447264

GI number: 162447264

Start: 418770

End: 419468

Strand: Direct

Name: pphA [C]

Synonym: ACL_0399

Alternate gene names: 162447264

Gene position: 418770-419468 (Clockwise)

Preceding gene: 162447259

Following gene: 162447266

Centisome position: 27.97

GC content: 28.76

Gene sequence:

>699_bases
ATGTCTTTGAAAAAGTATTTTGTCTTTTCTGATATTCATGGTAACTTAAGACCCTTAGTAGAAGCTTTACATAAAGCTGG
TTTTGACATGGAAAATGAAAATCATATACTGTTATCTTTAGGTGATCATTTTGATCGTGGTGTAGAAAATTTAGAAGTAT
TAGGTTATTTAATGTATTTTAATAAACTAAATAGAATCATCATGATTAGAGGTAATCATGATGATTTCTTACTAGATTTT
TTAAAAGGAACTTCAGATGGTATATTTAATATCCAAAAAAATGGTTTTGGTAATACCTTAGCACAATTAGCCAGTAAAGA
TGCAACCACGATACCTAAGATGAGAGATTCTATTAACGAAAGATTTCCAGATTTAATAGCACTTTTAGAATCCATGATAC
ATGAGTTTCAGTTAGGTAAATATATATTTACCCATGCCGGTTATGCCTATTGTAATAAACAAGGATGGTATCTATATAAC
TTTGCTTCTACACCTTACTTTTTAAAGCACTTTGACACAAAAGATAATTATTATGTATTTGGTCATGCCCATGCAAGAGC
CATGAATTATTATGAGTTAGGTGTTGAAAGTAATGATATCTTTGAAATGGATAATTTTATAGGTATTGATGCCAATACAG
TATTAACTAAAGAAGTCCATATCTTAATTTTTGATGAAGAAGGAAATAGACTTTTATAA

Upstream 100 bases:

>100_bases
TTACCTTAATCCTTATGTTATGATATATCTATTATAAACGATAAGTAAGTTTTTATCGTCGAATCTAAACTTTAAAATGT
TAGAATGAATTTATGAGGTG

Downstream 100 bases:

>100_bases
CATATAAATATTTGTATTTAATAAAAATCCGCTTAGGTTGTCCTAGGCGGATTTCTTTATTTATATGTAGAAATACTAAT
TATATTTTTTCGATTAATGA

Product: metallophosphoesterase

Products: A Protein; Orthophosphate. [C]

Alternate protein names: Serine/Threonine Protein Phosphatase Family Protein

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSLKKYFVFSDIHGNLRPLVEALHKAGFDMENENHILLSLGDHFDRGVENLEVLGYLMYFNKLNRIIMIRGNHDDFLLDF
LKGTSDGIFNIQKNGFGNTLAQLASKDATTIPKMRDSINERFPDLIALLESMIHEFQLGKYIFTHAGYAYCNKQGWYLYN
FASTPYFLKHFDTKDNYYVFGHAHARAMNYYELGVESNDIFEMDNFIGIDANTVLTKEVHILIFDEEGNRLL

Sequences:

>Translated_232_residues
MSLKKYFVFSDIHGNLRPLVEALHKAGFDMENENHILLSLGDHFDRGVENLEVLGYLMYFNKLNRIIMIRGNHDDFLLDF
LKGTSDGIFNIQKNGFGNTLAQLASKDATTIPKMRDSINERFPDLIALLESMIHEFQLGKYIFTHAGYAYCNKQGWYLYN
FASTPYFLKHFDTKDNYYVFGHAHARAMNYYELGVESNDIFEMDNFIGIDANTVLTKEVHILIFDEEGNRLL
>Mature_231_residues
SLKKYFVFSDIHGNLRPLVEALHKAGFDMENENHILLSLGDHFDRGVENLEVLGYLMYFNKLNRIIMIRGNHDDFLLDFL
KGTSDGIFNIQKNGFGNTLAQLASKDATTIPKMRDSINERFPDLIALLESMIHEFQLGKYIFTHAGYAYCNKQGWYLYNF
ASTPYFLKHFDTKDNYYVFGHAHARAMNYYELGVESNDIFEMDNFIGIDANTVLTKEVHILIFDEEGNRLL

Specific function: Plays A Key Role In Signaling Protein Misfolding Via The Cpxr/Cpxa Transducing System. It Also Modulates The Phosphorylated Status Of Many Phosphoproteins In E. coli, Some Of Which Acting As Major Chaperones. Has Been Shown, In Vitro, To Act On Ser, Thr A

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.16 [C]

Molecular weight: Translated: 26892; Mature: 26761

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKKYFVFSDIHGNLRPLVEALHKAGFDMENENHILLSLGDHFDRGVENLEVLGYLMYF
CCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
NKLNRIIMIRGNHDDFLLDFLKGTSDGIFNIQKNGFGNTLAQLASKDATTIPKMRDSINE
HHCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHH
RFPDLIALLESMIHEFQLGKYIFTHAGYAYCNKQGWYLYNFASTPYFLKHFDTKDNYYVF
HHHHHHHHHHHHHHHHHHCHHHHHCCCEEEECCCCCEEEEECCCCEEEEEECCCCCEEEE
GHAHARAMNYYELGVESNDIFEMDNFIGIDANTVLTKEVHILIFDEEGNRLL
EEHHHHEEEEEEECCCCCCEEECCCEECCCCCEEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure 
SLKKYFVFSDIHGNLRPLVEALHKAGFDMENENHILLSLGDHFDRGVENLEVLGYLMYF
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
NKLNRIIMIRGNHDDFLLDFLKGTSDGIFNIQKNGFGNTLAQLASKDATTIPKMRDSINE
HHCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHH
RFPDLIALLESMIHEFQLGKYIFTHAGYAYCNKQGWYLYNFASTPYFLKHFDTKDNYYVF
HHHHHHHHHHHHHHHHHHCHHHHHCCCEEEECCCCCEEEEECCCCEEEEEECCCCCEEEE
GHAHARAMNYYELGVESNDIFEMDNFIGIDANTVLTKEVHILIFDEEGNRLL
EEHHHHEEEEEEECCCCCCEEECCCEECCCCCEEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Phosphoprotein; H2O [C]

Specific reaction: A Phosphoprotein + H2O = A Protein + Orthophosphate. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA